Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Christopher Racicot"'
Autor:
Alexander Ibraghimov, Daniel Serna, Sahana Bose, Christine Grinnell, Ralf Carrillo, Christopher Chumsae, Gregory M. Preston, Christopher Racicot, Sean McDermott, Alessandro Mora, Patrick Hossler, Boris Labkovsky, David Ouellette, Susanne Scesney
Publikováno v:
mAbs
Protein glycosylation is arguably the paramount post-translational modification on recombinant glycoproteins, and highly cited in the literature for affecting the physiochemical properties and the efficacy of recombinant glycoprotein therapeutics. Gl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c054615bd096120af5bb522a9334acd
https://doi.org/10.1080/19420862.2017.1294295
https://doi.org/10.1080/19420862.2017.1294295
Publikováno v:
Biotechnology Progress. 33:511-522
Mammalian cells in culture rely on sources of carbohydrates to supply the energy requirements for proliferation. In addition, carbohydrates provide a large source of the carbon supply for supporting various other metabolic activities, including the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50370d2098a121dc000936b4fc8a819e
https://doi.org/10.1002/btpr.2429
https://doi.org/10.1002/btpr.2429
Autor:
Patrick Hossler, Yu Zhou, Chris Chumsae, Sean McDermott, Czeslaw Radziejewski, Haly Raharimampionona, Christopher Racicot, Zhaohui Sunny Zhou
Publikováno v:
Analytical chemistry. 87(15)
With the advent of new initiatives to develop chemically defined media, cell culture scientists screen many additives to improve cell growth and productivity. However, the introduction or increase of supplements, typically considered beneficial or pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fa309e34cb7cd4ccf3c26de30bc3d58
https://pubmed.ncbi.nlm.nih.gov/26151084
https://pubmed.ncbi.nlm.nih.gov/26151084
Publikováno v:
Journal of Glycobiology.
Protein glycosylation has had a long storied history towards impacting various structural, functional, and physiochemical properties of the proteins they are attached to. This important and often critical post-translational modification is thus monit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6ed2c075014d2a6ba986437b37b2da7
https://doi.org/10.4172/2168-958x.1000108
https://doi.org/10.4172/2168-958x.1000108
Autor:
Christopher Racicot, Anton V. Manuilov, Patrick Hossler, Christopher Chumsae, Min Wang, Sean McDermott, Kofi Chemfe, Yun (\\'Frank\\') Zhang
Publikováno v:
Biotechnology progress. 31(4)
Charge variants in recombinant proteins are an important series of protein modifications, whose potential role on protein stability, activity, immunogenicity, and pharmacokinetics continues to be studied. Monoclonal antibodies in particular have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::973dd14844da21d92072a1203d5fc863
https://pubmed.ncbi.nlm.nih.gov/25920009
https://pubmed.ncbi.nlm.nih.gov/25920009
Autor:
Sean McDermott, Yu Zhou, Jianmin Li, Ivan R. Correia, Christopher Chumsae, Christopher Racicot, David Ouellette, Joseph G. Matuck, Haly Raharimampionona, Patrick Hossler, John C. Fann
Publikováno v:
Biotechnology progress. 30(6)
Protein glycosylation is an important post-translational modification toward the structure and function of recombinant therapeutics. The addition of oligosaccharides to recombinant proteins has been shown to greatly influence the overall physiochemic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::429aa96be1fa3d973b8ceb78befa69d3
https://pubmed.ncbi.nlm.nih.gov/25132658
https://pubmed.ncbi.nlm.nih.gov/25132658
Improvement of mammalian cell culture performance through surfactant enabled concentrated feed media
Publikováno v:
Biotechnology progress. 29(4)
The design of basal and feed media in mammalian cell culture is paramount towards ensuring acceptable upstream process performance in various operation modes, especially fed-batch culture. Mammalian cell culture media designs have evolved from the cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::357185576052bc2838451672ade15265
https://pubmed.ncbi.nlm.nih.gov/23554412
https://pubmed.ncbi.nlm.nih.gov/23554412