Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Christopher T. Johndrow"'
Autor:
Tony W. Ng, Wakako Furuyama, Ariel S. Wirchnianski, Noemí A. Saavedra-Ávila, Christopher T. Johndrow, Kartik Chandran, William R. Jacobs, Andrea Marzi, Steven A. Porcelli
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Previous studies have demonstrated the efficacy and feasibility of an anti-viral vaccine strategy that takes advantage of pre-existing CD4+ helper T (Th) cells induced by Mycobacterium bovis bacille Calmette-Guérin (BCG) vaccination. This strategy u
Externí odkaz:
https://doaj.org/article/f8873c18c52a478ba7ece8617e9ee5b6
Autor:
Ariel S. Wirchnianski, Anna Z. Wec, Tony W. Ng, Steven A. Porcelli, Kartik Chandran, Hua-Xin Liao, J. Maximilian Fels, Christopher T. Johndrow, Kevin O. Saunders, John Chan, William R. Jacobs
Publikováno v:
The Journal of Immunology. 205:425-437
The continuing emergence of viral pathogens and their rapid spread into heavily populated areas around the world underscore the urgency for development of highly effective vaccines to generate protective antiviral Ab responses. Many established and n
Autor:
Grégoire Lauvau, John Chan, Nazanin Khajoueinejad, Christopher T. Johndrow, Michael F. Goldberg, William R. Jacobs, Noemi Alejandra Saavedra-Avila, Steven A. Porcelli, Jiayong Xu, Betsy C. Herold, Tony W. Ng, Alison J. Johnson, Shajo Kunnath-Velayudhan, John Kim, Pooja Arora, Christopher Petro, Neeraj K. Saini
Publikováno v:
ImmunoHorizons. 3:161-171
During Ag priming, naive CD4+ T cells differentiate into subsets with distinct patterns of cytokine expression that dictate to a major extent their functional roles in immune responses. We identified a subset of CD4+ T cells defined by secretion of I
Autor:
Ulrich D. Kadolsky, Daniel H. Kaplan, Alison J. Johnson, Tony W. Ng, Andrew J. Yates, Steven A. Porcelli, Grégoire Lauvau, Shajo Kunnath-Velayudhan, G. H. Gossel, William R. Jacobs, John Chan, Christopher T. Johndrow, Michael F. Goldberg
Publikováno v:
The Journal of Immunology. 201:3604-3616
Effective subunit vaccines require the incorporation of adjuvants that stimulate cells of the innate immune system to generate protective adaptive immune responses. Pattern recognition receptor agonists are a growing class of potential adjuvants that
Autor:
Liam R. Cox, Amareeta K. Besra, Himanshu Kharkwal, Natacha Veerapen, Gurdyal S. Besra, Alan Howell, Christopher T. Johndrow, Lianjun Zhang, Noemi Alejandra Saavedra-Avila, Peter J. Jervis, Leandro J. Carreño, Elizabeth E. Evans, Steven A. Porcelli, Samantha Rothberg, Alena Donda, Steven C. Almo, Maurice Zauderer, Shalu Sharma Kharkwal, Scott J. Garforth, Jinghang Zhang
Publikováno v:
Cancer Res
CD1d-restricted invariant natural killer T cells (iNKT cells) mediate strong antitumor immunity when stimulated by glycolipid agonists. However, attempts to develop effective iNKT cell agonists for clinical applications have been thwarted by potentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c9e51cc5ecf1296bf2eb078435815ad
https://europepmc.org/articles/PMC8137529/
https://europepmc.org/articles/PMC8137529/
Autor:
Tony W, Ng, Ariel S, Wirchnianski, Anna Z, Wec, J Maximilian, Fels, Christopher T, Johndrow, Kevin O, Saunders, Hua-Xin, Liao, John, Chan, William R, Jacobs, Kartik, Chandran, Steven A, Porcelli
Publikováno v:
J Immunol
The continuing emergence of viral pathogens and their rapid spread into heavily populated areas around the world underscore the urgency for development of highly effective vaccines to generate protective anti-viral antibody responses. Many establishe
Autor:
Steven A. Porcelli, William R. Jacobs, Jiayong Xu, John Chan, Neeraj K. Saini, Michael F. Goldberg, Alison J. Johnson, Tony W. Ng, Christopher T. Johndrow, Shajo Kunnath-Velayudhan
Publikováno v:
The Journal of Immunology. 199:2596-2606
Analysis of Ag-specific CD4+ T cells in mycobacterial infections at the transcriptome level is informative but technically challenging. Although several methods exist for identifying Ag-specific T cells, including intracellular cytokine staining, cel
Autor:
Shajo, Kunnath-Velayudhan, Michael F, Goldberg, Neeraj K, Saini, Tony W, Ng, Pooja, Arora, Christopher T, Johndrow, Noemi Alejandra, Saavedra-Avila, Alison J, Johnson, Jiayong, Xu, John, Kim, Nazanin, Khajoueinejad, Christopher D, Petro, Betsy C, Herold, Gregoire, Lauvau, John, Chan, William R, Jacobs, Steven A, Porcelli
Publikováno v:
ImmunoHorizons
During Ag priming, naive CD4+ T cells differentiate into subsets with distinct patterns of cytokine expression that dictate to a major extent their functional roles in immune responses. We identified a subset of CD4+ T cells defined by secretion of I
Autor:
Bridget Shafit-Zagardo, Christopher T. Johndrow, Dominika Burek, Alex K. Ray, Pablo García de Frutos, Ross C. Gruber, Hillary Guzik
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Growth arrest-specific protein 6 (GAS6) is a soluble agonist of the TYRO3, AXL, MERTK (TAM) family of receptor tyrosine kinases identified to have anti-inflammatory, neuroprotective, and promyelinating properties. During experimental autoimmune encep
Autor:
Shajo, Kunnath-Velayudhan, Michael F, Goldberg, Neeraj K, Saini, Christopher T, Johndrow, Tony W, Ng, Alison J, Johnson, Jiayong, Xu, John, Chan, William R, Jacobs, Steven A, Porcelli
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 199(7)
Analysis of antigen-specific CD4+ T cells in mycobacterial infections at the transcriptome level is informative but technically challenging. While several methods exist for identifying antigen-specific T cells, including intracellular cytokine staini