Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Christopher Silvin"'
Autor:
Yi An, Jun Jeon, Lillian Sun, Adeeb Derakhshan, Jianhong Chen, Sophie Carlson, Hui Cheng, Christopher Silvin, Xinping Yang, Carter Van Waes, Zhong Chen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Head and neck squamous cell carcinomas (HNSCC) induced by human papillomavirus (HPV) have increased recently in the US. However, the distinct alterations of molecules involved in the death pathways and drug effects targeting inhibitor of apo
Externí odkaz:
https://doaj.org/article/d665633856e14a8a985871ecd86fdb93
Autor:
Priya Patel, Lily Sun, Yvette Robbins, Paul E. Clavijo, Jay Friedman, Christopher Silvin, Carter Van Waes, John Cook, James Mitchell, Clint Allen
Publikováno v:
OncoImmunology, Vol 8, Iss 11 (2019)
Tumor cells activate the G2/M cell cycle checkpoint in response to ionizing radiation (IR) and effector immune cell-derived granzyme B to facilitate repair and survival. Wee1 kinase inhibition reverses the ability of tumor cells to pause at G2/M. Her
Externí odkaz:
https://doaj.org/article/8cbfd1442ce944dfbfd24c733814d13e
Autor:
Natalia V Strunnikova, Jennifer Barb, Yuri V Sergeev, Ashwin Thiagarajasubramanian, Christopher Silvin, Peter J Munson, Ian M Macdonald
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8402 (2009)
BACKGROUND: Choroideremia (CHM) is a progressive X-linked retinopathy caused by mutations in the CHM gene, which encodes Rab escort protein-1 (REP-1), an escort protein involved in the prenylation of Rabs. Under-prenylation of certain Rabs, as a resu
Externí odkaz:
https://doaj.org/article/4edb3a831b0f49579175e3cc6f5f3c26
Autor:
Ethan L. Morgan, Carter Van Waes, Zhong Chen, Anthony Saleh, Shaleeka Cornelius, Scott Martin, Pinar Ormanoglu, Clint Allen, Christopher Silvin, Yvette Robbins, Yi An, Paul Clavijo, Angel Huynh, Xinping Yang, Jianghong Chen, Hui Cheng, Ramya Viswanathan, Zhengbo Hu
TNFα is a key mediator of immune and radiotherapy-induced cytotoxicity, but many cancers, including head and neck squamous cell carcinomas (HNSCC), display TNF resistance due to activation of the canonical IKK–NF-κB/RELA pro-survival pathway. How
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05b0105497f9159cedc4287d57ece474
https://doi.org/10.1158/1541-7786.c.6545385.v1
https://doi.org/10.1158/1541-7786.c.6545385.v1
Autor:
Ethan L. Morgan, Carter Van Waes, Zhong Chen, Anthony Saleh, Shaleeka Cornelius, Scott Martin, Pinar Ormanoglu, Clint Allen, Christopher Silvin, Yvette Robbins, Yi An, Paul Clavijo, Angel Huynh, Xinping Yang, Jianghong Chen, Hui Cheng, Ramya Viswanathan, Zhengbo Hu
Supplementary Data from Inhibiting WEE1 and IKK-RELA Crosstalk Overcomes TNFα Resistance in Head and Neck Cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::993be5b635e453803fb85907981fdbac
https://doi.org/10.1158/1541-7786.22527330.v1
https://doi.org/10.1158/1541-7786.22527330.v1
Autor:
Ethan L. Morgan, Carter Van Waes, Zhong Chen, Anthony Saleh, Shaleeka Cornelius, Scott Martin, Pinar Ormanoglu, Clint Allen, Christopher Silvin, Yvette Robbins, Yi An, Paul Clavijo, Angel Huynh, Xinping Yang, Jianghong Chen, Hui Cheng, Ramya Viswanathan, Zhengbo Hu
Supplementary Table from Inhibiting WEE1 and IKK-RELA Crosstalk Overcomes TNFα Resistance in Head and Neck Cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::930e734ad90adfb2a62378081b59af5d
https://doi.org/10.1158/1541-7786.22527324.v1
https://doi.org/10.1158/1541-7786.22527324.v1
Autor:
Ethan L. Morgan, Carter Van Waes, Zhong Chen, Anthony Saleh, Shaleeka Cornelius, Scott Martin, Pinar Ormanoglu, Clint Allen, Christopher Silvin, Yvette Robbins, Yi An, Paul Clavijo, Angel Huynh, Xinping Yang, Jianghong Chen, Hui Cheng, Ramya Viswanathan, Zhengbo Hu
Supplementary Figure from Inhibiting WEE1 and IKK-RELA Crosstalk Overcomes TNFα Resistance in Head and Neck Cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67812188339e9452df9c8ca3f470c035
https://doi.org/10.1158/1541-7786.22527327.v1
https://doi.org/10.1158/1541-7786.22527327.v1
Autor:
Carter Van Waes, Zhong Chen, Christina M. Annunziata, Wendell G. Yarbrough, Xiulan Su, Natalia Issaeva, Christopher Silvin, Jianhong Chen, Paul E. Clavijo, Stephan S. Späth, Hui Cheng, Xinping Yang, Tony Chen, Jialing Zhang
Human papilloma viruses (HPV) are linked to an epidemic increase in oropharyngeal head and neck squamous cell carcinomas (HNSCC), which display viral inactivation of tumor suppressors TP53 and RB1 and rapid regional spread. However, the role of genom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2615ce65aa485e2b0e2221b51049e72f
https://doi.org/10.1158/0008-5472.c.6509871
https://doi.org/10.1158/0008-5472.c.6509871
Autor:
Carter Van Waes, Zhong Chen, Christina M. Annunziata, Wendell G. Yarbrough, Xiulan Su, Natalia Issaeva, Christopher Silvin, Jianhong Chen, Paul E. Clavijo, Stephan S. Späth, Hui Cheng, Xinping Yang, Tony Chen, Jialing Zhang
Supplementary Methods, related references, and Figures: S1, 2 Effects TRAF3 on alternate pathway proteins; S2, Effects TRAF3 on alternate pathway proteins; S3, Effects of TNF/LTB on NF-kB reporter activity and TRAF3 siRNA on alternate pathway; S4, Ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e126caa04855facd651e0047b63c07e
https://doi.org/10.1158/0008-5472.22417545.v1
https://doi.org/10.1158/0008-5472.22417545.v1
Autor:
Carter Van Waes, Zhong Chen, Christina M. Annunziata, Wendell G. Yarbrough, Xiulan Su, Natalia Issaeva, Christopher Silvin, Jianhong Chen, Paul E. Clavijo, Stephan S. Späth, Hui Cheng, Xinping Yang, Tony Chen, Jialing Zhang
Co-occurence of TRAF3 and NF-kappaB pathway alterations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dff227d6ad4b14c0768dd79e3534172
https://doi.org/10.1158/0008-5472.22417548
https://doi.org/10.1158/0008-5472.22417548