Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Christopher Royer"'
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2506
Nonhuman primate models have an essential role in understanding progressive respiratory disease pathogenesis. Immune and physiologic parameters in the nonhuman primate closely reflect the complexity of human systems and provide an exceptional transla
Publikováno v:
Methods in Molecular Biology ISBN: 9781071623633
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e5ffd5d89bd22a8ec47196241f24488
https://doi.org/10.1007/978-1-0716-2364-0_6
https://doi.org/10.1007/978-1-0716-2364-0_6
Autor:
Shannon Callen, Vernat Exil, Madhavan Nair, Maria Cristina Vazquez Guillamet, Siddappa N. Byrareddy, Neerad C. Mishra, Francois Villinger, Jawad Abukhalaf, Rodrigo Vazquez-Guillamet, Shashi P. Singh, Karin Rudolph, Veena Raizada, Shilpa Buch, Shah S. Hussain, Aryaz Sheybani, Hitendra S. Chand, Hemant S. Agarwal, Christopher Royer, Mohan L. Sopori, Edward G. Barrett
Publikováno v:
Journal of Clinical Investigation. 128:5428-5433
In the era of combined antiretroviral therapy (cART), lung diseases such as chronic bronchitis (CB) and chronic obstructive pulmonary disease (COPD) are common among persons living with HIV (PLWH), particularly smokers. Although smoking is highly pre
Publikováno v:
Sports Medicine and Arthroscopy Review. 24:123-129
Sport-related concussion typically resolves within a few weeks of the injury; however, persistent symptoms have been reported to occur in 10% to 15% of concussions. These ongoing symptoms can cause significant disability and be frustrating for the pa
Autor:
David A. D'Alessandro, Marco Luciani, Thomas H. Hintze, Giulia Borghetti, Ewa Wybieralska, Edward G. Barrett, Khaled Qanud, Maria Cimini, Christopher Royer, Polina Goichberg, Alex Matsuda, Elizabeth Kertowidjojo, Eric Zhang, Yu Zhou, Andrea Sorrentino, Ramaswamy Kannappan, Piero Anversa, Antonio Cannatà, Andrew Webster, Annarosa Leri, Marianna Meo, Oriyanhan Wunimenghe, Marcello Rota, Sergio Signore, Robert E. Michler
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 310:H873-H890
Studies of myocardial aging are complex and the mechanisms involved in the deterioration of ventricular performance and decreased functional reserve of the old heart remain to be properly defined. We have studied a colony of beagle dogs from 3 to 14
Publikováno v:
Immunity, Inflammation and Disease
VTX‐1463 is a selective toll‐like receptor (TLR) 8 agonist that activates a subset of innate immune cells to produce a unique cytokine profile. Delivery of VTX‐1463 via nasal spray may modulate the nasal response in allergic rhinitis. The aim o
Autor:
Anthony A. Estrada, Brian K. Fiske, Karin Rudolph, Paul Galatsis, Stephen A. Ploch, Ellis M, Yu H, Zhizhang Yin, Dianne K. Bryce, Matthew L. Maddess, Antonia F. Stepan, Stefanus J. Steyn, Alok K. Sharma, Christopher Houle, Trost C, Carrie G. Markgraf, Warren D. Hirst, Xiang Wang, Ted Barrett, Marco A. S. Baptista, Todd Sherer, Susan E. Hill, Kalpana M. Merchant, William A. Meier, Matthew E. Kennedy, Hong Mei, Xingrong Liu, Christopher Royer, Reina N. Fuji, Matthew J. Fell, Anastasia G. Henry
Putative gain-of-function mutations in leucine-rich repeat kinase 2 (LRRK2), resulting in increased kinase activity and cellular toxicity, are a leading genetic cause of Parkinson’s disease (PD). Hence, there is strong interest in developing LRRK2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4465f413546427102589d503f22b2061
Autor:
Antonia F. Stepan, Xingrong Liu, Stephen A. Ploch, Anthony A. Estrada, Craig Trost, Christopher Houle, Ted Barrett, Stefan J. Steyn, Christopher Royer, Reina N. Fuji, Paul Galatsis, Anastasia G. Henry, J. Michael Ellis, Zhizhang Yin, Hong Mei, Matthew L. Maddess, Warren D. Hirst, Matthew J. Fell, Matthew E. Kennedy, Hongshi Yu, Susan E. Hill, Kalpana Merchant, Todd Sherer, Elie Needle, Xiang Wang, Carrie G. Markgraf, Marco A. S. Baptista, Alok K. Sharma, Dianne K. Bryce, William A. Meier, Brian K. Fiske, Karin Rudolph, Sakshi Bhargava
Publikováno v:
Science translational medicine. 12(540)
The kinase-activating mutation G2019S in leucine-rich repeat kinase 2 (LRRK2) is one of the most common genetic causes of Parkinson's disease (PD) and has spurred development of LRRK2 inhibitors. Preclinical studies have raised concerns about the saf