Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Christopher T. Stamper"'
Autor:
Egle Kvedaraite, Magda Lourda, Natalia Mouratidou, Tim Düking, Avinash Padhi, Kirsten Moll, Paulo Czarnewski, Indranil Sinha, Ioanna Xagoraris, Efthymia Kokkinou, Anastasios Damdimopoulos, Whitney Weigel, Olga Hartwig, Telma E. Santos, Tea Soini, Aline Van Acker, Nelly Rahkonen, Malin Flodström Tullberg, Emma Ringqvist, Marcus Buggert, Carl Jorns, Ulrik Lindforss, Caroline Nordenvall, Christopher T. Stamper, David Unnersjö-Jess, Mira Akber, Ruta Nadisauskaite, Jessica Jansson, Niels Vandamme, Chiara Sorini, Marijke Elise Grundeken, Helena Rolandsdotter, George Rassidakis, Eduardo J. Villablanca, Maja Ideström, Stefan Eulitz, Henrik Arnell, Jenny Mjösberg, Jan-Inge Henter, Mattias Svensson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Stromal cells support epithelial cell and immune cell homeostasis and play an important role in inflammatory bowel disease (IBD) pathogenesis. Here, we quantify the stromal response to inflammation in pediatric IBD and reveal subset-specific
Externí odkaz:
https://doaj.org/article/4dc18c7a87ab47da922abb5a03ceaf68
Autor:
Youngchang Kim, Natalia Maltseva, Christine Tesar, Robert Jedrzejczak, Michael Endres, Heng Ma, Haley L. Dugan, Christopher T. Stamper, Changsoo Chang, Lei Li, Siriruk Changrob, Nai-Ying Zheng, Min Huang, Arvind Ramanathan, Patrick Wilson, Karolina Michalska, Andrzej Joachimiak
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108976- (2024)
Summary: Coronavirus nucleocapsid protein (NP) of SARS-CoV-2 plays a central role in many functions important for virus proliferation including packaging and protecting genomic RNA. The protein shares sequence, structure, and architecture with nucleo
Externí odkaz:
https://doaj.org/article/e75293ccbb074ec98180a116ff5e64b9
Autor:
Roser Tachó-Piñot, Christopher T. Stamper, James I. King, Veronika Matei-Rascu, Erin Richardson, Zhi Li, Luke B. Roberts, John W. Bassett, Felipe Melo-Gonzalez, Rémi Fiancette, I-Hsuan Lin, Alexander Dent, Yohsuke Harada, Conor Finlay, Jenny Mjösberg, David R. Withers, Matthew R. Hepworth
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113425- (2023)
Summary: Innate lymphoid cells (ILCs) are tissue-resident effector cells with roles in tissue homeostasis, protective immunity, and inflammatory disease. Group 3 ILCs (ILC3s) are classically defined by the master transcription factor RORγt. However,
Externí odkaz:
https://doaj.org/article/035a6f626dd34570abb60d2053c54a08
Autor:
Siriruk Changrob, Yanbin Fu, Jenna J. Guthmiller, Peter J. Halfmann, Lei Li, Christopher T. Stamper, Haley L. Dugan, Molly Accola, William Rehrauer, Nai-Ying Zheng, Min Huang, Jiaolong Wang, Steven A. Erickson, Henry A. Utset, Hortencia M. Graves, Fatima Amanat, D. Noah Sather, Florian Krammer, Yoshihiro Kawaoka, Patrick C. Wilson
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
ABSTRACT Several severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants have arisen that exhibit increased viral transmissibility and partial evasion of immunity induced by natural infection and vaccination. To address the specific ant
Externí odkaz:
https://doaj.org/article/f1f464f3ca0944edb5a64c1198cdb0c8
Autor:
Lei Li, Haley L. Dugan, Christopher T. Stamper, Linda Yu-Ling Lan, Nicholas W. Asby, Matthew Knight, Olivia Stovicek, Nai-Ying Zheng, Maria Lucia Madariaga, Kumaran Shanmugarajah, Maud O. Jansen, Siriruk Changrob, Henry A. Utset, Carole Henry, Christopher Nelson, Robert P. Jedrzejczak, Daved H. Fremont, Andrzej Joachimiak, Florian Krammer, Jun Huang, Aly A. Khan, Patrick C. Wilson
Publikováno v:
Cell Reports: Methods, Vol 1, Iss 4, Pp 100056- (2021)
