Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Christopher R. Ross"'
Publikováno v:
Open Journal of Internal Medicine. :81-94
Inflammation plays a central role in development of cardiovascular pathology, and enhanced understanding of the innate immune response will help direct novel therapeutic strategies to address heart disease. Host defense peptides (HDPs)—hereunder de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ee2a77b7d18da0cbc3de1cef4880e87
https://doi.org/10.4236/ojim.2013.32021
https://doi.org/10.4236/ojim.2013.32021
Publikováno v:
Viral Immunology. 21:303-314
Porcine reproductive and respiratory syndrome virus (PRRSV) is an RNA virus that initiates infection in pulmonary alveolar macrophages (PAMs), elicits weak immune responses, and establishes a persistent infection. To understand the role of dsRNA inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c69ba23a2b8eaeb2ea955cd355d77f89
https://doi.org/10.1089/vim.2008.0042
https://doi.org/10.1089/vim.2008.0042
Autor:
Annika Linde, Christopher R. Ross, Tonatiuh Melgarejo, Elizabeth G. Davis, L. Dib, Frank Blecha
Publikováno v:
Journal of Veterinary Internal Medicine. 22:247-265
Recent years have witnessed a surge in interest directed at innate immune mechanisms. Proper conceptualization of the key elements of innate immunity, however, is still a work in progress, because most research in immunology traditionally has been fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d695e82638ef596550207fd67b3b5c8
https://doi.org/10.1111/j.1939-1676.2007.0038.x
https://doi.org/10.1111/j.1939-1676.2007.0038.x
Publikováno v:
Chemical Biology & Drug Design. 70:154-157
PR-39 is a cathelicidin with antimicrobial properties, which acts as a suppressor of inflammation and exerts a number of additional activities. We investigated for the first time the effect of PR-39 on human cells, by addressing the possible interfer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a5bdc3d2c4327cab1b21e2fb0715f9f
https://doi.org/10.1111/j.1747-0285.2007.00540.x
https://doi.org/10.1111/j.1747-0285.2007.00540.x
Publikováno v:
Mammalian Genome. 17:332-339
Beta-defensins are a major group of mammalian antimicrobial peptides. Although more than 30 beta-defensins have been identified in humans, only one porcine beta-defensin has been reported. In this article we report the identification and initial char
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e035e3ae4d944487fe2a75766752d04
https://doi.org/10.1007/s00335-005-0158-0
https://doi.org/10.1007/s00335-005-0158-0
Publikováno v:
Developmental & Comparative Immunology. 30:357-366
Hepcidin is a liver-expressed iron-regulating hormone that also is an antimicrobial peptide. Here we report the full-length cDNA sequences of porcine hepcidin and liver-expressed antimicrobial peptide-2 (LEAP-2). Porcine hepcidin and LEAP-2 cDNA sequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f27fae63466ecfc5b9dd8ac403209ec
https://doi.org/10.1016/j.dci.2005.06.004
https://doi.org/10.1016/j.dci.2005.06.004
Publikováno v:
Infection and Immunity. 73:7133-7141
Peptidoglycan recognition proteins (PGRPs) are a group of newly identified proteins with emerging functions in mammalian innate immunity. Here we report the identification and characterization of two long isoforms of porcine PGRP. Their complete cDNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85017c6a57852c14511fe88bea38289e
https://doi.org/10.1128/iai.73.11.7133-7141.2005
https://doi.org/10.1128/iai.73.11.7133-7141.2005
Autor:
Frank Blecha, Ling Zheng, Roman R. Ganta, Michael J. Kenney, Bryan G. Helwig, Timothy I. Musch, Ning Lu, Richard J. Fels, Chanran K. Ganta, Christopher R. Ross
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 289:H1683-H1691
We tested the hypothesis that central angiotensin II (ANG II) administration would activate splenic sympathetic nerve discharge (SND), which in turn would alter splenic cytokine gene expression. Experiments were completed in sinoaortic nerve-lesioned
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca674fdd090fa6e755747fb33982d4ad
https://doi.org/10.1152/ajpheart.00125.2005
https://doi.org/10.1152/ajpheart.00125.2005
Publikováno v:
Developmental & Comparative Immunology. 29:1-7
Triggering receptors expressed on myeloid cells (TREM) are a family of activating receptors expressed on neutrophils and monocytes. These receptors are involved in regulation of immunity by inducing the expression of inflammatory cytokines and adhesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::783c4055e193797140ca3d716d6fa5c0
https://doi.org/10.1016/j.dci.2004.05.007
https://doi.org/10.1016/j.dci.2004.05.007
Publikováno v:
Developmental & Comparative Immunology. 28:163-169
The porcine antimicrobial peptide, PR-39, has several activities beyond its function of killing bacteria. Here we report that PR-39 alters macrophage viability by inhibiting apoptosis, which was induced by nutrient depletion, LPS stimulation or campt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b322f5dadb870ede5e2a9e61c09b1fdd
https://doi.org/10.1016/s0145-305x(03)00135-6
https://doi.org/10.1016/s0145-305x(03)00135-6