Výsledky vyhledávání - "Christopher R. O'Dea"

Intestinal Guanylate Cyclase-C mRNA Expression in Duodenum and Colon of Children

Autor: David S. Reasner, Ramesh Boinpally, Benjamin D. Gold, Stavra A. Xanthakos, Hanna Kwak, Madhuja Mallick, Christopher R. O'Dea, Mitchell B. Cohen, Wilmin Bartolini, Taryn Weissman, Pei Ge, Nicholas CaJacob

Publikováno v: Journal of pediatric gastroenterology and nutrition. 73(6)

Guanylate cyclase-C (GC-C) agonists, which increase intestinal secretion and accelerate transit, are used to treat chronic constipation and constipation-predominant irritable bowel syndrome and are being evaluated for pediatric use. Prior studies sug

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::682d005eb569c235939a3006c7dfa6bc
https://pubmed.ncbi.nlm.nih.gov/34508047

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Efficacy and safety of linaclotide for opioid-induced constipation in patients with chronic noncancer pain syndromes from a phase 2 randomized study

Autor: Darren M. Brenner, Susan M. Fox, Patricia D'Astoli, Charles Argoff, David S. Reasner, Wieslaw Bochenek, Christopher R. O'Dea, Brooks D. Cash, Rick Blakesley

Publikováno v: Pain

Supplemental Digital Content is Available in the Text. In patients with chronic noncancer pain and opioid-induced constipation, linaclotide significantly improved stool consistency, straining, abdominal bloating, and treatment satisfaction vs placebo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d034ec8417096fe1ab077ce777b1d6
https://pubmed.ncbi.nlm.nih.gov/32310620

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Targeted Delivery of Linaclotide to Specific Areas of The Intestine Affects Clinical Efficacy in Patients with Irritable Bowel Syndrome with Constipation (IBS-C)

Autor: Paul Chamberlin, Nicholas Omniewski, William D. Chey, Wieslaw Bochenek, Susan M. Fox, Matthew Miller, Ahmad Hashash, Kenneth Tripp, Christopher R. O'Dea, Michael J. Hall, Carolyn S. Higgins, Mark G. Currie

Publikováno v: Gastroenterology. 152:S1314-S1315

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e4119282f46db0ad3a6fa24c179a58a7
https://doi.org/10.1016/s0016-5085(17)34374-3

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The Relationship of Patient-Reported Treatment Satisfaction with Stool Consistency and Frequency in Chronic Idiopathic Constipation (CIC) Patients Treated with Linaclotide or Placebo

Autor: C. Prakash Gyawali, Kenneth Tripp, Christopher R. O'Dea, Darren M. Brenner

Publikováno v: Gastroenterology. 152:S509-S510

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::31d965707b69dc3dbdde5a62f434ae36
https://doi.org/10.1016/s0016-5085(17)31883-8

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875 - Iw-3718, a Novel Gastric-Retentive Bile Acid Sequestrant, Improved Heartburn and Regurgitation Symptoms in Patients with Persistent Gerd Despite PPI Treatment: A Double-Blind, Placebo-Controlled Study

Autor: Nimish Vakil, Lara Lane, David S. Reasner, Michael F. Vaezi, James Z. Shao, Robert S. Mittleman, Yan Chen, Ronnie Fass, Mark G. Currie, Christopher R. O'Dea, Michael J. Hall

Publikováno v: Gastroenterology. 154:S-174

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::057e683f3ead239f851aba060d7b19d0
https://doi.org/10.1016/s0016-5085(18)30995-8

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Evaluation of Daily GI Symptoms in a Phase 2A Study of IW-9179 in Functional Dyspepsia

Autor: Jeffrey M. Johnston, Donald A. Fitch, Christopher R. O'Dea, James Z. Shao, Mark G. Currie, Jan Tack

Publikováno v: American Journal of Gastroenterology. 109:S637-S638

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ef2955267c2ad116ab72b3c0ac9ddadd
https://doi.org/10.14309/00000434-201410002-02197

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