Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Christopher R. Lea"'
Autor:
Xiaolei Ma, Emily Brinker, Christopher R. Lea, Diane Delmain, Erin D. Chamorro, Douglas R. Martin, Emily C. Graff, Xu Wang
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
IntroductionMicrobial population structures within fecal samples are vital for disease screening, diagnosis, and gut microbiome research. The two primary methods for collecting feline fecal samples are: (1) using a fecal loop, which retrieves a recta
Externí odkaz:
https://doaj.org/article/b631c46a76934454816b0abb2e7fd77e
Autor:
Nathan A. Boucher, Christopher R. Lea, Zachary P W Smothers, Rev John P. Oliver, Fred Volk, Ellen J. Teng, Harold G. Koenig, Nagy A. Youssef, Donna Ames
Publikováno v:
Military Behavioral Health. 7:327-335
The relationship between posttraumatic stress disorder (PTSD) symptom severity and pain is well known in veterans and active duty military (V/ADM). This study examines the buffering effect of relig...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::714f0bda5f144e728d83942e0cbb4861
https://doi.org/10.1080/21635781.2018.1526149
https://doi.org/10.1080/21635781.2018.1526149
Publikováno v:
Journal of Biological Chemistry. 279:44250-44257
Inorganic polyphosphate (polyP) has been identified and measured in human platelets. Millimolar levels (in terms of Pi residues) of short chain polyP were found. The presence of polyP of approximately 70-75 phosphate units was identified by 31P NMR a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34d39e7471070ee4fc8f533c3c9e0994
https://doi.org/10.1074/jbc.m406261200
https://doi.org/10.1074/jbc.m406261200
Autor:
Hyung Jae Lee, John A. Cieslak, Christina M. Szabo, Sayaka Fukura, Robert M. Coates, John M. Sanders, Suraj Sengupta, Yoshihiro Matsumura, Ali Koohang, Eric Oldfield, Timothy C. Loftus, Hiroshi Sagami, Christopher R. Lea, Michael B. Martin
Publikováno v:
Journal of Medicinal Chemistry. 45:2185-2196
We report the inhibition of a human recombinant geranylgeranyl diphosphate synthase (GGPPSase) by 23 bisphosphonates and six azaprenyl diphosphates. The IC50 values range from 140 nM to 690 microM. None of the nitrogen-containing bisphosphonates that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e64643f70a267fbedd3936067be0032
https://doi.org/10.1021/jm010412y
https://doi.org/10.1021/jm010412y
Publikováno v:
The Journal of biological chemistry. 279(49)
Acidocalcisomes are acidic, calcium storage compartments with a H(+) pump located in their membrane that have been described in several unicellular eukaryotes, including trypanosomatid and apicomplexan parasites, algae, and slime molds, and have also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a096b5c8eed842478c8526a9766c44
https://pubmed.ncbi.nlm.nih.gov/15371423
https://pubmed.ncbi.nlm.nih.gov/15371423
Autor:
Simon L. Croft, Zev Tovian, Gary A. Meints, Subhash Ghosh, Ryan M. Flessner, Tomoyoshi Nozaki, Eric Oldfield, Robert G. Kemp, Timothy C. Loftus, Julian M. W. Chan, Seike Kobayashi, Christopher R. Lea, Jared C. Lewis, Iris Bruchhaus, Howard Kendrick
Publikováno v:
Journal of medicinal chemistry. 47(1)
The effects of a series of 102 bisphosphonates on the inhibition of growth of Entamoeba histolytica and Plasmodium falciparum in vitro have been determined, and selected compounds were further investigated for their in vivo activity. Forty-seven comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::522a7054537b125c2395397276ed3e3a
https://pubmed.ncbi.nlm.nih.gov/14695831
https://pubmed.ncbi.nlm.nih.gov/14695831