Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Christopher T. Winkelmann"'
Autor:
Nancy Chen, David E. Ehmann, Robert Crooker, Katayoun Derakhchan, Xiaodong Fang, Brian Felice, Elizabeth J. Galbreath, Charles Glaus, Hongbo Gu, Yan Huang, Christine Li, Xing Li, Nan Liu, Kathleen Palmieri, Damir Simic, Joseph Sypek, Susan Thompson, Christopher T. Winkelmann, Vivian W. Choi
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 29, Iss , Pp 286-302 (2023)
Mucopolysaccharidosis II (MPS II) is a rare lysosomal storage disease characterized by deficient activity of iduronate-2-sulfatase (I2S), leading to pathological accumulation of glycosaminoglycans (GAGs) in tissues. We used iduronate-2-sulfatase knoc
Externí odkaz:
https://doaj.org/article/b33a6cf79e06450e92ea9144dc1312b7
Autor:
Talakad G. Lohith, Charalambos Kaittanis, Anthony P. Belanger, Shin Hye Ahn, Phil Sandoval, Lawrence Cohen, Girija Rajarshi, Wanida Ruangsiriluk, Rizwana Islam, Christopher T. Winkelmann, Paul McQuade
Publikováno v:
Molecules, Vol 28, Iss 20, p 7144 (2023)
Success of gene therapy relies on the durable expression and activity of transgene in target tissues. In vivo molecular imaging approaches using positron emission tomography (PET) can non-invasively measure magnitude, location, and durability of tran
Externí odkaz:
https://doaj.org/article/a1111645ef52495b89d67a68aa2b1bb8
Autor:
Brian B. Haines, Kimberly A. Bettano, Melissa Chenard, Raquel S. Sevilla, Christopher Ware, Minilik H. Angagaw, Christopher T. Winkelmann, Christopher Tong, John F. Reilly, Cyrille Sur, Weisheng Zhang
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 1, Pp 39-47 (2009)
Two genetically engineered, conditional mouse models of lung tumor formation, K-rasLSL-G12D and K-rasLSL-G12D/p53LSL-R270H, are commonly used to model human lung cancer. Developed by Tyler Jacks and colleagues, these models have been invaluable to st
Externí odkaz:
https://doaj.org/article/3a322bb0516e4a1b9d50a378c2275d32
Autor:
Christopher T. Winkelmann, Said Daibes Figueroa, Tammy L. Rold, Wynn A. Volkert, Timothy J. Hoffman
Publikováno v:
Molecular Imaging, Vol 5 (2006)
Metastatic mouse models of melanoma have been characterized by gross necropsy examination, histopathology, and optical imaging. To determine if the time progression, extent, and metabolism of melanoma metastases could be monitored noninvasively, seri
Externí odkaz:
https://doaj.org/article/8a2f1ed95e97477591d5c9424d63a547
Autor:
Pradip K. Majumder, Peter R. Strack, Giulio F. Draetta, Edwin A. Clark, Christopher Winter, Domenico Coppola, Timothy Yeatman, Carolyn Buser, Raymond E. Gibson, John F. Reilly, Giuseppe Mesiti, Shailendra Patel, Jennifer Tammam, Saverio Giampaoli, Timothy Sullivan, Christopher Ware, Christopher T. Winkelmann, Clay L. Efferson
Supplementary Figures 1-3, Tables 1-2 from Downregulation of Notch Pathway by a γ-Secretase Inhibitor Attenuates AKT/Mammalian Target of Rapamycin Signaling and Glucose Uptake in an ERBB2 Transgenic Breast Cancer Model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69ed2415b597b108860c97ced4978686
https://doi.org/10.1158/0008-5472.22386984
https://doi.org/10.1158/0008-5472.22386984
Autor:
