Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Christopher Yau"'
Autor:
Hanwen Xing, Christopher Yau
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-16 (2024)
Abstract The identification of tumor-specific molecular dependencies is essential for the development of effective cancer therapies. Genetic and chemical perturbations are powerful tools for discovering these dependencies. Even though chemical pertur
Externí odkaz:
https://doaj.org/article/cadc1165eea14534b144abf4ea37bc86
Autor:
Steven Wambua, Megha Singh, Kelvin Okoth, Kym I. E. Snell, Richard D. Riley, Christopher Yau, Shakila Thangaratinam, Krishnarajah Nirantharakumar, Francesca L. Crowe, on behalf of the MuM-PreDiCT Group
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-23 (2024)
Abstract Background Despite many systematic reviews and meta-analyses examining the associations of pregnancy complications with risk of type 2 diabetes mellitus (T2DM) and hypertension, previous umbrella reviews have only examined a single pregnancy
Externí odkaz:
https://doaj.org/article/7f1385cccf1047fdb5b440ee6742d94a
Autor:
Alexander P. L. Martindale, Carrie D. Llewellyn, Richard O. de Visser, Benjamin Ng, Victoria Ngai, Aditya U. Kale, Lavinia Ferrante di Ruffano, Robert M. Golub, Gary S. Collins, David Moher, Melissa D. McCradden, Lauren Oakden-Rayner, Samantha Cruz Rivera, Melanie Calvert, Christopher J. Kelly, Cecilia S. Lee, Christopher Yau, An-Wen Chan, Pearse A. Keane, Andrew L. Beam, Alastair K. Denniston, Xiaoxuan Liu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract The Consolidated Standards of Reporting Trials extension for Artificial Intelligence interventions (CONSORT-AI) was published in September 2020. Since its publication, several randomised controlled trials (RCTs) of AI interventions have been
Externí odkaz:
https://doaj.org/article/a2d27b1908784851a58e618b7b71f7b0
Autor:
Joel Nulsen, Nosheen Hussain, Aws Al-Deka, Jason Yap, Khalil Uddin, Christopher Yau, Ahmed Ashour Ahmed
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-17 (2023)
Abstract Background Genomic insights in settings where tumour sample sizes are limited to just hundreds or even tens of cells hold great clinical potential, but also present significant technical challenges. We previously developed the DigiPico seque
Externí odkaz:
https://doaj.org/article/a1b03ef623f74a5faaf236a7f568ea75
Autor:
Alexander P. L. Martindale, Carrie D. Llewellyn, Richard O. de Visser, Benjamin Ng, Victoria Ngai, Aditya U. Kale, Lavinia Ferrante di Ruffano, Robert M. Golub, Gary S. Collins, David Moher, Melissa D. McCradden, Lauren Oakden-Rayner, Samantha Cruz Rivera, Melanie Calvert, Christopher J. Kelly, Cecilia S. Lee, Christopher Yau, An-Wen Chan, Pearse A. Keane, Andrew L. Beam, Alastair K. Denniston, Xiaoxuan Liu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/8c62a46cdbbb49cf9eb4752d6f008c03
Autor:
Siang Ing Lee, Stephanie Hanley, Zoe Vowles, Rachel Plachcinski, Ngawai Moss, Megha Singh, Chris Gale, Adeniyi Francis Fagbamigbe, Amaya Azcoaga-Lorenzo, Anuradhaa Subramanian, Beck Taylor, Catherine Nelson-Piercy, Christine Damase-Michel, Christopher Yau, Colin McCowan, Dermot O’Reilly, Gillian Santorelli, Helen Dolk, Holly Hope, Katherine Phillips, Kathryn M. Abel, Kelly-Ann Eastwood, Lisa Kent, Louise Locock, Maria Loane, Mohamed Mhereeg, Peter Brocklehurst, Sharon McCann, Sinead Brophy, Steven Wambua, Sudasing Pathirannehelage Buddhika Hemali Sudasinghe, Shakila Thangaratinam, Krishnarajah Nirantharakumar, Mairead Black, on behalf of the MuM-PreDiCT Group
