Zobrazeno 1 - 10
of 489
pro vyhledávání: '"Christopher W Mcintyre"'
Autor:
Logan R. Van Nynatten, Michael R. Miller, Maitray A. Patel, Mark Daley, Guido Filler, Sigrun Badrnya, Markus Miholits, Brian Webb, Christopher W. McIntyre, Douglas D. Fraser
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Acute and chronic kidney disease continues to confer significant morbidity and mortality in the clinical setting. Despite high prevalence of these conditions, few validated biomarkers exist to predict kidney dysfunction. In this study, we ut
Externí odkaz:
https://doaj.org/article/e0badcdf9b7d4abe999b40d86cbb7ae5
Autor:
Jarrin D. Penny, Lisa Hur, Fabio R. Salerno, Dickson Wong, M. Hussain Jan, Christopher W. McIntyre
Publikováno v:
Frontiers in Nephrology, Vol 3 (2023)
IntroductionThe life-sustaining treatment of hemodialysis (HD) induces recurrent and cumulative systemic circulatory stress resulting in cardiovascular injury. These recurrent insults compound preexisting cardiovascular sequalae leading to the develo
Externí odkaz:
https://doaj.org/article/494896e6527d4a7c9c8146cacae6681b
Autor:
Sandrine Lemoine, Jarrin Penny, Douglas D. Fraser, Fabio R. Salerno, Justin Dorie, Tanya Tamasi, Robert Arntfield, Andrew House, Marat Slessarev, Christopher W. McIntyre
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Severe COVID-19 infection results in significant immune dysregulation resulting from excessive recruitment and activation of neutrophils. The aim of this study was to confirm feasibility, initial safety and detect signal of efficacy of a non
Externí odkaz:
https://doaj.org/article/5636309efec8404a896dbcf2701c727d
Autor:
Christopher W. McIntyre
Publikováno v:
Kidney and Dialysis, Vol 2, Iss 4, Pp 534-536 (2022)
The choice of dialysate sodium concentration remains amongst the most crucial and difficult to address challenges, in the care of hemodialysis (HD) patients. Our understanding of the determinants of sodium transport, as well as the consequences of ge
Externí odkaz:
https://doaj.org/article/1185c7b0b8b844a3bfb2efb2df48c47d
Publikováno v:
Journal of Clinical Medicine, Vol 12, Iss 13, p 4381 (2023)
Sodium imbalance is a hallmark of chronic kidney disease (CKD). Excess tissue sodium in CKD is associated with hypertension, inflammation, and cardiorenal disease. Sodium magnetic resonance imaging (23Na MRI) has been increasingly utilized in CKD cli
Externí odkaz:
https://doaj.org/article/a82a44340812451aba0992ff49745049
Autor:
Jarrin D. Penny, Patricia Jarosz, Fabio R. Salerno, Sandrine Lemoine, Christopher W. McIntyre
Publikováno v:
Kidney Medicine, Vol 3, Iss 6, Pp 992-1002.e1 (2021)
Rationale & Objective: Current hemodialysis (HD) treatments have limited ability to clear larger-molecular-weight uremic toxins. Retention is associated with increased symptom burden, low health-related quality of life (HRQoL), and high mortality. Im
Externí odkaz:
https://doaj.org/article/70e08ba02bb6477ca5679032dee60861
Autor:
Stephanie N. Dixon, Jessica M. Sontrop, Ahmed Al-Jaishi, Lauren Killin, Christopher W. McIntyre, Sierra Anderson, Amit Bagga, Derek Benjamin, Peter Blake, P. J. Devereaux, Eduard Iliescu, Arsh Jain, Charmaine E. Lok, Gihad Nesrallah, Matthew J. Oliver, Sanjay Pandeya, Manish M. Sood, Paul Tam, Ron Wald, Michael Walsh, Merrick Zwarenstein, Amit X. Garg
Publikováno v:
Canadian Journal of Kidney Health and Disease, Vol 8 (2021)
Background: Major Outcomes with Personalized Dialysate TEMPerature (MyTEMP) is a 4-year cluster-randomized clinical trial comparing the effect of using a personalized, temperature-reduced dialysate protocol versus a dialysate temperature of 36.5°C o
Externí odkaz:
https://doaj.org/article/3a508a0c53dc42b68879b8cc65be7eb8
Autor:
Sanjay R. Kharche, Sandrine Lemoine, Tanya Tamasi, Lisa Hur, Aaron So, Christopher W. McIntyre
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Background: Moderate therapeutic hypothermia (TH) is a well-recognized cardio-protective strategy. The instillation of fluid into the peritoneum provides an opportunity to deliver moderate hypothermia as primary prevention against cardiovascular even
Externí odkaz:
https://doaj.org/article/eca3827ace0b452dbd07ea598ce204b8
Publikováno v:
Kidney Medicine, Vol 3, Iss 6, Pp 1100-1101 (2021)
Externí odkaz:
https://doaj.org/article/6d2e67f011ec42738df90d8dc75cfd30
Autor:
Jermiah J. Joseph, Clara Sun, Ting-Yim Lee, Daniel Goldman, Sanjay R. Kharche, Christopher W. McIntyre
Publikováno v:
Applied Sciences, Vol 12, Iss 9, p 4281 (2022)
Background. The treatment of coronary stenosis is decided by performing high risk invasive surgery to generate the fractional flow reserve diagnostics index, a ratio of distal to proximal pressures in respect of coronary atherosclerotic plaques. Non-
Externí odkaz:
https://doaj.org/article/987f3b76647e4a54b419a40a266e4c15