Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Christopher R. MacKay"'
Autor:
Lindsey E. Bazzone, Junji Zhu, Michael King, GuanQun Liu, Zhiru Guo, Christopher R. MacKay, Pyae P. Kyawe, Natasha Qaisar, Joselyn Rojas-Quintero, Caroline A. Owen, Abraham L. Brass, William McDougall, Christina E. Baer, Timothy Cashman, Chinmay M. Trivedi, Michaela U. Gack, Robert W. Finberg, Evelyn A. Kurt-Jones
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Viral myocarditis, an inflammatory disease of the heart, causes significant morbidity and mortality. Type I interferon (IFN)-mediated antiviral responses protect against myocarditis, but the mechanisms are poorly understood. We previously id
Externí odkaz:
https://doaj.org/article/3a421e72f14049aabaa33306c2d34a1f
Autor:
Lindsey E. Bazzone, Michael King, Christopher R. MacKay, Pyae P. Kyawe, Paul Meraner, Daniel Lindstrom, Joselyn Rojas-Quintero, Caroline A. Owen, Jennifer P. Wang, Abraham L. Brass, Evelyn A. Kurt-Jones, Robert W. Finberg
Publikováno v:
mBio, Vol 10, Iss 1 (2019)
ABSTRACT Encephalomyocarditis virus (EMCV) is a picornavirus that produces lytic infections in murine and human cells. Employing a genome-wide CRISPR-Cas9 knockout screen to find host factors required for EMCV infection, we identified a role for ADAM
Externí odkaz:
https://doaj.org/article/0718071866f9446d8c16a518b045e864
Autor:
Roy J Soberman, Christopher R MacKay, Christine A Vaine, Glennice Bowen Ryan, Anna M Cerny, Mikayla R Thompson, Boris Nikolic, Valeria Primo, Peter Christmas, Paul Sheiffele, Lisa Aronov, David M Knipe, Evelyn A Kurt-Jones
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47740 (2012)
The CD200R1:CD200 axis is traditionally considered to limit tissue inflammation by down-regulating pro-inflammatory signaling in myeloid cells bearing the receptor. We generated CD200R1(-/-) mice and employed them to explore both the role of CD200R1
Externí odkaz:
https://doaj.org/article/b89806b6104e487bb5874dc3f2af1e21
Autor:
Jennifer P. Wang, Lindsey E. Bazzone, Christopher R. MacKay, Daniel Lindstrom, Paul Meraner, Abraham L. Brass, Pyae Phyo Kyawe, Robert W. Finberg, Michael King, Joselyn Rojas-Quintero, Evelyn A. Kurt-Jones, Caroline A. Owen
Publikováno v:
mBio
mBio, Vol 10, Iss 1, p e02734-18 (2019)
mBio, Vol 10, Iss 1 (2019)
mBio, Vol 10, Iss 1, p e02734-18 (2019)
mBio, Vol 10, Iss 1 (2019)
Viral myocarditis is a leading cause of death in the United States, contributing to numerous unexplained deaths in people ≤35 years old. Enteroviruses contribute to many cases of human myocarditis. Encephalomyocarditis virus (EMCV) infection causes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f62185745d1ae45a60c4fd9a2817b88
http://europepmc.org/articles/PMC6428755
http://europepmc.org/articles/PMC6428755
Autor:
Bazzone Le, Junling Wang, Pyae Phyo Kyawe, Robert W. Finberg, Joselyn Rojas-Quintero, Evelyn A. Kurt-Jones, Christopher R. MacKay, Daniel Lindstrom, King M, Paul Meraner, Caroline A. Owen, Abraham L. Brass
Encephalomyocarditis virus (EMCV) is a picornavirus that produces lytic infections in murine and human cells. Employing a genome-wide CRISPR-Cas9 knockout screen to find host factors required for EMCV infection, we identified a role for ADAM9 in EMCV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63e1a8f7d659463be1f356b6e2b9a723
https://doi.org/10.1101/491068
https://doi.org/10.1101/491068
Autor:
Katherine J. Seidl, J. Perry Hall, Paulina Wochal, Luke A. J. O'Neill, Aisling Dunne, Lih-Ling Lin, Vijay A. K. Rathinam, Wen Kuang, Thaddeus Carlson, Caio T. Fagundes, Christopher R. MacKay, Mary Collins, Susan Carpenter, Stefan A. Schattgen, Katherine A. Fitzgerald
Publikováno v:
The Journal of Immunology. 193:1911-1919
TLR4 interactor with leucine-rich repeats (TRIL) is a brain-enriched accessory protein that is important in TLR3 and TLR4 signaling. In this study, we generated Tril−/− mice and examined TLR responses in vitro and in vivo. We found a role for TRI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45fcccfe48a6c80228b2142e155f4f75
https://doi.org/10.4049/jimmunol.1302392
https://doi.org/10.4049/jimmunol.1302392
Autor:
Eric Mick, Evelyn A. Kurt-Jones, Milka Koupenova, Katya Ravid, Christopher R. MacKay, Jane E. Freedman, Lea M. Beaulieu, Emelia J. Benjamin, Olga Vitseva
Publikováno v:
Blood. 124(5)
Viral infections have been associated with reduced platelet counts, the biological significance of which has remained elusive. Here, we show that infection with encephalomyocarditis virus (EMCV) rapidly reduces platelet count, and this response is at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5561f47e8b4eb88594b228e3e2c3650
https://pubmed.ncbi.nlm.nih.gov/25082862
https://pubmed.ncbi.nlm.nih.gov/25082862
Dicer is a multifunctional protein that is essential across species for the generation of microRNAs, a function that is highly conserved across the plant and animal kingdoms. Intriguingly, Dicer exhibits antiviral functions in lower organisms includi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::503a072838fd0f6c36bc90b5fc06f048
https://europepmc.org/articles/PMC3932008/
https://europepmc.org/articles/PMC3932008/
Autor:
Boris Nikolic, Paul Sheiffele, Evelyn A. Kurt-Jones, Christine A. Vaine, Glennice Bowen Ryan, Lisa Aronov, Peter Christmas, David M. Knipe, Anna M. Cerny, Valeria Primo, Christopher R. MacKay, Roy J. Soberman, Mikayla R. Thompson
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47740 (2012)
PLoS ONE
PLoS ONE
The CD200R1:CD200 axis is traditionally considered to limit tissue inflammation by down-regulating pro-inflammatory signaling in myeloid cells bearing the receptor. We generated CD200R1(-/-) mice and employed them to explore both the role of CD200R1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f166cf605646bfa8077e550b3fa501fc
http://europepmc.org/articles/PMC3474780?pdf=render
http://europepmc.org/articles/PMC3474780?pdf=render
Autor:
Bazzone, Lindsey E., Zhu, Junji, King, Michael, Liu, GuanQun, Guo, Zhiru, MacKay, Christopher R., Kyawe, Pyae P., Qaisar, Natasha, Rojas-Quintero, Joselyn, Owen, Caroline A., Brass, Abraham L., McDougall, William, Baer, Christina E., Cashman, Timothy, Trivedi, Chinmay M., Gack, Michaela U., Finberg, Robert W., Kurt-Jones, Evelyn A.
Publikováno v:
Nature Communications; 5/16/2024, Vol. 15 Issue 1, p1-14, 14p