Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Christopher W, Cutler"'
Autor:
Erivan S. Ramos-Junior, Shantiece Dawson, Weston Ryan, Braden Clinebell, Rogelio Serrano-Lopez, Marsha Russell, Rylee Brumbaugh, Roger Zhong, Jussara Gonçalves Fernandes, Luciana M. Shaddox, Christopher W. Cutler, Ana Carolina Morandini
Publikováno v:
Frontiers in Oral Health, Vol 4 (2023)
IntroductionPeriodontitis is an immune-mediated inflammatory disease affecting almost half of the adult population and is the leading cause of tooth loss in the United States. The role of extracellular nucleotide signaling including nucleotide metabo
Externí odkaz:
https://doaj.org/article/b7340b8b064b4693b55054241403f4a7
Autor:
Nathalie Paladines, Shantiece Dawson, Weston Ryan, Rogelio Serrano-Lopez, Regina Messer, Yuqing Huo, Christopher W. Cutler, Erivan S. Ramos-Junior, Ana Carolina Morandini
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionFibroblasts are the dominant stromal cells in the gingival lamina propria with a well-established relevance in regulation of inflammation, and in innate immunity. This is exemplified by their hypersecretion of CXCL8, enhancing leukocyte i
Externí odkaz:
https://doaj.org/article/64e3b579a21b43a4984b51d62dc991ce
Publikováno v:
Pathogens, Vol 12, Iss 9, p 1180 (2023)
The active form of vitamin D is the hormonally active 1,25(OH)2D3 (Vit D) vitamin, which plays an important role in bone biology and host immunity. The vitamin D receptor (VDR) is a nuclear ligand-dependent transcription factor expressed by many cell
Externí odkaz:
https://doaj.org/article/9812401750724f048d26d4c75aa1276c
Autor:
Christopher W. Cutler, Gill Diamond
Publikováno v:
Frontiers in Oral Health, Vol 3 (2022)
Externí odkaz:
https://doaj.org/article/9e831fec288249308cb249a19cf32cbd
Autor:
Ranya Elsayed, Mahmoud Elashiry, Yutao Liu, Ahmed El-Awady, Mark Hamrick, Christopher W. Cutler
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Periodontitis is a disease of ageing or inflammaging, and is comorbid with other more severe age-related chronic diseases. With advanced age comes an increase in accumulation of senescent cells that release soluble and insoluble pro-inflammatory fact
Externí odkaz:
https://doaj.org/article/2fb017f7ad194a94bc4c7f7f05195eb2
Autor:
Mahmoud Elashiry, Ranya Elsayed, Mohamed M. Elashiry, Mohammad H. Rashid, Roxan Ara, Ali S. Arbab, Ahmed R. Elawady, Mark Hamrick, Yutao Liu, Wenbo Zhi, Rudolf Lucas, Jose Vazquez, Christopher W. Cutler
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Dendritic cell (DC)-derived exosomes (DC EXO), natural nanoparticles of endosomal origin, are under intense scrutiny in clinical trials for various inflammatory diseases. DC EXO are eobiotic, meaning they are well-tolerated by the host; moreover, the
Externí odkaz:
https://doaj.org/article/588c763cc47243608e927a4739406756
Autor:
Mahmoud Elashiry, Mohamed M. Elashiry, Ranya Elsayed, Mythily Rajendran, Carol Auersvald, Rana Zeitoun, Mohammad H. Rashid, Roxan Ara, Mohamed M. Meghil, Yutao Liu, Ali S. Arbab, Roger M. Arce, Mark Hamrick, Mohammed Elsalanty, Marshall Brendan, Rafal Pacholczyk, Christopher W. Cutler
Publikováno v:
Journal of Extracellular Vesicles, Vol 9, Iss 1 (2020)
Chronic bone degenerative diseases represent a major threat to the health and well-being of the population, particularly those with advanced age. This study isolated exosomes (EXO), natural nano-particles, from dendritic cells, the “directors” of
Externí odkaz:
https://doaj.org/article/264daa790bda47be9967099735a239ce
Publikováno v:
Pathogens, Vol 11, Iss 3, p 328 (2022)
Porphyromonas gingivalis (P. gingivalis) is a unique pathogen implicated in severe forms of periodontitis (PD), a disease that affects around 50% of the US population. P. gingivalis is equipped with a plethora of virulence factors that it uses to exp
Externí odkaz:
https://doaj.org/article/c50dcf661bed47f885bf1339befbc201
Publikováno v:
Cells, Vol 11, Iss 1, p 115 (2021)
Immune therapeutic exosomes, derived exogenously from dendritic cells (DCs), the ‘directors’ of the immune response, are receiving favorable safety and tolerance profiles in phase I and II clinical trials for a growing number of inflammatory and
Externí odkaz:
https://doaj.org/article/bd82a524ebd743aca89ea3bb65fdc636
Autor:
Mohamed M. Meghil, Omnia K. Tawfik, Mahmoud Elashiry, Mythilypriya Rajendran, Roger M. Arce, David J. Fulton, Patricia V. Schoenlein, Christopher W. Cutler
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
As fundamental processes of immune homeostasis, autophagy, and apoptosis must be maintained to mitigate risk of chronic inflammation and autoimmune diseases. Periodontitis is a chronic inflammatory disease characterized by oral microbial dysbiosis, a
Externí odkaz:
https://doaj.org/article/6ea3cb09dc904a14a12b499acabe386f