Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Christopher S. Spencer"'
Autor:
Jörg Täubel, Ulrike Lorch, Christopher S. Spencer, Anne Freier, Dorothée Camilleri, Dilshat Djumanov, Georg Ferber, Line Marchand, Jean-Pierre Gotteland, Oliver Pohl
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Nolasiban is an orally active oxytocin receptor antagonist being developed to increase the efficiency of assisted reproductive technologies. This study evaluated the pharmacokinetics, pharmacodynamics, and cardiac safety of nolasiban in 45 h
Externí odkaz:
https://doaj.org/article/941c758ff82c46db9ab0bd9fda565dc9
Autor:
Boaz Mendzelevski, Christopher S Spencer, Anne Freier, Dorothée Camilleri, Claus Graff, Jörg Täubel
Publikováno v:
Annals of Noninvasive Electrocardiology, Vol 26, Iss 5, Pp n/a-n/a (2021)
Abstract In clinical trials, traditionally only a limited number of 12‐lead resting electrocardiograms (ECGs) can be recorded and, thus, long intervals may elapse between assessment timepoints and valuable information may be missed during times whe
Externí odkaz:
https://doaj.org/article/9d16201210b542c7bdc8df2938373d87
Autor:
Line Marchand, Georg Ferber, Jean-Pierre Gotteland, Oliver Pohl, Dorothée Camilleri, Anne Freier, Dilshat Djumanov, Christopher S. Spencer, Ulrike Lorch, Jorg Taubel
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports
Nolasiban is an orally active oxytocin receptor antagonist being developed to increase the efficiency of assisted reproductive technologies. This study evaluated the pharmacokinetics, pharmacodynamics, and cardiac safety of nolasiban in 45 healthy wo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e1e0c6bc1df476b79c7c40414930d3c
https://doaj.org/article/941c758ff82c46db9ab0bd9fda565dc9
https://doaj.org/article/941c758ff82c46db9ab0bd9fda565dc9
Autor:
Jorg Taubel, Ulrike Lorch, D. Camilleri, Anne Freier, Christopher S. Spencer, I. Garitaonandia
Vaccination forms a key part of public health strategies to control the spread of SARS-CoV-2 globally. In the UK, two vaccines (BNT162b2-mRNA produced by Pfizer, and ChAdOx-1-S produced by Oxford-AstraZeneca) have been licensed to date, and their adm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b035f571351d59a1b14da83274fc8f9d
https://doi.org/10.1101/2021.04.09.21255200
https://doi.org/10.1101/2021.04.09.21255200
Autor:
Jorg Taubel, Dorothée Camilleri, Boaz Mendzelevski, Anne Freier, Christopher S. Spencer, Claus Graff
Publikováno v:
Annals of Noninvasive Electrocardiology
Mendzelevski, B, Spencer, C S, Freier, A, Camilleri, D, Graff, C & Täubel, J 2021, ' Comparing the consistency of electrocardiogram interval measurements by resting ECG versus 12-lead Holter ', Annals of Noninvasive Electrocardiology, vol. 26, no. 5, e12851 . https://doi.org/10.1111/anec.12851
Annals of Noninvasive Electrocardiology, Vol 26, Iss 5, Pp n/a-n/a (2021)
Mendzelevski, B, Spencer, C S, Freier, A, Camilleri, D, Graff, C & Täubel, J 2021, ' Comparing the consistency of electrocardiogram interval measurements by resting ECG versus 12-lead Holter ', Annals of Noninvasive Electrocardiology, vol. 26, no. 5, e12851 . https://doi.org/10.1111/anec.12851
Annals of Noninvasive Electrocardiology, Vol 26, Iss 5, Pp n/a-n/a (2021)
In clinical trials, traditionally only a limited number of 12‐lead resting electrocardiograms (ECGs) can be recorded and, thus, long intervals may elapse between assessment timepoints and valuable information may be missed during times when patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2262508e36f0fc2a002372238d5b49c0
https://pubmed.ncbi.nlm.nih.gov/33949017
https://pubmed.ncbi.nlm.nih.gov/33949017
Autor:
Ulrike Lorch, Georg Ferber, Mohamed Farouk Chughlay, Anne Freier, Christopher S. Spencer, Cristina Donini, J. Täubel, Myriam El Gaaloul, Stephan Chalon, Simon Coates
Publikováno v:
British journal of clinical pharmacology. 88(1)
Aim Given the increasing emergence of drug resistance in Plasmodium, new antimalarials are urgently required. P218 is an aminopyridine that inhibits dihydrofolate reductase being developed as a malaria chemoprotective drug. Assessing the effect of ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60c8aac533c07e3441afe025a1c27297
