Zobrazeno 1 - 10
of 335
pro vyhledávání: '"Christopher W Mcintyre"'
Autor:
Adam Shardlow, Natasha J McIntyre, Nitin V Kolhe, Laura B Nellums, Richard J Fluck, Christopher W McIntyre, Maarten W Taal
Publikováno v:
PLoS Medicine, Vol 17, Iss 7, p e1003163 (2020)
BackgroundTissue advanced glycation end product (AGE) accumulation has been proposed as a marker of cumulative metabolic stress that can be assessed noninvasively by measurement of skin autofluorescence (SAF). In persons on haemodialysis, SAF is an i
Externí odkaz:
https://doaj.org/article/e80884f8bf964817b78bc74f920b4a27
Autor:
Kimia Honarmand, Sabhyata Malik, Conor Wild, Laura E Gonzalez-Lara, Christopher W McIntyre, Adrian M Owen, Marat Slessarev
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215203 (2019)
PurposeTo assess the feasibility of using a widely validated, web-based neurocognitive test battery (Cambridge Brain Sciences, CBS) in a cohort of critical illness survivors.MethodsWe conducted a prospective observational study in two intensive care
Externí odkaz:
https://doaj.org/article/6d187f9c7a0e40be96bb0443a8867019
Autor:
Adam Shardlow, Natasha J McIntyre, Simon D S Fraser, Paul Roderick, James Raftery, Richard J Fluck, Christopher W McIntyre, Maarten W Taal
Publikováno v:
PLoS Medicine, Vol 14, Iss 10, p e1002400 (2017)
BackgroundTo reduce over-diagnosis of chronic kidney disease (CKD) resulting from the inaccuracy of creatinine-based estimates of glomerular filtration rate (GFR), UK and international guidelines recommend that cystatin-C-based estimates of GFR be us
Externí odkaz:
https://doaj.org/article/58b131f97ddc491d94cc5b93b1a30897
Publikováno v:
PLoS Medicine, Vol 13, Iss 9, p e1002128 (2016)
BackgroundChronic kidney disease (CKD) is commonly managed in primary care, but most guidelines have a secondary care perspective emphasizing the risk of end-stage kidney disease (ESKD) and need for renal replacement therapy. In this prospective coho
Externí odkaz:
https://doaj.org/article/78d973519cc84c6ea074bf036293218e
Autor:
Nitin V Kolhe, David Staples, Timothy Reilly, Daniel Merrison, Christopher W Mcintyre, Richard J Fluck, Nicholas M Selby, Maarten W Taal
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132279 (2015)
A recent report has highlighted suboptimal standards of care for acute kidney injury (AKI) patients in England. The objective of this study was to ascertain if improvement in basic standard of care by implementing a care bundle (CB) with interruptive
Externí odkaz:
https://doaj.org/article/7c96e4a1fc2145779aa3b1796bb32970
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e65372 (2013)
Cross-sectional studies in dialysis demonstrate muscle wasting associated with loss of function, increased morbidity and mortality. The relative drivers are poorly understood. There is a paucity of data regarding interval change in muscle in pre-dial
Externí odkaz:
https://doaj.org/article/5b980a3d2f4e4d689d4f3342e5a9e264
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e55444 (2013)
Early chronic kidney disease (CKD) is associated with increased cardiovascular (CV) risk but underlying mechanisms remain uncertain. Arterial stiffness (AS) is associated with increased CV risk in advanced CKD, but it is unclear whether AS is relevan
Externí odkaz:
https://doaj.org/article/989a0d3acd2549d2974f36c324db3893
Autor:
Logan R. Van Nynatten, Michael R. Miller, Maitray A. Patel, Mark Daley, Guido Filler, Sigrun Badrnya, Markus Miholits, Brian Webb, Christopher W. McIntyre, Douglas D. Fraser
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Acute and chronic kidney disease continues to confer significant morbidity and mortality in the clinical setting. Despite high prevalence of these conditions, few validated biomarkers exist to predict kidney dysfunction. In this study, we ut
Externí odkaz:
https://doaj.org/article/e0badcdf9b7d4abe999b40d86cbb7ae5
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34699 (2012)
BackgroundBody Mass Index (BMI) as a marker of obesity is an established risk factor for chronic kidney disease (CKD) and cardiovascular disease (CVD). However, BMI can overestimate obesity. Anthropomorphic measurements that include central fat depos
Externí odkaz:
https://doaj.org/article/28325390fd564353869b496c1ec44275
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e40209 (2012)
Background/objectivesTranslocated endotoxin derived from intestinal bacteria is a driver of systemic inflammation and oxidative stress. Severe endotoxaemia is an underappreciated, but characteristic finding in haemodialysis (HD) patients, and appears
Externí odkaz:
https://doaj.org/article/184bccc7445f444d821ef9cc5133951f