Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Christopher Rothwell"'
Autor:
Jason Borawski, Jeremy L. Jenkins, Michelle Lynn Hall, Christopher Rothwell, Catherine Hodgson, Trixie Wagner, Philippe Piechon, Lewis Whitehead, Scott Tria, Pamela Tranter, Anke Bill, Oana Popa, L. Alex Gaither
Publikováno v:
The Journal of Biological Chemistry
Background: The calcium-activated chloride channel ANO1 is highly expressed in cancer. Results: Inhibition of ANO1 activity alone is not sufficient to inhibit cancer cell proliferation, suggesting a novel function of ANO1 protein in cancer. Conclusio
Autor:
Feng Gu, L. Alex Gaither, Chuan Young Ng, Mark Labow, Wei Liu, Christopher Rothwell, Subhash G. Vasudevan, Joanne Y.H. Lim, Aude LeBreton
Publikováno v:
Virology. 389(1-2):8-19
We performed a focused siRNA screen in an A549 dengue type 2 New Guinea C subgenomic replicon cell line (Rluc-replicon) that contains a Renilla luciferase cassette. We found that siRNA mediated knock down of mevalonate diphospho decarboxylase (MVD) i
Autor:
Christopher Rothwell, Douglas Jeffery, Jason Marchese, Nancy Finkel, Heather Hoover, L. Alex Gaither, Jun Li, Jason Borawoski
Publikováno v:
Journal of proteome research. 14(9)
Tumor types can be defined cytologically by their regions of chromosomal amplification, which often results in the high expression of both mRNA and proteins of certain genes contained within the amplicon. An important strategy for defining therapeuti
Autor:
Christopher Rothwell, Hedaythul Choudhury, Larry Alex Gaither, Mariana Oana Popa, Martin Gosling, Pamela Tranter
Publikováno v:
Biophysical Journal. 106(2)
TMEM16A is a calcium activated chloride channel that has been linked to a number of cancer types including prostate, head and neck and esophageal squamous cell carcinomas (ESCC). The TMEM16A gene has been shown to be amplified and overexpressed in ES
Autor:
John Christopher Rothwell
Publikováno v:
Complex Medical Engineering ISBN: 9784431309611
Transcranial magnetic stimulation (TMS) was originally developed as a convenient way of delivering an electrical stimulating pulse across the resistive barrier of the skull and scalp into the brain. The currents induced in the brain are brief, and si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3be590d73631c51f91c93840e100eda
https://doi.org/10.1007/978-4-431-30962-8_42
https://doi.org/10.1007/978-4-431-30962-8_42
Autor:
Mark Labow, Ieuan Clay, Jason Borawski, Louis Wang, Martin Gosling, Stephanie Fitzgerald, Elizabeth George, Christopher Rothwell, Jonathan Baffoe, Sarah Lilley, M. Oana Popa, Mohamed Bentires-Alj, Hedaythul Choudhury, Chantale T. Guy, Kristie Wetzel, Anke Bill, Michael Rebhan, Pichai Raman, L. Alex Gaither, Adrian Britschgi, Stephan Duss, Heike Brinkhaus
Publikováno v:
Cancer Research. 73:LB-205
Genomic alterations are the underlining cause of many human cancers: Amplified and overexpressed genes can drive neoplastic transformation and become essential survival factors for cancer cells. Thus, they represent promising targets for anti-cancer