Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Christopher W. Tsang"'
Autor:
Christopher W. Tsang, William S. Trimble, Hong Xie, Mathew P. Estey, Dana Patterson, Jessica E. DiCiccio
Publikováno v:
Biological chemistry. 392(8-9)
Septins are GTPases that form heteromeric complexes and are linked to neurological disorders. Although several septin subcomplexes have been reported in various mammalian tissues, the cellular and subcellular distribution of these complexes is largel
Autor:
Natasha Zinck, Karen Colwill, William S. Trimble, Lindsay Richier, Tony Pawson, Pavel Metalnikov, James P. Fawcett, Michael O'Brien, Stefan R. Krueger, Leanne Clattenburg, Kelly Williton, Christopher W. Tsang, Annette Kolar
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 30(13)
The formation and function of the neuronal synapse is dependent on the asymmetric distribution of proteins both presynaptically and postsynaptically. Recently, proteins important in establishing cellular polarity have been implicated in the synapse.
Autor:
Jing Xue, John R. Harrison, Lu-Yang Wang, Christopher W. Tsang, Hong Xie, Michael J. Fedchyshyn, William S. Trimble, Phillip J. Robinson
The septin family of GTPases, first identified for their roles in cell division, are also expressed in postmitotic tissues. SEPT3 (G-septin) and SEPT5 (CDCrel-1) are highly expressed in neurons, enriched in presynaptic terminals, and associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad8ca04d44e0813c7768da2a5dbd2b9d
https://europepmc.org/articles/PMC2593370/
https://europepmc.org/articles/PMC2593370/
Publikováno v:
Traffic (Copenhagen, Denmark). 6(8)
The physical division of one cell into two requires the highly orchestrated separation of genetic and cytoplasmic contents during M phase of the cell cycle. Mitosis, the physical segregation of the genetic material of a cell into two daughter cells,
Autor:
Wei Ping Gai, William S. Trimble, Christopher W. Tsang, Chandra S. Malladi, Phillip J. Robinson, Jing Xue, John A.P. Rostas
Publikováno v:
Journal of neurochemistry. 91(3)
The septins are GTPase enzymes with multiple roles in cytokinesis, cell polarity or exocytosis. The proteins from the mammalian septin genes are called Sept1-10. Most are expressed in multiple tissues, but the mRNA for Sept5 (CDCrel-1) and Sept3 (G-s
Publikováno v:
Molecular biology of the cell. 13(10)
Cytokinesis in animal cells involves the contraction of an actomyosin ring formed at the cleavage furrow. Nuclear division, or karyokinesis, must be precisely timed to occur before cytokinesis in order to prevent genetic anomalies that would result i
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 20(23)
α-Latrotoxin (α-LTX) is a neurotoxin that accelerates spontaneous exocytosis independently of extracellular Ca2+. Although α-LTX increases spontaneous transmitter release at synapses, the mechanism is unknown. We tested the hypothesis that α-LTX
Autor:
Hong Xie, Lu-Yang Wang, Jamila Aitoubah, Cameron A. Ackerley, Giovanbattista Grande, William S. Trimble, Christopher W. Tsang, Yi Mei Yang, Michael J. Fedchyshyn
Publikováno v:
Neuron. (1):100-115
SummaryNeurotransmitter release depends critically on close spatial coupling of Ca2+ entry to synaptic vesicles at the nerve terminal; however, the molecular substrates determining their physical proximity are unknown. Using the calyx of Held synapse