Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Christopher R. Loose"'
Autor:
Jared J. Hartsock, Nils Prenzler, Christina L. Runge, Thomas Lenarz, Will Mclean, Jeffrey S. Rosenbloom, Ashley S. Hinton, Steven D. Rauch, René H. Gifford, George Atiee, Alec N. Salt, Susan King, Sam Wilson, Moraye Bear, Jeffrey M. Karp, Christopher R. Loose, Jenna T.J. Herby, Carl Lebel, David L. Lucchino, Lance E. Jackson, Daniel J. Lee, Robert Langer, Athanasia Warnecke, H Schmitt
Publikováno v:
Otology & Neurotology
Objectives There are no approved pharmacologic therapies for chronic sensorineural hearing loss (SNHL). The combination of CHIR99021+valproic acid (CV, FX-322) has been shown to regenerate mammalian cochlear hair cells ex vivo. The objectives were to
Autor:
Michael K Dempsey, Malgorzata S. Cartiera, W. Mark Saltzman, Ayesha N. Khalid, Christopher R Loose, Peter G. Schulam, Michelle C Nantel, Alyssa Siefert
Publikováno v:
Academic Medicine. 94:528-534
The process of translating academic biomedical advances into clinical care improvements is difficult, risky, expensive, and poorly understood. Notably, many clinicians who identify health care problems do not have the time or expertise to solve the p
Publikováno v:
Journal of Orthopaedic Trauma. 28:S28-S31
OBJECTIVES By coupling an antimicrobial release with a highly nonfouling betaine modification on titanium, this approach innovatively addresses the initial bacterial challenge and the longer term biofilm formation on trauma devices. METHODS Titanium
Autor:
Paula T. Hammond, Tanguy My Chau, Christopher R. Loose, Gregory Stephanopoulos, Anita Shukla, Kathleen E. Fleming, Helen F. Chuang
Publikováno v:
Biomaterials. 31:2348-2357
Medical conditions are often exacerbated by the onset of infection caused by hospital dwelling bacteria such as Staphylococcus aureus. Antibiotics taken orally or intravenously can require large and frequent doses, further contributing to the sharp r
Autor:
Sivaprasad Sukavaneshvar, Jeffrey T. Borenstein, Zheng Zhang, Christopher R. Loose, Linda M. Guiney, Raanan A. Miller
Publikováno v:
Lab on a chip. 13(10)
Assembled polydimethylsiloxane microfluidic devices were modified with a sulfobetaine polymer through continuous “tip-to-tip” modification, significantly reducing blood clotting and extending device patency under blood flow. This technology can b
Publikováno v:
Applied spectroscopy. 66(11)
We have developed a rapid, nondestructive analytical method that estimates the thickness of a surface polymer layer with high precision but unknown accuracy using a single attenuated total reflection Fourier transform infrared (ATR FT-IR) measurement
Autor:
Arthur J. Coury, Heather S. Lapp, Laurence A. Roth, Roger S. Smith, Michael Bouchard, Jun Li, Zheng Zhang, Douglas Weaver, Sivaprasad Sukavaneshvar, David L. Lucchino, Christopher R. Loose, Robert Langer, Gregory R. Brotske, John Biggerstaff
Publikováno v:
Science translational medicine. 4(153)
Adherence of proteins, cells, and microorganisms to the surface of venous catheters contributes to catheter occlusion, venous thrombosis, thrombotic embolism, and infections. These complications lengthen hospital stays and increase patient morbidity
Publikováno v:
Contact Lens and Anterior Eye. 36:e26-e27
Publikováno v:
Biotechnology progress. 23(2)
Using protein fusion partners for in vitro translation may increase solubility, assist in purification, or allow detection of small proteins and peptides. Here we show that the molar yield of peptide in a batch reaction may be maximized by optimizing
Publikováno v:
Nature. 443(7113)
Antimicrobial peptides (AmPs) are small proteins that are used by the innate immune system to combat bacterial infection in multicellular eukaryotes. There is mounting evidence that these peptides are less susceptible to bacterial resistance than tra