Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Christopher W. PERRETT"'
Publikováno v:
Journal of Oncology
Journal of Oncology, Vol 2012 (2012)
Journal of Oncology, Vol 2012 (2012)
Our understanding of the pathogenesis of Paget's disease of the vulva and the breast remains limited. Current evidence supports the fact that angiogenesis plays an important role in the pathogenesis of several diseases. Therefore, we sought to define
Publikováno v:
Cellular Signalling. 9:71-78
In the endocrine pancreas, alpha 2-adrenoceptor stimulation reduces glucose-induced insulin secretion from islet B-cells. There is, however, controversy with regard to the effects of alpha 2-agonists on islet A-cell function. In this paper, we have u
Autor:
C. Musgrove, Richard C. Strange, William E. Farrell, Charles W.E. Redman, V. Suarez, Anthony A. Fryer, Brannigan K, Peter W. Jones, P. Hand, P. Sarhanis, Richard N. Clayton, Christopher W. Perrett
Publikováno v:
British Journal of Cancer
The importance of polymorphism in the glutathione S-transferase GSTM1, GSTT1 and, cytochrome P450, CYP2D6 loci in the pathogenesis of epithelial ovarian cancer has been assessed in two studies; firstly, a case-control study designed to determine the
Publikováno v:
Molecular Brain Research. 12:163-171
Total cellular polyadenylated RNA (poly(A)+ RNA, mRNA) was prepared aftter guanidinium thiocyanate extraction of frozen brain tissue from age-matched controls and patients suffering from schizophrenia and unipolar depression. These mRNA populations w
Publikováno v:
Electrophoresis. 12:584-588
Poly (A+ mRNA species, isolated from 100-day-old rat brain, were analysed by in vitro translation and two-dimensional gel electrophoresis. The synthesis of selected protein species was compared to actin on the basis of [35S]methionine incorporation.
Autor:
Lois J, Eva, Kerstin J, Rolfe, Allan B, MacLean, Wendy M N, Reid, Anne Christine Wong Te, Fong, Julie, Crow, Christopher W, Perrett
Publikováno v:
The Journal of reproductive medicine. 52(5)
To perform a pilot study to investigate the relationship between localized, provoked vulvodynia of the vestibule and inflammatory cytokine expression.Women with a diagnosis of localized, provoked vulvodynia had tissue samples taken for vulvar express
Autor:
Jose, Mullerat, Christopher W, Perrett, Florence, Deroide, Mark C, Winslet, Margarita, Bofill, Leonard W, Poulters
Publikováno v:
Anticancer research. 25(2A)
While macrophages (CD68+) have been associated with angiogenesis in some inflammatory and neoplastic processes by increasing the release of vascular endothelial growth factor (VEGF), their role in anal intraepithelial neoplasia (AIN) and anal squamou
Autor:
Massimilio Scanarini, Nicola Buckley, Christopher W. Perrett, Janice Gilford, Richard N. Clayton, Richard C. Strange, Peter W. Jones, Marco Boscaro, Julie Alldersea, Andrew S. Bates, Anthony A. Fryer, Matteo Pistorello
Publikováno v:
Carcinogenesis. 16(7)
We describe studies to determine if susceptibility to pituitary tumours is associated with the putatively high risk GSTM1 null and CYP2D6 EM genotypes. Frequency distributions of these genotypes were similar in cases and controls though the frequency
Autor:
N. Buckley, Richard N. Clayton, Christopher W. Perrett, M. D. Boggild, John C. Broome, E. J. Bicknell, A. S. Bates
Publikováno v:
Clinical endocrinology. 42(6)
A 30-year-old presented in 1984 with a clinically nonfunctional tumour which subsequently developed into a metastatic corticotrophinoma from which he died despite surgery in 1984, 1986 and 1991 and external radiotherapy in 1986. Molecular genetic ana
Are activating mutations of the adrenocorticotropin receptor involved in adrenal cortical neoplasia?
Autor:
M. Pistorello, K. Light, Paul J. Jenkins, A. Weber, Adrian J. L. Clark, Sylvia L. Asa, Christopher W. Perrett, Richard N. Clayton, Ashley B. Grossman
Publikováno v:
Life sciences. 56(18)
The objective of this study was to investigate the presence of activating mutations of the ACTH receptor gene in benign and malignant adrenocortical tumours. Genomic DNA was extracted from a variety of adrenocortical neoplasms from 16 patients and th