Congenital hypoplastic bone marrow failure associated with a de novo partial deletion of the MECOM gene at 3q26.2

Autor: Eigil Kjeldsen, Christopher Veigaard, Henrik Hasle, Anni Aggerholm

Publikováno v: Kjeldsen, E, Veigaard, C, Aggerholm, A & Hasle, H 2018, ' Congenital hypoplastic bone marrow failure associated with a de novo partial deletion of the MECOM gene at 3q26.2 ', Gene, vol. 656, pp. 86-96 . https://doi.org/10.1016/j.gene.2018.02.061

Congenital hypoplastic bone marrow failure is a rare condition in neonates. The genetics and mechanisms behind are largely obscure. Here we characterize a neonate presenting with congenital thrombocytopenia and anemia. During the first 2–4 weeks af

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2de7b3699a7f2b81b1f060df5e4ca046
https://pubmed.ncbi.nlm.nih.gov/29496554

Extreme hyperleukocytosis in a pediatric T-ALL patient with a rare translocation, t(7;19)(q35;p13), and submicroscopic deletions at 4q25, 7q33 and 10q23

Autor: Anni Aggerholm, Henrik Hasle, Christopher Veigaard, Eigil Kjeldsen

Publikováno v: Leukemia Research Reports
Veigaard, C, Aggerholm, A, Hasle, H & Kjeldsen, E 2013, ' Extreme hyperleukocytosis in a pediatric T-ALL patient with a rare translocation, t(7;19)(q35;p13), and submicroscopic deletions at 4q25, 7q33 and 10q23 ', Leukemia Research Reports, vol. 3, no. 1, pp. 4-7 . https://doi.org/10.1016/j.lrr.2013.09.004
Leukemia Research Reports, Vol 3, Iss 1, Pp 4-7 (2014)

Although childhood T-cell acute lymphoblastic leukemia (T-ALL) is a high-risk disease the outcome can vary considerably. The varying outcomes suggest that unrecognized factors may contribute to disease progression. We report on a 2-year-old T-ALL pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cb3caa729a1911123ef4debed2b93f7

Identification of a Minimal Functional Linker in Human Topoisomerase I by Domain Swapping with Cre Recombinase

Autor: Rikke Frøhlich, Christopher Veigaard, Sissel Juul, Marianne Smedegaard Hede, Maria Vinther, Felicie F. Andersen, Maria Bjerre Nielsen

Publikováno v: Hougaard, R F, Juul, S, Vinther, M, Veigaard, C, Hede, M S & Andersen, F F 2008, ' Identification of a minimal functional linker in human topoisomerase I by domain swapping with Cre recombinase ', Biochemistry, vol. 47, no. 27, pp. 7127-7136 . https://doi.org/10.1021/bi800031k

Cellular forms of type IB topoisomerases distinguish themselves from their viral counterparts and the tyrosine recombinases to which they are closely related by having rather extensive N-terminal and linker domains. The functions and necessity of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5266d1708f3a3a7f06f84264514376d9
https://doi.org/10.1021/bi800031k

DOCK4 deletion at 7q31.1 in a de novo acute myeloid leukemia with a normal karyotype

Autor: Eigil Kjeldsen, Christopher Veigaard

Publikováno v: Kjeldsen, E & Veigaard, C 2013, ' DOCK4 deletion at 7q31.1 in a de novo acute myeloid leukemia with a normal karyotype ', Cellular oncology (Dordrecht), vol. 36, no. 5, pp. 395-403 . https://doi.org/10.1007/s13402-013-0145-5

Acute myeloid leukemia with a normal karyotype (NK-AML) has been assigned to an intermediate prognostic risk group. However, there is a marked variability in outcome within this group of AML, suggesting a significant biological and molecular heteroge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d23972898415fc74978ea1f591f4ac0
https://pure.au.dk/portal/da/publications/dock4-deletion-at-7q311-in-a-de-novo-acute-myeloid-leukemia-with-a-normal-karyotype(b0126ecb-a3f3-4882-a014-7bff71d9c3e6).html

Assembly and structural analysis of a covalently closed nano-scale DNA cage

Autor: Christopher Veigaard, Jørn Koch, Birgitta R. Knudsen, Bjarne Knudsen, Bernt Guldbrandtsen, Anni H. Andersen, Göran Karlsson, Marianne Smedegaard Hede, John L. Rubinstein, Cristiano L. P. Oliveira, Felicie F. Andersen, Sissel Juul, Dinna Krüger, Robert McKenna, Jan Skov Pedersen, Mavis Agbandje-McKenna, Rikke Frøhlich, Jörg Bungert

Publikováno v: Nucleic Acids Research
Andersen, F F, Knudsen, B, Oliveira, C L P D, Hougaard, R F, Krüger, D, Bungert, J, Agbandje-McKenna, M, McKenna, R, Jensen, S J, Veigaard, C, Koch, J, Rubinstein, J L, Guldbrandtsen, B, Hede, M S, Karlsson, G, Andersen, A H, Pedersen, J S & Knudsen, B R 2008, ' Assembly and structural analysis of a covalently closed nano-scale DNA cage ', Nucleic Acids Research, vol. 36, no. 4, pp. 1113-1119 . https://doi.org/10.1093/nar/gkm1124

The inherent properties of DNA as a stable polymer with unique affinity for partner molecules determined by the specific Watson-Crick base pairing makes it an ideal component in self-assembling structures. This has been exploited for decades in the d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::035eadf72625d4d7ed4c302d1507d283
https://pubmed.ncbi.nlm.nih.gov/18096620