Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Christopher W. Brownlee"'
Publikováno v:
Exp Cell Res
Size is a fundamental feature of biology that affects physiology at all levels, from the organism to organs and tissues to cells and subcellular structures. How size is determined at these different levels, and how biological structures scale to fit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ba2160f013875585643f6368237df66
https://europepmc.org/articles/PMC7246146/
https://europepmc.org/articles/PMC7246146/
Autor:
Christopher W. Brownlee, Rebecca Heald
Publikováno v:
Developmental Cell. 45:421-423
As cell size decreases during the reductive divisions of early development, intracellular structures must shrink to fit. In this issue of Developmental Cell, Lacroix et al. (2018) identify a conserved mechanism of spindle scaling in nematode and sea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75285bf542a7491ae6c7e09451d70799
https://doi.org/10.1016/j.devcel.2018.05.007
https://doi.org/10.1016/j.devcel.2018.05.007
Autor:
Daniel W. Buster, Cody J. Boese, Natalie A. Hollingsworth, Kevin C. Slep, John M. Ryniawec, Amy E. Byrnes, Gregory C. Rogers, Christopher W. Brownlee, Brian J. Galletta, Tiffany A. McLamarrah, Nasser M. Rusan
Publikováno v:
The Journal of Cell Biology
Centriole duplication is tightly regulated throughout the cell cycle to ensure one duplication event per centriole. McLamarrah et al. show that a stepwise pattern of Ana2 phosphorylation by Plk4 facilitates proper centriole duplication.
Polo-lik
Polo-lik
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c97db2e34e63568e08259d73af6a42f6
Autor:
Carey J. Fagerstrom, Rodrigo X. Guillen, Nasser M. Rusan, Gregory C. Rogers, Timothy L. Megraw, Christopher W. Brownlee, Brian J. Galletta, Dorothy A. Lerit
Publikováno v:
Molecular Biology of the Cell
Pericentrin (PLP) is a centrosomal protein required for organizing pericentriolar material. It requires interaction with calmodulin (CaM) for proper centrosome targeting both in vitro and in vivo. In addition, the PLP-CaM interaction is critical for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::045b37bd24f0488573c6a986b896b6cb
https://doi.org/10.1091/mbc.e13-10-0617
https://doi.org/10.1091/mbc.e13-10-0617
Autor:
Christopher W. Brownlee, Rebecca Heald
Publikováno v:
Cell. 176:805-815.e8
Early embryogenesis is accompanied by reductive cell divisions requiring that subcellular structures adapt to a range of cell sizes. The interphase nucleus and mitotic spindle scale with cell size through both physical and biochemical mechanisms, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f85c796a65a92b8158e70bc83076b9d
https://doi.org/10.1016/j.cell.2018.12.001
https://doi.org/10.1016/j.cell.2018.12.001
Publikováno v:
The Journal of Cell Biology
The PP2A subunit Twins and the SV40 small T antigen, a functional mimic of Twins, counteract Plk4 autophosphorylation, leading to its stabilization and to subsequent centriole amplification.
Centriole duplication is a tightly regulated process t
Centriole duplication is a tightly regulated process t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::327a8a6b3b6298d85e797b9c4db1ddf6
https://doi.org/10.1083/jcb.201107086
https://doi.org/10.1083/jcb.201107086
Publikováno v:
Cellular and molecular life sciences : CMLS. 70(6)
Centrosomes are organelles involved in generating and organizing the interphase microtubule cytoskeleton, mitotic spindles and cilia. At the centrosome core are a pair of centrioles, structures that act as the duplicating elements of this organelle.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cc39b5215f84751e74852133068daad
https://pubmed.ncbi.nlm.nih.gov/22892665
https://pubmed.ncbi.nlm.nih.gov/22892665