Zobrazeno 1 - 10
of 285
pro vyhledávání: '"Christopher S Williams"'
Autor:
Christopher S Williams, Emily J Gallagher, Don C Rockey, Olujimi A Ajijola, Patrick J Hu, Barbara I Kazmierczak, Christopher D Kontos, Jatin M Vyas, Mone Zaidi, Kyu Y Rhee
Publikováno v:
eLife, Vol 12 (2023)
The growing complexities of clinical medicine and biomedical research have clouded the career path for physician-scientists. In this perspective piece, we address one of the most opaque career stage transitions along the physician-scientist career pa
Externí odkaz:
https://doaj.org/article/4ab20f802ff8445ba89b147766a77ea1
Autor:
Christopher S Williams, W Kimryn Rathmell, John M Carethers, Diane M Harper, YM Dennis Lo, Peter J Ratcliffe, Mone Zaidi
Publikováno v:
eLife, Vol 11 (2022)
Physician-scientists have epitomized the blending of deep, rigorous impactful curiosity with broad attention to human health for centuries. While we aspire to prepare all physicians with an appreciation for these skills, those who apply them to push
Externí odkaz:
https://doaj.org/article/e12768452c58472ebfc88547925a05c6
Autor:
Lori A Coburn, Sara N Horst, Rupesh Chaturvedi, Caroline T Brown, Margaret M Allaman, Brooks P Scull, Kshipra Singh, M Blanca Piazuelo, Maithili V Chitnavis, Mallary E Hodges, Michael J Rosen, Christopher S Williams, James C Slaughter, Dawn B Beaulieu, David A Schwartz, Keith T Wilson
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82300 (2013)
Accurate and high-throughput technologies are needed for identification of new therapeutic targets and for optimizing therapy in inflammatory bowel disease. Our aim was to assess multi-analyte protein-based assays of cytokines/chemokines using Lumine
Externí odkaz:
https://doaj.org/article/d4d7f74ea15f44989f08172ba757ae3f
Autor:
Caitlyn W Barrett, Kshipra Singh, Amy K Motley, Mary K Lintel, Elena Matafonova, Amber M Bradley, Wei Ning, Shenika V Poindexter, Bobak Parang, Vishruth K Reddy, Rupesh Chaturvedi, Barbara M Fingleton, Mary K Washington, Keith T Wilson, Sean S Davies, Kristina E Hill, Raymond F Burk, Christopher S Williams
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e67845 (2013)
Selenium (Se) is an essential micronutrient that exerts its functions via selenoproteins. Little is known about the role of Se in inflammatory bowel disease (IBD). Epidemiological studies have inversely correlated nutritional Se status with IBD sever
Externí odkaz:
https://doaj.org/article/ef779befc8d54e5d9a33d60fef5898e8
Autor:
Lori A Coburn, Xue Gong, Kshipra Singh, Mohammad Asim, Brooks P Scull, Margaret M Allaman, Christopher S Williams, Michael J Rosen, M Kay Washington, Daniel P Barry, M Blanca Piazuelo, Robert A Casero, Rupesh Chaturvedi, Zhongming Zhao, Keith T Wilson
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33546 (2012)
Inflammatory bowel disease (IBD), consisting of Crohn's disease and ulcerative colitis (UC), results in substantial morbidity and is difficult to treat. New strategies for adjunct therapies are needed. One candidate is the semi-essential amino acid,
Externí odkaz:
https://doaj.org/article/533feca6ab3b4bd2a33c8baf8209e8b6
Autor:
Caitlyn W Barrett, J Joshua Smith, Lauren C Lu, Nicholas Markham, Kristy R Stengel, Sarah P Short, Baolin Zhang, Aubrey A Hunt, Barbara M Fingleton, Robert H Carnahan, Michael E Engel, Xi Chen, R Daniel Beauchamp, Keith T Wilson, Scott W Hiebert, Albert B Reynolds, Christopher S Williams
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51205 (2012)
Myeloid translocation genes (MTGs) are transcriptional corepressors originally identified in acute myelogenous leukemia that have recently been linked to epithelial malignancy with non-synonymous mutations identified in both MTG8 and MTG16 in colon,
Externí odkaz:
https://doaj.org/article/c68dbf655f9e45e5beff743698a8bd3e
Autor:
Patricia K Russ, Christopher J Pino, Christopher S Williams, David M Bader, Frederick R Haselton, Min S Chang
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e14563 (2011)
Blood vessel epicardial substance (Bves) is a transmembrane adhesion protein that regulates tight junction (TJ) formation in a variety of epithelia. The role of TJs within epithelium extends beyond the mechanical properties. They have been shown to p
Externí odkaz:
https://doaj.org/article/614a757b0fe34dd8bb1b5878af682842
Autor:
Jennifer M. Pilat, Rachel E. Brown, Zhengyi Chen, Nathaniel J. Berle, Adrian P. Othon, M. Washington, Shruti A. Anant, Suguru Kurokawa, Victoria H. Ng, Joshua J. Thompson, Justin Jacobse, Jeremy A. Goettel, Ethan Lee, Yash A. Choksi, Ken S. Lau, Sarah P. Short, Christopher S. Williams
Publikováno v:
Journal of Clinical Investigation.
Autor:
Christopher S. Williams, M. Kay Washington, Frank L. Revetta, Xi Chen, Anthony J. Bilotta, Joshua J. Thompson, Sarah P. Short
Serine threonine kinase 17A (STK17A) is a ubiquitously expressed kinase originally identified as a regulator of apoptosis; however, whether it functionally contributes to colorectal cancer has not been established. Here, we have analyzed STK17A in co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8e2713bc555006fa5522ebb3b5ede81
https://doi.org/10.1158/1541-7786.c.6540327
https://doi.org/10.1158/1541-7786.c.6540327
Autor:
Christopher S. Williams, M. Kay Washington, Frank L. Revetta, Xi Chen, Anthony J. Bilotta, Joshua J. Thompson, Sarah P. Short
Supplemental Figure 1. STK17A expression does not correlate with CRC patient survival. Supplemental Figure 2. Attenuated morphological characteristics observed with decreased STK17A KD. Supplemental Figure 3. STK17A does not affect proliferation or v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4e0a155b7dce27a7737a86c5d8cd623
https://doi.org/10.1158/1541-7786.22512756
https://doi.org/10.1158/1541-7786.22512756