Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Christopher R. West"'
Autor:
Christopher T. Turner, Megan Pawluk, Juliana Bolsoni, Matthew R. Zeglinski, Yue Shen, Hongyan Zhao, Tatjana Ponomarev, Katlyn C. Richardson, Christopher R. West, Anthony Papp, David J. Granville
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Pressure injuries, also known as pressure ulcers, are regions of localized damage to the skin and/or underlying tissue. Repeated rounds of ischemia–reperfusion (I/R) have a major causative role for tissue damage in pressure injury. Ischemi
Externí odkaz:
https://doaj.org/article/1b5989cb91ee444989ea90fcf5e8b58a
Autor:
Mary P. M. Fossey, Shane J. T. Balthazaar, Jordan W. Squair, Alexandra M. Williams, Malihe-Sadat Poormasjedi-Meibod, Tom E. Nightingale, Erin Erskine, Brian Hayes, Mehdi Ahmadian, Garett S. Jackson, Diana V. Hunter, Katharine D. Currie, Teresa S. M. Tsang, Matthias Walter, Jonathan P. Little, Matt S. Ramer, Andrei V. Krassioukov, Christopher R. West
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
By combining experimental models with prospective clinical studies, the authors show that spinal cord injury causes a rapid reduction in cardiac function that precedes structural changes, and that the loss of descending sympathetic control is the maj
Externí odkaz:
https://doaj.org/article/3046aebaccdc45cdbfc10db7ef4000cf
Autor:
Shane J. T. Balthazaar, Tom E. Nightingale, Katharine D. Currie, Christopher R. West, Teresa S. M. Tsang, Matthias Walter, Andrei V. Krassioukov
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Individuals with cervical spinal cord injury (SCI) experience deleterious changes in cardiac structure and function. However, knowledge on when cardiac alterations occur and whether this is dependent upon neurological level of injury remains to be de
Externí odkaz:
https://doaj.org/article/41acda743d974fcfae4c51f68ad85f83
Autor:
Alexandra M. Williams, Neda Manouchehri, Erin Erskine, Keerit Tauh, Kitty So, Katelyn Shortt, Megan Webster, Shera Fisk, Avril Billingsley, Alex Munro, Seth Tigchelaar, Femke Streijger, Kyoung-Tae Kim, Brian K. Kwon, Christopher R. West
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Clinical neuroprotective strategies for acute spinal cord injury (SCI) have largely overlooked the heart. Here the authors show cardiac contractility is immediately impaired in a porcine model of T2 SCI, and cardio-centric treatment with dobutamine o
Externí odkaz:
https://doaj.org/article/6454cf877f514bc6be1f2dab93e7dfb0
Autor:
Gizelle N. K. Fauss, Misty M. Strain, Yung-Jen Huang, Joshua A. Reynolds, Jacob A. Davis, Melissa K. Henwood, Christopher R. West, James W. Grau
Publikováno v:
Frontiers in Systems Neuroscience, Vol 15 (2021)
Pain (nociceptive) input soon after spinal cord injury (SCI) expands the area of tissue loss (secondary injury) and impairs long-term recovery. Evidence suggests that nociceptive stimulation has this effect because it promotes acute hemorrhage. Disru
Externí odkaz:
https://doaj.org/article/bae7fa69f13842bba99acc0bfe7f04df
Autor:
Cameron M. Gee, Melissa A. Lacroix, Trent Stellingwerff, Erica H. Gavel, Heather M. Logan-Sprenger, Christopher R. West
Publikováno v:
Frontiers in Rehabilitation Sciences, Vol 2 (2021)
The twenty-first century has seen an increase in para-sport participation and the number of research publications on para-sport and the para-athlete. Unfortunately, the majority of publications are case reports/case series or study single impairment
Externí odkaz:
https://doaj.org/article/1607d5230b5a4a209e0b244eaca03bff
Autor:
Kathryn A. Harman, Kathryn M. DeVeau, Jordan W. Squair, Christopher R. West, Andrei V. Krassioukov, David S. K. Magnuson
Publikováno v:
Physiological Reports, Vol 9, Iss 15, Pp n/a-n/a (2021)
Abstract Hemodynamic instability and cardiovascular (CV) dysfunction are hallmarks of patients living with cervical and high thoracic spinal cord injuries (SCI). Individuals experience bouts of autonomic dysreflexia (AD) and persistent hypotension wh
Externí odkaz:
https://doaj.org/article/2a8e68c1434a4b2797e3bbb7b6e02365
Publikováno v:
Biology, Vol 10, Iss 10, p 1006 (2021)
As primary medical care for spinal cord injury (SCI) has improved over the last decades there are more individuals living with neurologically incomplete (vs. complete) cervical injuries. For these individuals, a number of promising therapies are bein
Externí odkaz:
https://doaj.org/article/7f4bb8943dea4910a1758d3b823e0076
Autor:
Analisa Jia, Lisa Kuramoto, Freda M. Warner, Lisa Liu, Alexandra M. Williams, Annalijn Conklin, Christopher R. West, Jacquelyn J. Cragg
Publikováno v:
The Journal of Spinal Cord Medicine. :1-7
Autor:
Jordan W Squair, Seth Tigchelaar, Kyung-Mee Moon, Jie Liu, Wolfram Tetzlaff, Brian K Kwon, Andrei V Krassioukov, Christopher R West, Leonard J Foster, Michael A Skinnider
Publikováno v:
eLife, Vol 7 (2018)
Spinal cord injury (SCI) is a devastating neurological condition for which there are currently no effective treatment options to restore function. A major obstacle to the development of new therapies is our fragmentary understanding of the coordinate
Externí odkaz:
https://doaj.org/article/8ac6285b6f134484ada4a54b53dcbe6b