Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Christos Delidakis"'
Autor:
Zoe Veneti, Virginia Fasoulaki, Nikolaos Kalavros, Ioannis S. Vlachos, Christos Delidakis, Aristides G. Eliopoulos
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Balancing maintenance of self-renewal and differentiation is a key property of adult stem cells. The epigenetic mechanisms controlling this balance remain largely unknown. Herein, we report that the Polycomb Repressive Complex 2 (PRC2) is re
Externí odkaz:
https://doaj.org/article/123a8deb75794cb28d57150b6fc07620
Autor:
Konstantina Kalodimou, Margarita Stapountzi, Nicole Vüllings, Ekaterina Seib, Thomas Klein, Christos Delidakis
Publikováno v:
Cells, Vol 12, Iss 24, p 2833 (2023)
The execution of a Notch signal at the plasma membrane relies on the mechanical force exerted onto Notch by its ligand. It has been appreciated that the DSL ligands need to collaborate with a ubiquitin (Ub) ligase, either Neuralized or Mindbomb1, in
Externí odkaz:
https://doaj.org/article/bd7a264b81ec44f696af942a890b3ad9
Autor:
Vasiliki Theodorou, Aikaterini Stefanaki, Minas Drakos, Dafne Triantafyllou, Christos Delidakis
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-23 (2022)
Abstract Background In both Drosophila and mammals, the achaete-scute (ASC/ASCL) proneural bHLH transcription factors are expressed in the developing central and peripheral nervous systems, where they function during specification and maintenance of
Externí odkaz:
https://doaj.org/article/4e4f456d3e0b46309d19a0659ed6184a
Autor:
Athina Keramidioti, Evgenia Golegou, Eleni Psarra, Nikolaos Paschalidis, Konstantina Kalodimou, Shinya Yamamoto, Christos Delidakis, Katerina M. Vakaloglou, Christos G. Zervas
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Integrins are the major family of transmembrane proteins that mediate cell-matrix adhesion and have a critical role in epithelial morphogenesis. Integrin function largely depends on the indirect connection of the integrin cytoplasmic tail to the acti
Externí odkaz:
https://doaj.org/article/26183c65a358407d8fa6a3f390695847
Autor:
Naama Flint Brodsly, Eliya Bitman-Lotan, Olga Boico, Adi Shafat, Maria Monastirioti, Manfred Gessler, Christos Delidakis, Hector Rincon-Arano, Amir Orian
Publikováno v:
eLife, Vol 8 (2019)
The inability of differentiated cells to maintain their identity is a hallmark of age-related diseases. We found that the transcription factor Hey supervises the identity of differentiated enterocytes (ECs) in the adult Drosophila midgut. Lineage tra
Externí odkaz:
https://doaj.org/article/01c984f6dcdf4551a99d8a95c4cf63fc
Autor:
Nicole Berndt, Ekaterina Seib, Soya Kim, Tobias Troost, Marvin Lyga, Jessica Langenbach, Sebastian Haensch, Konstantina Kalodimou, Christos Delidakis, Thomas Klein
Publikováno v:
eLife, Vol 6 (2017)
Ubiquitylation (ubi) by the E3-ligases Mindbomb1 (Mib1) and Neuralized (Neur) is required for activation of the DSL ligands Delta (Dl) and Serrate (Ser) to activate Notch signalling. These ligases transfer ubiquitin to lysines of the ligands' intrace
Externí odkaz:
https://doaj.org/article/6c3883d977c54f37b368fed7de5158d6
Autor:
Chrysanthi Voutyraki, Alexandros Choromidis, Vasiliki Theodorou, Christina Efraimoglou, Gerasimos Anagnostopoulos, Srivathsa S. Magadi, Sofia Grammenoudi, Evanthia Zacharioudaki, Christos Delidakis
Publikováno v:
The International Journal of Developmental Biology. 66:211-222
Background: Neural stem cells (NSC) in divide asymmetrically to generate one cell that retains stem cell identity and another that is routed to differentiation. Prolonged mitotic activity of the NSCs gives rise to the plethora of neurons and glial ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b725ee91dfc6d1c5db5f71631d10a2fd
https://doi.org/10.1387/ijdb.210187cd
https://doi.org/10.1387/ijdb.210187cd
Publikováno v:
The International journal of developmental biology. 66(1-2-3)
Hey is a conserved transcription factor of the bHLH-Orange family that participates in the response to Notch signaling in certain tissues. Whereas three Hey paralogues exist in mammalian genomes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a3b7f0fedb76fdb091d3bb1714782241
https://pubmed.ncbi.nlm.nih.gov/34881798
https://pubmed.ncbi.nlm.nih.gov/34881798
Autor:
Chrysanthi, Voutyraki, Alexandros, Choromidis, Vasiliki, Theodorou, Christina, Efraimoglou, Gerasimos, Anagnostopoulos, Srivathsa S, Magadi, Sofia, Grammenoudi, Evanthia, Zacharioudaki, Christos, Delidakis
Publikováno v:
The International journal of developmental biology. 66(1-2-3)
Neural stem cells (NSC) in divide asymmetrically to generate one cell that retains stem cell identity and another that is routed to differentiation. Prolonged mitotic activity of the NSCs gives rise to the plethora of neurons and glial cells that wir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::44890d9eeabcb8c2e9f2059ea3f7cc21
https://pubmed.ncbi.nlm.nih.gov/34881794
https://pubmed.ncbi.nlm.nih.gov/34881794
Autor:
Minas Drakos, Dafne Triantafyllou, Vasiliki Theodorou, Aikaterini Stefanaki, Christos Delidakis
BackgroundASC/ASCL proneural transcription factors are oncogenic and exhibit impressive reprogramming and pioneer activities. In both Drosophila and mammals, these factors are central in the early specification of the neural fate, where they act in o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c785843fd360caf502b14eb86f94957
https://doi.org/10.1101/2021.11.02.466869
https://doi.org/10.1101/2021.11.02.466869
