Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Christopher Zelinka"'
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e10774 (2010)
We have recently described a novel type of glial cell that is scattered across the inner layers of the avian retina [1]. These cells are stimulated by insulin-like growth factor 1 (IGF1) to proliferate, migrate distally into the retina, and up-regula
Externí odkaz:
https://doaj.org/article/1e77352a9b714c189405057a016603ce
Autor:
Paul G. Curran, Andy J. Fischer, Joshua T. Bartoe, Kenneth E. Pierce, Christopher Zelinka, Simon M. Petersen-Jones
Publikováno v:
Retinal Degenerative Diseases ISBN: 9783030273774
This study was designed to assess risk for retinal toxicity associated with administration of high-dose sildenafil citrate to dogs heterozygous for a functionally null mutation in Pde6a over a 4-month period. Three Pde6a +/− dogs were administered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb05ccbc8a273d6428278f2e887e8a6c
https://doi.org/10.1007/978-3-030-27378-1_61
https://doi.org/10.1007/978-3-030-27378-1_61
Autor:
Christopher Zelinka, Levi Todd
Publikováno v:
The Journal of Neuroscience. 37:5215-5217
Retinitis pigmentosa (RP) is a family of heritable retinopathies characterized by a progressive loss of rod photoreceptors that eventually leads to blindness. Hundreds of individual mutations found in >60 genes are known to result in RP, with varying
Publikováno v:
Experimental Neurology. 273:114-125
Reactive microglia and macrophages are prevalent in damaged retinas. Glucocorticoid signaling is known to suppress inflammation and the reactivity of microglia and macrophages. In the vertebrate retina, the glucocorticoid receptor (GCR) is known to b
Autor:
Kevin M. Gribbins, Natalie Squires, Levi Todd, Andy J. Fischer, Lilianna Suarez, Christopher Zelinka
Publikováno v:
Journal of Comparative Neurology. 524:74-89
Retinal progenitors in the circumferential marginal zone (CMZ) and Muller glia-derived progenitors have been well described for the eyes of fish, amphibians, and birds. However, there is no information regarding a CMZ and the nature of retinal glia i
Publikováno v:
Glia. 63:313-327
Reactive microglia and macrophages are prevalent in damaged retinas. Accordingly, we investigate how the activation or ablation of microglia/macrophages influences the survival of neurons in the chick retina in vivo. We applied intraocular injections
Publikováno v:
Development. 141:3340-3351
Identification of the signaling pathways that influence the reprogramming of Müller glia into neurogenic retinal progenitors is key to harnessing the potential of these cells to regenerate the retina. Glucocorticoid receptor (GCR) signaling is commo
Publikováno v:
Glia. 62:1608-1628
In retinas where M€ glia have been stimulated to become progenitor cells, reactive microglia are always present. Thus, we investigated how the activation or ablation of microglia/macrophage influences the formation of M€ glia-derived progenitor c
Publikováno v:
Experimental Eye Research. 99:1-16
Different growth factors have been shown to influence the development of form-deprivation myopia and lens-induced ametropias. However, growth factors have relatively little effect on the growth of eyes with unrestricted vision. We investigate whether
Autor:
Rachel Bongini, Eric R. Ritchey, Kimberly A. Code, Christopher Zelinka, Simon M. Petersen-Jones, Andy J. Fischer
Publikováno v:
Neuroscience. 169:1376-1391
Guanine nucleotide-binding protein β3 (GNB3) is an isoform of the β subunit of the heterotrimeric G protein second messenger complex that is commonly associated with transmembrane receptors. The presence of GNB3 in photoreceptors, and possibly bipo