Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Christopher W Wasson"'
Autor:
Ethan L Morgan, Molly R Patterson, Emma L Ryder, Siu Yi Lee, Christopher W Wasson, Katherine L Harper, Yigen Li, Stephen Griffin, G Eric Blair, Adrian Whitehouse, Andrew Macdonald
Publikováno v:
PLoS Pathogens, Vol 16, Iss 6, p e1008624 (2020)
Human papillomaviruses (HPV) are a major cause of malignancy worldwide. They are the aetiological agents of almost all cervical cancers as well as a sub-set of other anogenital and head and neck cancers. Hijacking of host cellular pathways is essenti
Externí odkaz:
https://doaj.org/article/11bc911be97c4261b00c98e7510f9fc3
Autor:
Ethan L Morgan, Christopher W Wasson, Lucy Hanson, David Kealy, Ieisha Pentland, Victoria McGuire, Cinzia Scarpini, Nicholas Coleman, J Simon C Arthur, Joanna L Parish, Sally Roberts, Andrew Macdonald
Publikováno v:
PLoS Pathogens, Vol 14, Iss 4, p e1006975 (2018)
Human papillomaviruses (HPV) activate a number of host factors to control their differentiation-dependent life cycles. The transcription factor signal transducer and activator of transcription (STAT)-3 is important for cell cycle progression and cell
Externí odkaz:
https://doaj.org/article/e238124870e24d9a84f1a35422dae093
Autor:
Paolo Sgrò, Cristina Antinozzi, Christopher W. Wasson, Francesco Del Galdo, Ivan Dimauro, Luigi Di Luigi
Publikováno v:
Biology, Vol 13, Iss 10, p 796 (2024)
Muscle tissue is an important target of sex steroids, and particularly, testosterone plays essential roles in muscle cell metabolism. Wide ranges of studies have reported sex differences in basal muscle steroidogenesis, and recently several genes hav
Externí odkaz:
https://doaj.org/article/00fe635cb88545c09ef77e5dec994da9
Autor:
Darren C. Machin, Daniel J. Williamson, Peter Fisher, Victoria J. Miller, Zoe L. P. Arnott, Charlotte M. E. Stevenson, Gemma C. Wildsmith, James F. Ross, Christopher W. Wasson, Andrew Macdonald, Benjamin I. Andrews, Daniel Ungar, W. Bruce Turnbull, Michael E. Webb
Publikováno v:
Toxins, Vol 16, Iss 4, p 194 (2024)
Cholera toxoid is an established tool for use in cellular tracing in neuroscience and cell biology. We use a sortase labeling approach to generate site-specific N-terminally modified variants of both the A2-B5 heterohexamer and B5 pentamer forms of t
Externí odkaz:
https://doaj.org/article/e598648757f8438bb29befaeb6e4b709
Autor:
Christopher W. Wasson, Rebecca L. Ross, Rebecca Wells, Clarissa Corinaldesi, Ioanna Ch. Georgiou, Natalia A. Riobo-Del Galdo, Francesco Del Galdo
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-15 (2020)
Abstract Objectives Systemic sclerosis (SSc) is characterised by tissue fibrosis of the major organs of the body including the skin, lungs and heart. We have previously reported that the lncRNA HOTAIR plays a central role in the activation of SSc myo
Externí odkaz:
https://doaj.org/article/183b5f5be4e0494eacc1b87be0018035
Autor:
Christopher. W. Wasson, Eva. M. Clavane, Rebecca. L. Ross, Gemma Migneco, Cristina Antinozzi, Jane. M. Y. Brown, Luigi Di Luigi, Clive. S. McKimmie, Francesco Del Galdo, Paul. J. Meakin
BackgroundThe beta-amyloid precursor protein cleaving enzyme 1 (BACE1) is well known for its role in the development of Alzheimer’s disease via the generation of β-amyloid. Recent publications, including our own, have demonstrated a role for this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65c1f79584eb3b2ec24beeb008fbb637
https://doi.org/10.1101/2022.12.22.521579
https://doi.org/10.1101/2022.12.22.521579
Autor:
James Scarth, Christopher W Wasson, Molly Patterson, Debra Evans, Diego Barba-Moreno, Holli Carden, Adrian Whitehouse, Jamel Mankouri, Adel Samson, Ethan L Morgan, Andrew Macdonald
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d9d4ec0af1da3ea30af46a30f9dfbe3
https://doi.org/10.15252/rc.2022772870
https://doi.org/10.15252/rc.2022772870
Autor:
James A. Scarth, Christopher W. Wasson, Molly R. Patterson, Debra Evans, Diego Barba-Moreno, Holli Carden, Adrian Whitehouse, Jamel Mankouri, Adel Samson, Ethan L. Morgan, Andrew Macdonald
Persistent infection with high-risk human papillomaviruses (HPVs) is the causal factor in multiple human malignancies, including >99% of cervical cancers and a growing proportion of oropharyngeal cancers. Prolonged expression of the viral oncoprotein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6ef5282b6766e4b721ccfb88bf0c034
https://doi.org/10.1101/2022.09.22.508991
https://doi.org/10.1101/2022.09.22.508991
Autor:
Christopher W. Wasson, Jörg H W Distler, Clarissa Corinaldesi, Rebecca L. Ross, Agne Antanaviciute, Clive S. McKimmie, Francesco Del Galdo, Yasser M. El-Sherbiny, Steve Holmes, Antonio Carriero, Ian M. Carr, Gemma Migneco
Publikováno v:
Annals of the Rheumatic Diseases
ObjectivesPlasmacytoid dendritic cells (pDC) have been implicated in the pathogenesis of autoimmune diseases, such as scleroderma (SSc). However, this has been derived from indirect evidence using ex vivo human samples or mouse pDC in vivo. We have d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::473d00b640768e601885c487760a3d7b
https://doi.org/10.1136/annrheumdis-2020-218439
https://doi.org/10.1136/annrheumdis-2020-218439
Publikováno v:
Rheumatology. 60:4395-4400
Objectives Tissue fibrosis in SSc is driven by active fibroblasts (myofibroblasts). Previous studies have shown the intracellular chloride channel 4 (CLIC4) mediates the activation of cancer-associated fibroblasts. In this study we investigated the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1915ca016fe16e405eaecf4e49aaa71
https://doi.org/10.1093/rheumatology/keaa797
https://doi.org/10.1093/rheumatology/keaa797