Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Christos E Chadjichristos"'
Autor:
Florian Siegerist, Felix Kliewe, Elke Hammer, Paul Schakau, Joanne Ern Chi Soh, Claudia Weber, Maja Lindenmeyer, Simone Reichelt-Wurm, Vedran Drenic, Christos Chatziantoniou, Christos E. Chadjichristos, Yiying Zhang, Stefan Simm, Miriam C. Banas, Matthias Nauck, Uwe Völker, Nicole Endlich
Publikováno v:
iScience, Vol 27, Iss 12, Pp 111329- (2024)
Summary: The tricellular tight junctions are crucial for the regulation of paracellular flux at tricellular junctions, where tricellulin (MARVELD2) and angulins (ILDR1, ILDR2, or LSR) are localized. The role of ILDR2 in podocytes, specialized epithel
Externí odkaz:
https://doaj.org/article/af67c587f3c6454182698827dbc0676d
Autor:
Min Li, Silvia Armelloni, Deborah Mattinzoli, Masami Ikehata, Christos Chatziantoniou, Carlo Alfieri, Paolo Molinari, Christos E. Chadjichristos, Silvia Malvica, Giuseppe Castellano
Publikováno v:
Kidney Research and Clinical Practice, Vol 43, Iss 1, Pp 47-62 (2024)
The glomerular filtration barrier (GFB), composed of endothelial cells, glomerular basement membrane, and podocytes, is a unique structure for filtering blood while detaining plasma proteins according to size and charge selectivity. Structurally, the
Externí odkaz:
https://doaj.org/article/f83ad9b91f1a4cbf9462d7b46c564219
Autor:
Elena Roger, Christos E. Chadjichristos, Panagiotis Kavvadas, Gareth W. Price, Chelsy L. Cliff, Safia Hadjadj, Jessy Renciot, Paul E. Squires, Claire E. Hills
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-20 (2023)
Abstract Background Without a viable cure, chronic kidney disease is a global health concern. Inflammatory damage in and around the renal tubules dictates disease severity and is contributed to by multiple cell types. Activated in response to danger
Externí odkaz:
https://doaj.org/article/e48577cddf834d8685f737c5c38985e6
Autor:
Gareth W. Price, Christos E. Chadjichristos, Panagiotis Kavvadas, Sydney C. W. Tang, Wai Han Yiu, Colin R. Green, Joe A. Potter, Eleftherios Siamantouras, Paul E. Squires, Claire E. Hills
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-17 (2020)
Abstract Background Tubulointerstitial fibrosis represents the key underlying pathology of Chronic Kidney Disease (CKD), yet treatment options remain limited. In this study, we investigated the role of connexin43 (Cx43) hemichannel-mediated adenosine
Externí odkaz:
https://doaj.org/article/cbf3b5a17eb140fdbcaac434c1479c5c
Autor:
Mathilde Prud’homme, PhD, Maxime Coutrot, MD, MSc, Thibault Michel, MD, MSc, Louis Boutin, MD, MSc, Magali Genest, PhD, Françoise Poirier, PhD, Jean-Marie Launay, PharmD, PhD, Bocar Kane, Satoshi Kinugasa, MD, PhD, Niki Prakoura, PhD, Sophie Vandermeersch, Alain Cohen-Solal, MD, PhD, Claude Delcayre, PhD, Jane-Lise Samuel, MD, PhD, Ravindra Mehta, MD, Etienne Gayat, MD, PhD, Alexandre Mebazaa, MD, PhD, Christos E. Chadjichristos, PhD, Matthieu Legrand, MD, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 6, Pp 717-732 (2019)
Summary: Acute kidney injury is associated with increased risk of heart failure and mortality. This study demonstrates that acute kidney injury induces remote cardiac dysfunction, damage, injury, and fibrosis via a galectin-3 (Gal-3) dependent pathwa
Externí odkaz:
https://doaj.org/article/7f1da282244a4324a0d112605eb113cb
Publikováno v:
Cellular Physiology and Biochemistry, Vol 49, Iss 3, Pp 998-1009 (2018)
Chronic kidney disease is an incurable to date pathology with a continuously growing incidence that contributes to the increase of the number of deaths worldwide. With currently no efficient prognostic or therapeutic options being available, the only
Externí odkaz:
https://doaj.org/article/c5b83a21e4e94e42ab11c10f3be3f79a
Autor:
Anxiang Cai, Guanyu Ye, Sandrine Placier, Perrine Frère, Brigitte Surin, Sophie Vandermeersch, Raphael Kormann, Yi-Chun Xu-Dubois, Magali Genest, Morgane Lannoy, Christos E. Chadjichristos, Jean-Claude Dussaule, Peter J. Scambler, Christos Chatziantoniou, Amélie Calmont
Publikováno v:
Kidney International
Kidney International, 2022, 101 (4), pp.720-732. ⟨10.1016/j.kint.2021.12.028⟩
Kidney International, 2022, 101 (4), pp.720-732. ⟨10.1016/j.kint.2021.12.028⟩
International audience; To guide the development of therapeutic interventions for acute kidney injury, elucidating the deleterious pathways of this global health problem is highly warranted. Emerging evidence has indicated a pivotal role of endotheli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::555c456e75fb4e20178edde7c8426356
https://doi.org/10.1016/j.kint.2021.12.028
https://doi.org/10.1016/j.kint.2021.12.028
Autor:
Virgilia Sahiri, Jonathan Caron, Elena Roger, Christophe Desterke, Khalil Ghachem, Inna Mohamadou, Justine Serre, Niki Prakoura, Soraya Fellahi, Sandrine Placier, Sahil Adriouch, Lu Zhang, Christos E. Chadjichristos, Christos Chatziantoniou, Hans Kristian Lorenzo, Jean-Jacques Boffa
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 3
Pages: 2723
Volume 24
Issue 3
Pages: 2723
Focal segmental glomerulosclerosis (FSGS) is a major cause of end-stage renal disease and remains without specific treatment. To identify new events during FSGS progression, we used an experimental model of FSGS associated with nephroangiosclerosis i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aa3814b131cc94f54b7053ffab32fd2
Autor:
Frank Helle, Michael Hultström, Panagiotis Kavvadas, Bjarne Iversen, Christos E. Chadjichristos, Christos Chatziantoniou
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 24; Pages: 16068
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Notch3 plays an important role in the differentiation and development of vascular smooth muscle cells. Mice lacking Notch3 show deficient renal autoregulation. The aim of the study was to investigate the mechanisms involved in the Notch3-mediated con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92469117b34a032b687ea44c89f36ef0
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2022, 23 (21), pp.13090. ⟨10.3390/ijms232113090⟩
International Journal of Molecular Sciences, 2022, 23 (21), pp.13090. ⟨10.3390/ijms232113090⟩
International audience; Renal disease is a major public health challenge since its prevalence has continuously increased over the last decades. At the end stage, extrarenal replacement therapy and transplantation remain the only treatments currently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20df732d0d38dacdb652c7d972a82a99
https://hal.science/hal-03891976
https://hal.science/hal-03891976