https://pubmed.ncbi.nlm.nih.gov/34075612
https://pubmed.ncbi.nlm.nih.gov/34075612
Autor:
Dorothée Camilleri, Anne Freier, Jorg Taubel, Christopher S. Spencer, Samuel Thomas Cole, Ulrike Lorch
To estimate the effectiveness of vaccines in development, a robust mechanism is required to understand immunity, risks of reinfection and measure the immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and how this may ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fd9214a493cc4ab05f2a1403387e380
https://doi.org/10.1101/2020.12.08.20245894
https://doi.org/10.1101/2020.12.08.20245894
Autor:
Anne Freier, Jorg Taubel, William Burch, Avani Patel, Christopher S. Spencer, Jørgen K. Kanters, John Camm, Georg Ferber, Alessandro Mazzetti, Claus Graff, Sara Fernandes
Publikováno v:
Clinical Pharmacology in Drug Development
Täubel, J, Mazzetti, A, Ferber, G, Burch, W, Fernandes, S, Patel, A, Spencer, C S, Freier, A, Graff, C, Kanters, J K & Camm, J 2021, ' A Phase 1 Study to Investigate the Effects of Cortexolone 17α-Propionate, Also Known as Clascoterone, on the QT Interval Using the Meal Effect to Demonstrate ECG Assay Sensitivity ', Clinical Pharmacology in Drug Development, vol. 10, no. 6, pp. 572-581 . https://doi.org/10.1002/cpdd.935
Taubel, J, Mazzetti, A, Ferber, G, Burch, W, Fernandes, S, Patel, A, Spencer, C S, Freier, A, Graff, C, Kanters, J K & Camm, J 2021, ' A Phase 1 Study to Investigate the Effects of Cortexolone 17 alpha-Propionate, Also Known as Clascoterone, on the QT Interval Using the Meal Effect to Demonstrate ECG Assay Sensitivity ', Clinical Pharmacology in Drug Development, vol. 10, no. 6, pp. 572-581 . https://doi.org/10.1002/cpdd.935
Täubel, J, Mazzetti, A, Ferber, G, Burch, W, Fernandes, S, Patel, A, Spencer, C S, Freier, A, Graff, C, Kanters, J K & Camm, J 2021, ' A Phase 1 Study to Investigate the Effects of Cortexolone 17α-Propionate, Also Known as Clascoterone, on the QT Interval Using the Meal Effect to Demonstrate ECG Assay Sensitivity ', Clinical Pharmacology in Drug Development, vol. 10, no. 6, pp. 572-581 . https://doi.org/10.1002/cpdd.935
Taubel, J, Mazzetti, A, Ferber, G, Burch, W, Fernandes, S, Patel, A, Spencer, C S, Freier, A, Graff, C, Kanters, J K & Camm, J 2021, ' A Phase 1 Study to Investigate the Effects of Cortexolone 17 alpha-Propionate, Also Known as Clascoterone, on the QT Interval Using the Meal Effect to Demonstrate ECG Assay Sensitivity ', Clinical Pharmacology in Drug Development, vol. 10, no. 6, pp. 572-581 . https://doi.org/10.1002/cpdd.935
Cortexolone 17 alpha-propionate, also known as clascoterone, is a potent androgen receptor inhibitor intended for the topical treatment of skin diseases associated with androgenic pathway alterations. In nonclinical studies, cortexolone 17 alpha-prop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2e49f38c5b1e05e4513bfe1d56c95fc
https://pubmed.ncbi.nlm.nih.gov/33942574
https://pubmed.ncbi.nlm.nih.gov/33942574
Autor:
Cristina Yunta, Kay Hemmings, Christopher S. Spencer, Lu-Yun Lian, Mark J. I. Paine, Glauber Pacelli Gomes de Lima, Gareth J Lycett
Publikováno v:
Insect Biochemistry and Molecular Biology. 98:25-33
The mosquito Anopheles gambiae is the principal vector for malaria in sub-Saharan Africa. The ability of A. gambiae to transmit malaria is strictly related to blood feeding and digestion, which releases nutrients for oogenesis, as well as substantial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3df40d23cd478d80083996c1319d86d0
https://doi.org/10.1016/j.ibmb.2018.04.010
https://doi.org/10.1016/j.ibmb.2018.04.010
Autor:
Carl Mendoza, Christopher S Spencer, Sean K. Carey, Simon M. Landhäusser, Kevin Devito, Maxwell C. Lukenbach
Publikováno v:
Geological Society of America Abstracts with Programs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b42b402adfc02e377940e4fdc3c71e0
https://doi.org/10.1130/abs/2017am-306440
https://doi.org/10.1130/abs/2017am-306440