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Heterogeneity in reported outcomes can limit the synthesis of research evidence. A core outcome set informs what outcomes are important and should be measured as a minimum in all future studies. We report the development of a core
Externí odkaz:
https://doaj.org/article/bbbd89b7413e4407b8c558ead301eb78
Autor:
Christopher Yau Man Luk, Seul A. Lee, Nicholas Naidovski, Fang Liu, Alfred Chin Yen Tay, Liang Wang, Stephen Riordan, Li Zhang
Publikováno v:
Frontiers in Microbiology, Vol 14 (2024)
Campylobacter concisus is an oral bacterium. Recent studies suggest that C. concisus may be involved in human gastric diseases. The mechanisms, however, by which C. concisus causes human gastric diseases have not been investigated. Here we examined t
Externí odkaz:
https://doaj.org/article/8167e65321a14c13901a810e3a5e7eed
Autor:
Sida Chen, Tom Marshall, Christopher Jackson, Jennifer Cooper, Francesca Crowe, Krish Nirantharakumar, Catherine L Saunders, Paul Kirk, Sylvia Richardson, Duncan Edwards, Simon Griffin, Christopher Yau, Jessica K Barrett
Publikováno v:
PLoS Medicine, Vol 20, Iss 11, p e1004310 (2023)
BackgroundMultimorbidity, characterised by the coexistence of multiple chronic conditions in an individual, is a rising public health concern. While much of the existing research has focused on cross-sectional patterns of multimorbidity, there remain
Externí odkaz:
https://doaj.org/article/aac8736d9ebb43ccbfbd0ea84cb4a510
Autor:
Christopher Yau, Catherine Nelson-Piercy, Krishnarajah Nirantharakumar, Anuradhaa Subramanian, Peter Brocklehurst, Sinead Brophy, Helen Dolk, Muhammad Usman, Jingya Wang, Colin McCowan, Holly Hope, Jonathan Kennedy, Siang Ing Lee, Amaya Azcoaga-Lorenzo, Gillian Santorelli, Mairead Black, Christine Damase-Michel, Ngawai Moss, Katherine Phillips, Kelly-Ann Eastwood, Kathryn Mary Abel, Lisa Kent, Adeniyi Fagbamigbe, Dermot OReilly, Steven Wambua, Megha Singh, Mohamed Mhereeg, Neil Cockburn, Sudasing Pathirannehelage Buddhika Hemali Sudasinghe
Publikováno v:
BMJ Open, Vol 13, Iss 10 (2023)
Introduction Considering the high prevalence of polypharmacy in pregnant women and the knowledge gap in the risk–benefit safety profile of their often-complex treatment plan, more research is needed to optimise prescribing. In this study, we aim to
Externí odkaz:
https://doaj.org/article/f51203954be24382ac100c80d2415f9e
Autor:
Anuradhaa Subramanian, Amaya Azcoaga-Lorenzo, Astha Anand, Katherine Phillips, Siang Ing Lee, Neil Cockburn, Adeniyi Francis Fagbamigbe, Christine Damase-Michel, Christopher Yau, Colin McCowan, Dermot O’Reilly, Gillian Santorelli, Holly Hope, Jonathan I. Kennedy, Kathryn M. Abel, Kelly-Ann Eastwood, Louise Locock, Mairead Black, Maria Loane, Ngawai Moss, Rachel Plachcinski, Shakila Thangaratinam, Sinead Brophy, Utkarsh Agrawal, Zoe Vowles, Peter Brocklehurst, Helen Dolk, Catherine Nelson-Piercy, Krishnarajah Nirantharakumar, on behalf of the MuM-PreDiCT Group
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Background The number of medications prescribed during pregnancy has increased over the past few decades. Few studies have described the prevalence of multiple medication use among pregnant women. This study aims to describe the overall prev
Externí odkaz:
https://doaj.org/article/3de01466eba041e88d0ea3b14fb0f209