Summary: Multimodal advances in single-cell sequencing have enabled the simultaneous quantification of cell surface protein expression alongside unbiased transcriptional profiling. Here, we present LinQ-View, a toolkit designed for multimodal single-
Externí odkaz:
https://doaj.org/article/e699f72a78bd4f8aa796657f3bd5dcb7
Autor:
Jenna J. Guthmiller, Olivia Stovicek, Jiaolong Wang, Siriruk Changrob, Lei Li, Peter Halfmann, Nai-Ying Zheng, Henry Utset, Christopher T. Stamper, Haley L. Dugan, William D. Miller, Min Huang, Ya-Nan Dai, Christopher A. Nelson, Paige D. Hall, Maud Jansen, Kumaran Shanmugarajah, Jessica S. Donington, Florian Krammer, Daved H. Fremont, Andrzej Joachimiak, Yoshihiro Kawaoka, Vera Tesic, Maria Lucia Madariaga, Patrick C. Wilson
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
With the ongoing pandemic, it is critical to understand how natural immunity against SARS-CoV-2 and COVID-19 develops. We have identified that subjects with more severe COVID-19 disease mount a more robust and neutralizing antibody response against S
Externí odkaz:
https://doaj.org/article/795af7997c9f4b069f3284b32db263f4
Autor:
Priscilla S. Briquez, Sherin J. Rouhani, Jovian Yu, Athalia R. Pyzer, Jonathan Trujillo, Haley L. Dugan, Christopher T. Stamper, Siriruk Changrob, Anne I. Sperling, Patrick C. Wilson, Thomas F. Gajewski, Jeffrey A. Hubbell, Melody A. Swartz
Publikováno v:
Science Advances. 8
Patients infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can experience life-threatening respiratory distress, blood pressure dysregulation, and thrombosis. This is thought to be associated with an impaired activity of
Autor:
Marcos C. Vieira, Anna-Karin E. Palm, Christopher T. Stamper, Micah E. Tepora, Khoa D. Nguyen, Tho D. Pham, Scott D. Boyd, Patrick C. Wilson, Sarah Cobey
Antibodies result from the competition of B cell lineages evolving under selection for improved antigen recognition, a process known as affinity maturation. High-affinity antibodies to pathogens such as HIV, influenza, and SARS-CoV-2 are frequently r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1797d4e60f26270faf8a2af2bde99720
https://doi.org/10.1101/2022.09.16.508315
https://doi.org/10.1101/2022.09.16.508315
Autor:
Lei Li, Siriruk Changrob, Yanbin Fu, Olivia Stovicek, Jenna J Guthmiller, Joshua J C McGrath, Haley L Dugan, Christopher T Stamper, Nai-Ying Zheng, Min Huang, Patrick C Wilson
Publikováno v:
Brief Bioinform
Artificial mutagenesis and protein engineering have laid the foundation for antigenic characterization and universal vaccine design for influenza viruses. However, many methods used in this process require manual sequence editing and protein expressi
Autor:
Peter Palese, Anna-Karin E. Palm, Patrick C. Wilson, Marie Van der Wielen, Rahnuma Wahid, Michelle Dickey, Jeffrey T. Guptill, Rong Hai, Chris Gast, Haley L. Dugan, David I. Bernstein, Alicia Solórzano, Abdollah Naficy, Christopher T. Stamper, Monica M. McNeal, Raffael Nachbagauer, Min Gao, Emmanuel B. Walter, Linda Yu-Ling Lan, Randy A. Albrecht, Dustin G. Shaw, Florian Krammer, Micah E. Tepora, Jodi Feser, Heather Wenzel, Megan E Ermler, Jenna J. Guthmiller, D. Freeman, Bruce L Innis, Adolfo García-Sastre, Carine Claeys, Kristen N Buschle, Weina Sun, Teddy John Wohlbold, Carole Henry, Victoria Sutton, Francesco Berlanda-Scorza, Yao-Qing Chen
Publikováno v:
The Lancet. Infectious Diseases
The Lancet. Infectious diseases, vol 20, iss 1
The Lancet. Infectious diseases, vol 20, iss 1
Summary Background Influenza viruses cause substantial annual morbidity and mortality globally. Current vaccines protect against influenza only when well matched to the circulating strains. However, antigenic drift can cause considerable mismatches b