Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Christopher Solis"'
Autor:
Nicole C Woitowich, Sarah R Hengel, Christopher Solis, Tauras P Vilgalys, Joel Babdor, Daniel J Tyrrell
Publikováno v:
eLife, Vol 12 (2024)
Many postdoctoral fellows and scholars who hope to secure tenure-track faculty positions in the United States apply to the National Institutes of Health (NIH) for a Pathway to Independence Award. This award has two phases (K99 and R00) and provides f
Externí odkaz:
https://doaj.org/article/9ebb719046f141549f136c1b138c1b8c
Publikováno v:
AIAA SCITECH 2023 Forum.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0966748826695cca50e7d2e99b1c2ee
https://doi.org/10.2514/6.2023-1885
https://doi.org/10.2514/6.2023-1885
Autor:
Christopher Solis, Elisabeth DiNello, Chad M Warren, Kyle Dittloff, R John Solaro, Brenda Russell
Publikováno v:
Circulation Research. 131
The hypothesis tested is that unloading of mechanical forces affects acetylation, ubiquitination, and phosphorylation of the actin-binding protein α-actinin located in the Z-disc. We applied targeted proteomics to interrogate the post-translational
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::719eae54ff869e513767b6b3d80e0932
https://doi.org/10.1161/res.131.suppl_1.p1058
https://doi.org/10.1161/res.131.suppl_1.p1058
Autor:
Loren Telles, Christopher Solis, Benjamin Urioste, Samuel P. Smith, Steven Lockyer, Nathan A. Pehrson
Publikováno v:
AIAA AVIATION 2021 FORUM.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb2f08f1c3f434c7d27af3a6655f81bf
https://doi.org/10.2514/6.2021-2785
https://doi.org/10.2514/6.2021-2785
Publikováno v:
Biophysical Journal. 108(2)
In cardiac muscle troponin (Tn) and tropomyosin (Tm) associate with filamentous actin (Ac) to provide Ca2+-dependent regulation of contraction. In situ, Ca2+ activation is a highly cooperative process thought to be linked to cooperative structural in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37532c073c0a26bf50e45b49b3d7ba54
Publikováno v:
Biophysical Journal. 108(2)
Cardiac troponin (cTn) is composed of troponins C, I, and T. cTnC is the Ca2+-dependent switch for cardiac muscle contraction. A decrease in calcium activation, and a subsequent decrease in cardiac contractility, has been linked to cardiac diseases s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29db19915ddb10f68f24be13401075b8
Publikováno v:
Biophysical Journal. 106(2)
Troponin is the allosteric sensor for calcium in cardiac muscle. During activation, calcium binds to troponin (Tn), causing a conformational change leading to myofilament activation. We seek to understand the energetics and design principle of the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beba5a8defd851403d83a0912e6950af
Publikováno v:
Biophysical Journal. 106(2)
In cardiac muscle, troponin (Tn) and tropomyosin (Tm) on f-actin (Ac) provide Ca2+-dependent regulation of force development by myosin motors. Ca2+ activation is a highly cooperative process that is thought to be due to cooperative structural interac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2623ce3ae1715fe4dbb07789985fe290
Autor:
Christopher Solís, Walter C. Thompson, James R. Peña, Christopher McDermott-Roe, Paulina Langa, Chad M. Warren, Magdalena Chrzanowska, Beata M. Wolska, R. John Solaro, Pieter Detombe, Paul H. Goldspink
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
In the heart, alternative splicing of the igf-I gene produces two isoforms: IGF-IEa and IGF-IEc, (Mechano-growth factor, MGF). The sequence divergence between their E-domain regions suggests differential isoform function. To define the biological act
Externí odkaz:
https://doaj.org/article/4276e5406b9d47d2af2e397c632f998a
Publikováno v:
Physiological Reports, Vol 10, Iss 5, Pp n/a-n/a (2022)
Abstract Age‐related wild‐type transthyretin amyloidosis (wtATTR) is characterized by systemic deposition of amyloidogenic fibrils of misfolded transthyretin (TTR) in the connective tissue of many organs. In the heart, this leads to age‐related
Externí odkaz:
https://doaj.org/article/569b89e2dd404e4a9bda6e4bf9c80dd8