Zobrazeno 1 - 10
of 165
pro vyhledávání: '"Christos Chatziantoniou"'
Autor:
Cláudio Rodrigues Rezende Costa, Rym Chalgoumi, Amina Baker, Clément Guillou, Paulo Marcio Yamaguti, Victor Simancas Escorcia, Lilia Abbad, Bruna Rabelo Amorin, Caroline Lourenço de Lima, Vidjea Cannaya, Mourad Benassarou, Ariane Berdal, Christos Chatziantoniou, Olivier Cases, Pascal Cosette, Renata Kozyraki, Ana Carolina Acevedo
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-24 (2024)
Abstract Raine syndrome (RNS) is a rare autosomal recessive osteosclerotic dysplasia. RNS is caused by loss-of-function disease-causative variants of the FAM20C gene that encodes a kinase that phosphorylates most of the secreted proteins found in the
Externí odkaz:
https://doaj.org/article/9aa2eb1bfd614d948b1a01bc52bdd27a
Autor:
Min Li, Silvia Armelloni, Deborah Mattinzoli, Masami Ikehata, Christos Chatziantoniou, Carlo Alfieri, Paolo Molinari, Christos E. Chadjichristos, Silvia Malvica, Giuseppe Castellano
Publikováno v:
Kidney Research and Clinical Practice, Vol 43, Iss 1, Pp 47-62 (2024)
The glomerular filtration barrier (GFB), composed of endothelial cells, glomerular basement membrane, and podocytes, is a unique structure for filtering blood while detaining plasma proteins according to size and charge selectivity. Structurally, the
Externí odkaz:
https://doaj.org/article/f83ad9b91f1a4cbf9462d7b46c564219
Autor:
Virgilia Sahiri, Jonathan Caron, Elena Roger, Christophe Desterke, Khalil Ghachem, Inna Mohamadou, Justine Serre, Niki Prakoura, Soraya Fellahi, Sandrine Placier, Sahil Adriouch, Lu Zhang, Christos E. Chadjichristos, Christos Chatziantoniou, Hans Kristian Lorenzo, Jean-Jacques Boffa
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2723 (2023)
Focal segmental glomerulosclerosis (FSGS) is a major cause of end-stage renal disease and remains without specific treatment. To identify new events during FSGS progression, we used an experimental model of FSGS associated with nephroangiosclerosis i
Externí odkaz:
https://doaj.org/article/51c8b741c93049e1bce700df639423a8
Autor:
Frank Helle, Michael Hultström, Panagiotis Kavvadas, Bjarne Iversen, Christos E. Chadjichristos, Christos Chatziantoniou
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 16068 (2022)
Notch3 plays an important role in the differentiation and development of vascular smooth muscle cells. Mice lacking Notch3 show deficient renal autoregulation. The aim of the study was to investigate the mechanisms involved in the Notch3-mediated con
Externí odkaz:
https://doaj.org/article/5a6fff5020dd4b48b62bef5a39c2fcfe
Autor:
Victor Simancas Escorcia, Clément Guillou, Lilia Abbad, Louise Derrien, Claudio Rodrigues Rezende Costa, Vidjea Cannaya, Mourad Benassarou, Christos Chatziantoniou, Ariane Berdal, Ana Carolina Acevedo, Olivier Cases, Pascal Cosette, Renata Kozyraki
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
The enamel renal syndrome (ERS) is a rare disorder featured by amelogenesis imperfecta, gingival fibromatosis and nephrocalcinosis. ERS is caused by bi-allelic mutations in the secretory pathway pseudokinase FAM20A. How mutations in FAM20A may modify
Externí odkaz:
https://doaj.org/article/ba501b066ef74343a191805841009ed8
Autor:
Lilia Abbad, Niki Prakoura, Arthur Michon, Rym Chalghoumi, Simone Reichelt-Wurm, Miriam C. Banas, Christos Chatziantoniou
Publikováno v:
Cells, Vol 11, Iss 14, p 2212 (2022)
Diabetic nephropathy (DN) remains the most common reason for end-stage renal disease and a leading cause of kidney replacement therapy. Multifactorial pathophysiological mechanisms underlie the development of DN. Among the signalling pathways involve
Externí odkaz:
https://doaj.org/article/1e3d47c8f3e2424799f5e3b191ddc71d
Autor:
Victor Simancas Escorcia, Abdoulaziz Diarra, Adrien Naveau, Arnaud Dessombz, Rufino Felizardo, Vidjeacoumary Cannaya, Christos Chatziantoniou, Mickaël Quentric, Miikka Vikkula, Olivier Cases, Ariane Berdal, Muriel De La Dure-Molla, Renata Kozyraki
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Enamel renal syndrome (ERS) is a rare recessive disorder caused by loss-of-function mutations in FAM20A (family with sequence similarity 20 member A, OMIM #611062). Enamel renal syndrome is characterized by amelogenesis imperfecta, delayed or failed
Externí odkaz:
https://doaj.org/article/406c84b6f3bc4895964e613dd15074e0
Autor:
Sonja Djudjaj, Panagiotis Kavvadas, Niki Prakoura, Roman D. Bülow, Tiffany Migeon, Sandrine Placier, Christos E. Chadjichristos, Peter Boor, Christos Chatziantoniou
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 2, p 884 (2022)
Background: Polycystic kidney disease (PKD) is a genetic disorder affecting millions of people worldwide that is characterized by fluid-filled cysts and leads to end-stage renal disease (ESRD). The hallmarks of PKD are proliferation and dedifferentia
Externí odkaz:
https://doaj.org/article/6142c25eb91847a2b416ec23fc5dc158
Autor:
Solange Moll, Yukari Yasui, Ahmed Abed, Takeshi Murata, Hideaki Shimada, Akira Maeda, Naoshi Fukushima, Masakazu Kanamori, Sabine Uhles, Laura Badi, Thomas Cagarelli, Ivan Formentini, Faye Drawnel, Guy Georges, Tobias Bergauer, Rodolfo Gasser, R. Daniel Bonfil, Rafael Fridman, Hans Richter, Juergen Funk, Marcus J. Moeller, Christos Chatziantoniou, Marco Prunotto
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-20 (2018)
Abstract Background Discoidin domain receptor 1 (DDR1) is a collagen-activated receptor tyrosine kinase extensively implicated in diseases such as cancer, atherosclerosis and fibrosis. Multiple preclinical studies, performed using either a gene delet
Externí odkaz:
https://doaj.org/article/e3e373ca595c4969a8633dea690e672b
Autor:
Niki Prakoura, Christos Chatziantoniou
Publikováno v:
Frontiers in Medicine, Vol 4 (2017)
Chronic kidney disease (CKD) can be a life-threatening condition, which eventually requires renal replacement therapy through dialysis or transplantation. A lot of effort and resources have been invested the last years in the identification of novel
Externí odkaz:
https://doaj.org/article/8bfc10933089452899b20d7e0805e739