Meera E. Modi, Katayoun Derakhchan, Christopher T. Winkelmann, Elizabeth J. Galbreath, David E. Ehmann
Publikováno v:
Molecular Genetics and Metabolism. 138:107227
Autor:
Kathleen Gabrielson, Polina Sysa-Shah, Claire Lyons, Dmitri Artemov, Catherine A. Foss, Christopher T. Winkelmann, Sébastien Monette
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecea07a85123b42a2add1811322fffff
https://doi.org/10.1016/b978-0-12-821044-4.00007-8
https://doi.org/10.1016/b978-0-12-821044-4.00007-8
Autor:
Rick Adler, Famke Aeffner, Laura E. Armstrong, Dmitri Artemov, Adam D. Aulbach, Bindu M. Bennet, Eric A. Blomme, Brad Bolon, Christopher J. Bowman, Molly Boyle, Alys Bradley, Dino Bradley, Danielle Brown, Pierre R. Bushel, Ellen Cannady, Mark F. Cesta, Curtis Chan, Jennifer A. Chilton, Peter J.M. Clements, Torrie A. Crabbs, Myrtle A. Davis, Sandy Eldridge, Daniela Ennulat, Jeffrey Everitt, Isabel Figueroa, James D. Fikes, Thomas Forest, Catherine A. Foss, John R. Foster, Kathleen Gabrielson, Shayne C. Gad, Kapil Gadkar, Jinping Gan, David Garcia-Tapia, Frank J. Geoly, Wendy G. Halpern, Jerry F. Hardisty, Wanda M. Haschek, Kathleen Marie Heinz-Taheny, Kristi Helke, Lauren E. Himmel, Mark J. Hoenerhoff, Jennifer L. Ingram–Ross, Armando R. Irizarry Rovira, Evan B. Janovitz, Kishore Katyayan, Charlotte M. Keenan, Angela King-Herbert, Steven T. Laing, Lois D. Lehman-McKeeman, Na Li, Calvert Louden, Claire Lyons, Kevin McDorman, Elizabeth McInnes, Lyn Miller Wancket, Sheroy Minocherhomji, Sébastien Monette, James Morrison, Vasanthi Mowat, Sydney Mukaratirwa, Keith Nelson, Arun R. Pandiri, Tracey Papenfuss, Nita Patel, Daniel J. Patrick, Shari A. Price, Deepa B. Rao, James T. Raymond, Jennifer Rojko, Colin G. Rousseaux, Sara F. Santagostino, Aaron Sargeant, Christina Satterwhite, A. Eric Schultze, Vanessa Schumacher, Cheryl Scudamore, Keith R. Shockley, Bhanu P. Singh, David M. Stresser, Polina Sysa-Shah, Debra A. Tokarz, Terry Van Vleet, Matthew A. Wallig, Jin Wang, Cynthia J. Willson, Kristin Lewis Wilson, Christopher T. Winkelmann, Jeffrey C. Wolf, Charles Wood, Daniela Bumbaca Yadav, Mark Zarella
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3831ed61c4599a4d47034bfb7e19d99
https://doi.org/10.1016/b978-0-12-821044-4.01002-5
https://doi.org/10.1016/b978-0-12-821044-4.01002-5
Autor:
Ziying Yin, Jenifer Siegelman, Jin Wang, Taofic Mounajjed, Richard L. Ehman, Jiahui Li, Jingbiao Chen, Vijay H. Shah, Jie Chen, Meng Yin, Rosa Martin-Mateos, Kevin J. Glaser, Xin Lu, Christopher T Winkelmann, Hiroaki Yashiro
Publikováno v:
Alcohol Clin Exp Res
BACKGROUND Magnetic resonance imaging (MRI) and MRI-based elastography (MRE) are the most promising noninvasive techniques in assessing liver diseases. The purpose of this study was to evaluate an advanced multiparametric imaging method for staging d
Autor:
Christopher T. Winkelmann, Rachel Roach, Dangshe Ma, Lindsay King, Mauricio Leal, Mary E. Spilker, Antonio Esparza, Cedo M. Bagi, Parul Gupta, Jo-Ann Wentland, Anand Giddabasappa
Publikováno v:
Oncotarget
// Parul Gupta 1 , Jo-Ann Wentland 2 , Mauricio Leal 2 , Dangshe Ma 3, 6 , Rachel Roach 4 , Antonio Esparza 5 , Lindsay King 2 , Mary E. Spilker 2 , Cedo Bagi 1 , Christopher T. Winkelmann 1 and Anand Giddabasappa 1 1 Global Science and Technology, C