Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Christopher T. Richie"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Cerebral dopamine neurotrophic factor (CDNF) and its close structural relative, mesencephalic astrocyte-derived neurotrophic factor (MANF), are proteins with neurotrophic properties. CDNF protects and restores the function of dopamine (DA) n
Externí odkaz:
https://doaj.org/article/9bbc47d9ff964ed5a4326c26392a0c2d
Autor:
Anna K. Allen, Xiaofei Bai, Edward S. Davis, Amy Fabritius, Aimee Jaramillo-Lambert, Peter A. Kropp, Christopher T. Richie, Jill M. Schumacher, Sanjay Shrestha, Kathryn Stein, Ann K. Corsi
Publikováno v:
Journal of Developmental Biology, Vol 11, Iss 4, p 41 (2023)
The C [...]
Externí odkaz:
https://doaj.org/article/29cafa3d77ab4b26808e2e6ead73222b
Autor:
Maryna Koskela, Susanne Bäck, Vootele Võikar, Christopher T. Richie, Andrii Domanskyi, Brandon K. Harvey, Mikko Airavaara
Publikováno v:
Neurobiology of Disease, Vol 97, Iss , Pp 189-200 (2017)
Drug addiction is a chronic brain disease and drugs of abuse cause long lasting neuroadaptations. Addiction is characterized by the loss of control over drug use despite harmful consequences, and high rates of relapse even after long periods of absti
Externí odkaz:
https://doaj.org/article/52ce1a55f9ca459eb8a0fa172ef269c5
Autor:
Anna-Maija Penttinen, Ilmari Parkkinen, Merja H. Voutilainen, Maryna Koskela, Susanne Bäck, Anna Their, Christopher T. Richie, Andrii Domanskyi, Brandon K. Harvey, Raimo K. Tuominen, Liina Nevalaita, Mart Saarma, Mikko Airavaara
Publikováno v:
Frontiers in Neurology, Vol 9 (2018)
Glial cell line-derived neurotrophic factor (GDNF) is one of the most studied neurotrophic factors. GDNF has two splice isoforms, full-length pre-α-pro-GDNF (α-GDNF) and pre-β-pro-GDNF (β-GDNF), which has a 26 amino acid deletion in the pro-regio
Externí odkaz:
https://doaj.org/article/0e3d168a5c6044e79f9fcb0e3793f8c3
Autor:
Chun-Ting Lee, Raphael M. Bendriem, Abigail A. Kindberg, Lila T. Worden, Melanie P. Williams, Tomas Drgon, Barbara S. Mallon, Brandon K. Harvey, Christopher T. Richie, Rebecca S. Hamilton, Jia Chen, Stacie L. Errico, Shang-Yi A. Tsai, George R. Uhl, William J. Freed
Publikováno v:
Cell Reports, Vol 10, Iss 4, Pp 616-632 (2015)
Human pluripotent stem cell (hPSC) lines exhibit repeated patterns of genetic variation, which can alter in vitro properties as well as suitability for clinical use. We examined associations between copy-number variations (CNVs) on chromosome 17 and
Externí odkaz:
https://doaj.org/article/270a8a7e6811439e9276a9c0231e0f07
Autor:
Ross A. McDevitt, Alix Tiran-Cappello, Hui Shen, Israela Balderas, Jonathan P. Britt, Rosa A.M. Marino, Stephanie L. Chung, Christopher T. Richie, Brandon K. Harvey, Antonello Bonci
Publikováno v:
Cell Reports, Vol 8, Iss 6, Pp 1857-1869 (2014)
The dorsal raphe nucleus (DRN) contains the largest group of serotonin-producing neurons in the brain and projects to regions controlling reward. Although pharmacological studies suggest that serotonin inhibits reward seeking, electrical stimulation
Externí odkaz:
https://doaj.org/article/41d995accc9d4239b4b17a24aba5d06a
Autor:
Mari H. Savolainen, Christopher T. Richie, Brandon K. Harvey, Pekka T. Männistö, Kathleen A. Maguire-Zeiss, Timo T. Myöhänen
Publikováno v:
Neurobiology of Disease, Vol 68, Iss , Pp 1-15 (2014)
The misfolding and aggregation of α-synuclein (aSyn) eventually lead to an accumulation of toxic forms that disturb normal neuronal function and result in cell death. aSyn rich inclusions are seen in Parkinson's disease, dementia with Lewy bodies an
Externí odkaz:
https://doaj.org/article/c7bcb981635d436dbabcfad7192b26e0
Autor:
Jennifer M. Bossert, Carlos A. Mejias-Aponte, Thomas Saunders, Lindsay Altidor, Michael Emery, Ida Fredriksson, Ashley Batista, Sarah M. Claypool, Kiera E. Caldwell, David J. Reiner, Jonathan J. Chow, Matthew Foltz, Vivek Kumar, Audrey Seasholtz, Elizabeth Hughes, Wanda Filipiak, Brandon K. Harvey, Christopher T. Richie, Francois Vautier, Juan L. Gomez, Michael Michaelides, Brigitte L. Kieffer, Stanley J. Watson, Huda Akil, Yavin Shaham
Publikováno v:
The Journal of Neuroscience. 43:1692-1713
The brain µ-opioid receptor (MOR) is critical for the analgesic, rewarding, and addictive effects of opioid drugs. However, in rat models of opioid-related behaviors, the circuit mechanisms of MOR-expressing cells are less known because of a lack of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfe7ae4967be9d95039228d09b7a62b2
https://doi.org/10.1523/jneurosci.2049-22.2023
https://doi.org/10.1523/jneurosci.2049-22.2023
Autor:
Jennifer M. Bossert, Carlos A. Mejias-Aponte, Thomas Saunders, Lindsay Altidor, Michael Emery, Ida Fredriksson, Ashley Batista, Sarah M. Claypool, Kiera E. Caldwell, David J. Reiner, Jonathan J. Chow, Matthew Foltz, Vivek Kumar, Audrey Seasholtz, Elizabeth Hughes, Wanda Filipiak, Brandon K. Harvey, Christopher T. Richie, Francois Vautier, Juan L. Gomez, Michael Michaelides, Brigitte L. Kieffer, Stanley J. Watson, Huda Akil, Yavin Shaham
The brain µ-opioid receptor (MOR) is critical for the analgesic, rewarding, and addictive effects of opioid drugs. However, in rat models of opioid-related behaviors, the circuit mechanisms of MOR-expressing cells are less known because of a lack of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef2d43e95e8230d1fbe7e3799e7f89ec
https://doi.org/10.1101/2022.11.02.514895
https://doi.org/10.1101/2022.11.02.514895
Autor:
Benjamin L Green, Robert R C Grant, Christopher T Richie, Bishwanath Chatterjee, Michelly Sampaio De Melo, Frederic G Barr, Karel Pacak, Sunita K Agarwal, Naris Nilubol
Publikováno v:
Eur J Endocrinol
Introduction Recurrent and metastatic pheochromocytoma (PCC) are rare advanced endocrine neoplasms with limited treatment options. Insight into the pathogenic molecular alterations in patients with advanced PCC can provide therapeutic options for pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5cae221bdd264be8d995e259ebef1b5
https://europepmc.org/articles/PMC9347184/
https://europepmc.org/articles/PMC9347184/