Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Christopher Weidenmaier"'
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Extracellular vesicles (EVs) influence host-pathogen interactions, but EV biogenesis in gram-positive bacteria remains elusive. Here authors characterize EVs from Staphylococcus aureus and show that phenol-soluble modulins and autolysins promote EV b
Externí odkaz:
https://doaj.org/article/f19b7be7eb15436384641271771b100d
Autor:
Rob van Dalen, Jacinto S. De La Cruz Diaz, Matevž Rumpret, Felix F. Fuchsberger, Nienke H. van Teijlingen, Jonas Hanske, Christoph Rademacher, Teunis B. H. Geijtenbeek, Jos A. G. van Strijp, Christopher Weidenmaier, Andreas Peschel, Daniel H. Kaplan, Nina M. van Sorge
Publikováno v:
mBio, Vol 10, Iss 3 (2019)
ABSTRACT Staphylococcus aureus is a major cause of skin and soft tissue infections and aggravator of the inflammatory skin disease atopic dermatitis (AD [eczema]). Epicutaneous exposure to S. aureus induces Th17 responses through skin Langerhans cell
Externí odkaz:
https://doaj.org/article/5381197dcad241c8928ae7c4eb2becaf
Autor:
Hartmut Stoll, Michael Ost, Anurag Singh, Roman Mehling, Davide Neri, Iris Schäfer, Ana Velic, Boris Macek, Dorothee Kretschmer, Christopher Weidenmaier, Andreas Hector, Rupert Handgretinger, Friedrich Götz, Andreas Peschel, Dominik Hartl, Nikolaus Rieber
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
Staphylococcus aureus is one of the major human bacterial pathogens causing a broad spectrum of serious infections. Myeloid-derived suppressor cells (MDSC) represent an innate immune cell subset capable of regulating host-pathogen interactions, yet t
Externí odkaz:
https://doaj.org/article/2463ab7f472b421ca7d69dfa8c87d48a
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150907 (2016)
Treatment of Staphylococcus aureus in stationary growth phase with high doses of the antibiotic daptomycin (DAP) eradicates the vast majority of the culture and leaves persister cells behind. Despite resting in a drug-tolerant and dormant state, pers
Externí odkaz:
https://doaj.org/article/edda6bf7614f43e9b426493a99431e31
Autor:
Volker Winstel, Petra Kühner, Ferdinand Salomon, Jesper Larsen, Robert Skov, Wolfgang Hoffmann, Andreas Peschel, Christopher Weidenmaier
Publikováno v:
mBio, Vol 6, Iss 4 (2015)
ABSTRACT Nasal colonization by the human pathogen Staphylococcus aureus is a major risk factor for hospital- and community-acquired infections. A key factor required for nasal colonization is a cell surface-exposed zwitterionic glycopolymer, termed w
Externí odkaz:
https://doaj.org/article/5743d590b37e449ebd3f858f2fe094c9
Autor:
Stefanie Baur, Maren Rautenberg, Michaela Faulstich, Timo Grau, Yannik Severin, Clemens Unger, Wolfgang H Hoffmann, Thomas Rudel, Ingo B Autenrieth, Christopher Weidenmaier
Publikováno v:
PLoS Pathogens, Vol 10, Iss 5, p e1004089 (2014)
Nasal colonization is a major risk factor for S. aureus infections. The mechanisms responsible for colonization are still not well understood and involve several factors on the host and the bacterial side. One key factor is the cell wall teichoic aci
Externí odkaz:
https://doaj.org/article/504affc46ac54dada6842e3ab00761dc
Nutrient limitation governs Staphylococcus aureus metabolism and niche adaptation in the human nose.
Autor:
Bernhard Krismer, Manuel Liebeke, Daniela Janek, Mulugeta Nega, Maren Rautenberg, Gabriele Hornig, Clemens Unger, Christopher Weidenmaier, Michael Lalk, Andreas Peschel
Publikováno v:
PLoS Pathogens, Vol 10, Iss 1, p e1003862 (2014)
Colonization of the human nose by Staphylococcus aureus in one-third of the population represents a major risk factor for invasive infections. The basis for adaptation of S. aureus to this specific habitat and reasons for the human predisposition to
Externí odkaz:
https://doaj.org/article/691fdf177f6f4b32b6980daf62c8ba87
Autor:
Nagendra N Mishra, Arnold S Bayer, Christopher Weidenmaier, Timo Grau, Stefanie Wanner, Stefania Stefani, Viviana Cafiso, Taschia Bertuccio, Michael R Yeaman, Cynthia C Nast, Soo-Jin Yang
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107426 (2014)
Development of in vivo daptomycin resistance (DAP-R) among Staphylococcus aureus clinical isolates, in association with clinical treatment failures, has become a major therapeutic problem. This issue is especially relevant to methicillin-resistant S.
Externí odkaz:
https://doaj.org/article/ce533c70c5fe476cb1e4d180dcca77f3
Autor:
Ute Bertsche, Soo-Jin Yang, Daniel Kuehner, Stefanie Wanner, Nagendra N Mishra, Tobias Roth, Mulugeta Nega, Alexander Schneider, Christoph Mayer, Timo Grau, Arnold S Bayer, Christopher Weidenmaier
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67398 (2013)
Multiple mechanisms have been correlated with daptomycin-resistance (DAP-R) in Staphylococcus aureus. However, one common phenotype observed in many DAP-R S. Aureus strains is a thickened cell wall (CW). The first evidence for an impact of CW-linked
Externí odkaz:
https://doaj.org/article/7e62a14fa94a4dc7a5607c978694f104
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13227 (2010)
Zwitterionic polysaccharide (ZPS) components of the bacterial cell envelope have been shown to exert a major histocompatibility complex (MHC) II-dependent activation of CD4+ T cells, which in turn can modulate the outcome and progression of infection
Externí odkaz:
https://doaj.org/article/715f13f42def481d8af6f4fa74229ef9