Making Employee Health Benefits Understandable: The Summary-Plan-Description Failure and How to Fix It

Autor: Christopher Switzer

Publikováno v: SSRN Electronic Journal.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::745da8b9c16157d4d49d59b05ed0bf47
https://doi.org/10.2139/ssrn.4037756

Blood Pressure–Lowering by the Antioxidant Resveratrol Is Counterintuitively Mediated by Oxidation of cGMP-Dependent Protein Kinase

Autor: Oleksandra, Prysyazhna, Kathryn, Wolhuter, Christopher, Switzer, Celio, Santos, Xiaoping, Yang, Steven, Lynham, Ajay M, Shah, Philip, Eaton, Joseph R, Burgoyne

Publikováno v: Circulation
Prysyazhna, O, Wolhuter, K, Switzer, C H, Santos, C, Yang, X, Lynham, S, Shah, A M, Eaton, P & Burgoyne, J 2019, ' Blood pressure-lowering by the antioxidant resveratrol is counterintuitively mediated by oxidation of cGMP-dependent protein kinase ', Circulation, vol. 140, no. 2, pp. 126–137 . https://doi.org/10.1161/CIRCULATIONAHA.118.037398

Supplemental Digital Content is available in the text.
Background: The health-promoting and disease-limiting abilities of resveratrol, a natural polyphenol, has led to considerable interest in understanding the mechanisms of its therapeutic acti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::822b5cae90c65dc55eb80b7a3dd491d6
http://europepmc.org/articles/PMC6635045

Flexible Nucleic Acids (FNAs) as Informational Molecules: Enzymatic Polymerization of fNTPs on DNA Templates and Nonenzymatic Oligomerization of RNA on FNA Templates

Autor: Maryline, Chemama, Christopher, Switzer

Publikováno v: Methods in molecular biology (Clifton, N.J.). 1973

The methodology enabling enzymatic and nonenzymatic information transfer with FNAs is described. This methodology includes the chemical synthesis of fNTPs and fN phosphoramidites, in addition to protocols for the enzymatic and nonenzymatic transfer o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::08111d6e18bd4e7b9b550ce75c6f7adf
https://pubmed.ncbi.nlm.nih.gov/31016705

Flexible Nucleic Acids (FNAs) as Informational Molecules: Enzymatic Polymerization of fNTPs on DNA Templates and Nonenzymatic Oligomerization of RNA on FNA Templates

Autor: Christopher Switzer, Maryline Chemama

Publikováno v: Methods in Molecular Biology ISBN: 9781493992157

The methodology enabling enzymatic and nonenzymatic information transfer with FNAs is described. This methodology includes the chemical synthesis of fNTPs and fN phosphoramidites, in addition to protocols for the enzymatic and nonenzymatic transfer o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8119bc90c867a46d5808ea54e12c19c9
https://doi.org/10.1007/978-1-4939-9216-4_14

Synthesis and Evolution of a Threose Nucleic Acid Aptamer Bearing 7-Deaza-7-Substituted Guanosine Residues

Autor: Randi M. Jimenez, Christopher Switzer, Saikat Bala, Yajun Wang, Hui Mei, John C. Chaput, Cailen M McCloskey, Jen-Yu Liao

Publikováno v: Journal of the American Chemical Society. 140(17)

In vitro selection experiments carried out on artificial genetic polymers require robust and faithful methods for copying genetic information back and forth between DNA and xeno-nucleic acids (XNA). Previously, we have shown that Kod-RI, an engineere

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d742ea9b226c1bdb2853bfac8515e8fa
https://pubmed.ncbi.nlm.nih.gov/29667819