Detection of soluble ST2 in human follicular fluid and luteinized granulosa cells.

Autor: Jennifer H Southcombe, Nathalie Lédée, Sophie Perrier d'Hauterive, Karen Turner, Tim Child, James V Snider, Christopher W G Redman, Ian L Sargent, Ingrid Granne

Publikováno v: PLoS ONE, Vol 8, Iss 9, p e74385 (2013)

Follicular fluid (FF) contains various cytokines that are involved with folliculogenesis, some of which have been shown to be associated with oocyte quality and the implantation potential of a resulting embryo. Several IL-1 family members have previo

Externí odkaz: https://doaj.org/article/300dfd10b1dd40b296c8064bc5c09b15

Syncytiotrophoblast microvesicles released from pre-eclampsia placentae exhibit increased tissue factor activity.

Autor: Chris Gardiner, Dionne S Tannetta, Carol A Simms, Paul Harrison, Christopher W G Redman, Ian L Sargent

Publikováno v: PLoS ONE, Vol 6, Iss 10, p e26313 (2011)

Pre-eclampsia is a complication of pregnancy associated with activation of coagulation. It is caused by the placenta, which sheds increased amounts of syncytiotrophoblast microvesicles (STBM) into the maternal circulation. We hypothesized that STBM c

Externí odkaz: https://doaj.org/article/9c116e99c0aa425a8860e04746ef6a0a

Downregulation of caveolin-1 enhances fusion of human BeWo choriocarcinoma cells.

Autor: Gavin P Collett, Elizabeth A Linton, Christopher W G Redman, Ian L Sargent

Publikováno v: PLoS ONE, Vol 5, Iss 5, p e10529 (2010)

Fusion of placental villous cytotrophoblasts with the overlying syncytiotrophoblast is essential for the maintenance of successful pregnancy, and disturbances in this process have been implicated in pathological conditions such as pre-eclampsia and i

Externí odkaz: https://doaj.org/article/c997ba222b514d30986dc4347efc017e

Diagnostic Biomarkers in Women With Suspected Preeclampsia in a Prospective Multicenter Study

Autor: Dilly O. C. Anumba, Nigel Simpson, Melanie Griffin, Lucy C Chappell, Jenny Myers, Paul T. Seed, Andrew Shennan, Jason Waugh, Lucy Mackillop, Christopher W. G. Redman, Louise C. Kenny, Robyn A. North, Susan Duckworth

Publikováno v: Duckworth, S, Griffin, M, Seed, P T, North, R, Myers, J, Mackillop, L, Simpson, N, Waugh, J, Anumba, D, Kenny, L C, Redman, C W G, Shennan, A H & Chappell, L C 2016, ' Diagnostic Biomarkers in Women With Suspected Preeclampsia in a Prospective Multicenter Study ', Obstetrics and Gynecology . https://doi.org/10.1097/AOG.0000000000001508

To evaluate 47 biomarkers (selected from the current medical literature), in isolation or in combination with placental growth factor (PlGF), to determine the need for delivery within 14 days, in women presenting with suspected preterm preeclampsia.M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ace6652f4fb62a467ba95b1eac5dce3
https://kclpure.kcl.ac.uk/en/publications/53f5aab3-9de6-40f3-acc8-b87e88d093fd

Multicolor flow cytometry and nanoparticle tracking analysis of extracellular vesicles in the plasma of normal pregnant and pre-eclamptic women

Autor: Rebecca A, Dragovic, Jennifer H, Southcombe, Dionne S, Tannetta, Christopher W G, Redman, Ian L, Sargent

Publikováno v: Biology of reproduction. 89(6)

Excessive release of syncytiotrophoblast extracellular vesicles (STBMs) from the placenta into the maternal circulation may contribute to the systemic inflammation that is characteristic of pre-eclampsia (PE). Other intravascular cells types (platele

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cc3ca9807bb35ec857babf9c05daf55e
https://pubmed.ncbi.nlm.nih.gov/24258213