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Autor:
Orit Shevah, Christos Bechlivanides, Sanda Nousia-Arvanitakis, Assimina Galli-Tsinopoulou, Ioannis Tsinopoulos, Zvi Laron
Publikováno v:
HORMONES. 2:120-124
Laron-type dwarfism is an autosomal recessive disorder caused by deletions or mutations of the growth hormone receptor gene. It is characterized by high circulating levels of growth hormone (GH) and low levels of insulin-like growth factor I (IGF-I).