Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Christos E Chadjichristos"'
Autor:
Florian Siegerist, Felix Kliewe, Elke Hammer, Paul Schakau, Joanne Ern Chi Soh, Claudia Weber, Maja Lindenmeyer, Simone Reichelt-Wurm, Vedran Drenic, Christos Chatziantoniou, Christos E. Chadjichristos, Yiying Zhang, Stefan Simm, Miriam C. Banas, Matthias Nauck, Uwe Völker, Nicole Endlich
Publikováno v:
iScience, Vol 27, Iss 12, Pp 111329- (2024)
Summary: The tricellular tight junctions are crucial for the regulation of paracellular flux at tricellular junctions, where tricellulin (MARVELD2) and angulins (ILDR1, ILDR2, or LSR) are localized. The role of ILDR2 in podocytes, specialized epithel
Externí odkaz:
https://doaj.org/article/af67c587f3c6454182698827dbc0676d
Autor:
Pierre-Olivier Marchal, Panagiotis Kavvadas, Ahmed Abed, Chantal Kazazian, Florence Authier, Haruhiko Koseki, Shuichi Hiraoka, Jean-Jacques Boffa, Cécile Martinerie, Christos E Chadjichristos
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137876 (2015)
The main hallmark of chronic kidney disease (CKD) is excessive inflammation leading to interstitial tissue fibrosis. It has been recently reported that NOV/CCN3 could be involved in kidney damage but its role in the progression of nephropathies is po
Externí odkaz:
https://doaj.org/article/92fca03d5d38408fb9559029389d84b1
Autor:
Min Li, Silvia Armelloni, Deborah Mattinzoli, Masami Ikehata, Christos Chatziantoniou, Carlo Alfieri, Paolo Molinari, Christos E. Chadjichristos, Silvia Malvica, Giuseppe Castellano
Publikováno v:
Kidney Research and Clinical Practice, Vol 43, Iss 1, Pp 47-62 (2024)
The glomerular filtration barrier (GFB), composed of endothelial cells, glomerular basement membrane, and podocytes, is a unique structure for filtering blood while detaining plasma proteins according to size and charge selectivity. Structurally, the
Externí odkaz:
https://doaj.org/article/f83ad9b91f1a4cbf9462d7b46c564219
Autor:
Anne-Cecile Huby, Panagiotis Kavvadas, Carlo Alfieri, Ahmed Abed, Julie Toubas, Maria-Pia Rastaldi, Jean-Claude Dussaule, Christos Chatziantoniou, Christos E Chadjichristos
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52362 (2012)
BACKGROUND: Several studies have shown that activation of the renin-angiotensin system may lead to hypertension, a major risk factor for the development of chronic kidney disease (CKD). The existing hypertension-induced CDK mouse models are quite fas
Externí odkaz:
https://doaj.org/article/a6607a2d2bec466d852fa3af927ea121
Autor:
Elena Roger, Christos E. Chadjichristos, Panagiotis Kavvadas, Gareth W. Price, Chelsy L. Cliff, Safia Hadjadj, Jessy Renciot, Paul E. Squires, Claire E. Hills
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-20 (2023)
Abstract Background Without a viable cure, chronic kidney disease is a global health concern. Inflammatory damage in and around the renal tubules dictates disease severity and is contributed to by multiple cell types. Activated in response to danger
Externí odkaz:
https://doaj.org/article/e48577cddf834d8685f737c5c38985e6
Autor:
Anxiang Cai, Guanyu Ye, Sandrine Placier, Perrine Frère, Brigitte Surin, Sophie Vandermeersch, Raphael Kormann, Yi-Chun Xu-Dubois, Magali Genest, Morgane Lannoy, Christos E. Chadjichristos, Jean-Claude Dussaule, Peter J. Scambler, Christos Chatziantoniou, Amélie Calmont
Publikováno v:
Kidney International
Kidney International, 2022, 101 (4), pp.720-732. ⟨10.1016/j.kint.2021.12.028⟩
Kidney International, 2022, 101 (4), pp.720-732. ⟨10.1016/j.kint.2021.12.028⟩
International audience; To guide the development of therapeutic interventions for acute kidney injury, elucidating the deleterious pathways of this global health problem is highly warranted. Emerging evidence has indicated a pivotal role of endotheli
Autor:
Virgilia Sahiri, Jonathan Caron, Elena Roger, Christophe Desterke, Khalil Ghachem, Inna Mohamadou, Justine Serre, Niki Prakoura, Soraya Fellahi, Sandrine Placier, Sahil Adriouch, Lu Zhang, Christos E. Chadjichristos, Christos Chatziantoniou, Hans Kristian Lorenzo, Jean-Jacques Boffa
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 3
Pages: 2723
Volume 24
Issue 3
Pages: 2723
Focal segmental glomerulosclerosis (FSGS) is a major cause of end-stage renal disease and remains without specific treatment. To identify new events during FSGS progression, we used an experimental model of FSGS associated with nephroangiosclerosis i
Autor:
Frank Helle, Michael Hultström, Panagiotis Kavvadas, Bjarne Iversen, Christos E. Chadjichristos, Christos Chatziantoniou
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 24; Pages: 16068
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Notch3 plays an important role in the differentiation and development of vascular smooth muscle cells. Mice lacking Notch3 show deficient renal autoregulation. The aim of the study was to investigate the mechanisms involved in the Notch3-mediated con
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2022, 23 (21), pp.13090. ⟨10.3390/ijms232113090⟩
International Journal of Molecular Sciences, 2022, 23 (21), pp.13090. ⟨10.3390/ijms232113090⟩
International audience; Renal disease is a major public health challenge since its prevalence has continuously increased over the last decades. At the end stage, extrarenal replacement therapy and transplantation remain the only treatments currently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20df732d0d38dacdb652c7d972a82a99
https://hal.science/hal-03891976
https://hal.science/hal-03891976
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2022, 23 (6), pp.3124. ⟨10.3390/ijms23063124⟩
International journal of molecular sciences, vol 23, iss 6
International Journal of Molecular Sciences, 2022, 23 (6), pp.3124. ⟨10.3390/ijms23063124⟩
International journal of molecular sciences, vol 23, iss 6
International audience; Galectin-3 (Gal-3) is a 30KDa lectin implicated in multiple pathophysiology pathways including renal damage and fibrosis. Gal-3 binds β-galactoside through its carbohydrate-recognition domain. From intra-cellular to extra-cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b7fa9328bf34a5f46192afb4efa7f6b
https://hal.science/hal-03838218
https://hal.science/hal-03838218