Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Christopher V Dayas"'
Autor:
Alex Reichenbach, Rachel E Clarke, Romana Stark, Sarah Haas Lockie, Mathieu Mequinion, Harry Dempsey, Sasha Rawlinson, Felicia Reed, Tara Sepehrizadeh, Michael DeVeer, Astrid C Munder, Juan Nunez-Iglesias, David C Spanswick, Randall Mynatt, Alexxai V Kravitz, Christopher V Dayas, Robyn Brown, Zane B Andrews
Publikováno v:
eLife, Vol 11 (2022)
Agouti-related peptide (AgRP) neurons increase motivation for food, however, whether metabolic sensing of homeostatic state in AgRP neurons potentiates motivation by interacting with dopamine reward systems is unexplored. As a model of impaired metab
Externí odkaz:
https://doaj.org/article/ce133815579f4f688a056bc9c76ade0a
Autor:
Kelly M Smith, Tyler J Browne, Olivia C Davis, A Coyle, Kieran A Boyle, Masahiko Watanabe, Sally A Dickinson, Jacqueline A Iredale, Mark A Gradwell, Phillip Jobling, Robert J Callister, Christopher V Dayas, David I Hughes, Brett A Graham
Publikováno v:
eLife, Vol 8 (2019)
Nociceptive information is relayed through the spinal cord dorsal horn, a critical area in sensory processing. The neuronal circuits in this region that underpin sensory perception must be clarified to better understand how dysfunction can lead to pa
Externí odkaz:
https://doaj.org/article/e0cd9725113d49e9aa0bf5e1f78d7155
Autor:
Tyler J. Browne, Kelly M. Smith, Mark A. Gradwell, Christopher V. Dayas, Robert J. Callister, David I. Hughes, Brett A. Graham
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-22 (2024)
Abstract Spinal projection neurons (PNs) are defined by long axons that travel from their origin in the spinal cord to the brain where they relay sensory information from the body. The existence and function of a substantial axon collateral network,
Externí odkaz:
https://doaj.org/article/ec93f78f34ca4384b30c43e37a0ef70a
Autor:
Erin Jane Campbell, Stephanie M Watters, Ihssane eZouikr, Deborah M Hodgson, Christopher V Dayas
Publikováno v:
Frontiers in Neuroscience, Vol 9 (2015)
Exposure to early life physiological stressors, such as infection, is thought to contribute to the onset of psychopathology in adulthood. In animal models, injections of the bacterial immune challenge, lipopolysaccharide (LPS), during the neonatal pe
Externí odkaz:
https://doaj.org/article/58d9fa35cdda49f295a7ef9a5158aea6
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 8 (2014)
Recent work has established that the paraventricular thalamus (PVT) is a central node in the brain reward-seeking pathway. This role is likely mediated in part through the dense projections to the PVT from hypothalamic peptide transmitter systems suc
Externí odkaz:
https://doaj.org/article/8e4a99efe4924ae9a87202cda71b35fd
Autor:
Morgan H James, Erin Jane Campbell, Frederick Rohan Walker, Douglas W Smith, Heather N Richardson, Deborah M Hodgson, Christopher V Dayas
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 8 (2014)
Early life stress (ELS) is a known antecedent for the development of mood disorders such as depression. Orexin neurons drive arousal and motivated behaviors in response to stress. We tested the hypothesis that ELS alters orexin system function and le
Externí odkaz:
https://doaj.org/article/dffcc4dfb25e4fcbb866eb75e6b82b58
Publikováno v:
Frontiers in Neuroscience, Vol 8 (2014)
The tight regulation of sleep/wake states is critical for mental and physiological wellbeing. For example, dysregulation of sleep/wake systems predisposes individuals to metabolic disorders such as obesity and psychiatric problems, including depressi
Externí odkaz:
https://doaj.org/article/d98d7c49c09448898e64462549f6500a
Autor:
Ihssane Zouikr, Morgan H James, Erin J Campbell, Vicki L Clifton, Kenneth W Beagley, Christopher V Dayas, Deborah M Hodgson
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e98382 (2014)
Animal and human studies have demonstrated that early pain experiences can produce alterations in the nociceptive systems later in life including increased sensitivity to mechanical, thermal, and chemical stimuli. However, less is known about the imp
Externí odkaz:
https://doaj.org/article/2e6e4a1aa3b94d918804b4048695b435
Autor:
Caitlin S. Mitchell, Erin J. Campbell, Simon D. Fisher, Laura M. Stanton, Nicholas J. Burton, Amy J. Pearl, Gavan P. McNally, Jaideep S. Bains, Tamás Füzesi, Brett A. Graham, Elizabeth E. Manning, Christopher V. Dayas
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Impaired motivational drive is a key feature of depression. Chronic stress is a known antecedent to the development of depression in humans and depressive-like states in animals. Whilst there is a clear relationship between stress and motiva
Externí odkaz:
https://doaj.org/article/e892cfa1b0cc4b1c91328ec5064f90fa
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 7 (2013)
Externí odkaz:
https://doaj.org/article/86d46bdb855341c982ec01dcce2ed04f