Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Christopher R. Jamison"'
Autor:
Cong Bi, James Chadwick, Merrill L. Davies, Albert J. DelMonte, Peng Geng, Andrew W. Glace, Rebecca A. Green, John A. Gurak, Matthew W. Haley, Brian L. He, Bahar Inankur, Christopher R. Jamison, Candice L. Joe, Sergei Kolotuchin, Dong Lin, Sha Lou, Jeffrey Nye, Adrian Ortiz, Geoffrey E. Purdum, Victor W. Rosso, Mansi Shah, Eric M. Simmons, Jason M. Stevens, Neil A. Strotman, Yichen Tan, Ling Zhang
Publikováno v:
The Journal of organic chemistry.
The development of a convergent route to the NLRP3 (nucleotide-binding domain and leucine-rich repeat-containing protein 3) agonist BMS-986299 is reported. The synthesis relies on a key Miyaura borylation and a tandem Suzuki-Miyaura coupling between
Publikováno v:
2020 Medicinal Chemistry Reviews ISBN: 9781734427400
2020 Medicinal Chemistry Reviews
2020 Medicinal Chemistry Reviews
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebf0c5623318daab764965672dbc2a47
https://doi.org/10.29200/acsmedchemrev-v55.ch6
https://doi.org/10.29200/acsmedchemrev-v55.ch6
Autor:
Daniel S. Müller, Larry E. Overman, Gregory L. Lackner, Nicholas L. Untiedt, Christopher R. Jamison, André P. Dieskau, Yuriy Slutskyy
Publikováno v:
The Journal of Organic Chemistry
The evolution of a convergent fragment-coupling strategy for the enantioselective total synthesis of trans-clerodane diterpenoids is described. The key bond construction is accomplished by 1,6-addition of a trans-decalin tertiary radical with 4-vinyl
Publikováno v:
Organic Syntheses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::beb516e401856bd48f8c9519b7567b7d
https://doi.org/10.1002/0471264229.os094.13
https://doi.org/10.1002/0471264229.os094.13
Autor:
Yuriy Slutskyy, Peng Zhao, Young Ho Rhee, Juyeol Lee, Christopher R. Jamison, Michelle R. Garnsey, Larry E. Overman
Publikováno v:
Garnsey, Michelle R; Slutskyy, Yuriy; Jamison, Christopher R; Zhao, Peng; Lee, Juyeol; Rhee, Young Ho; et al.(2018). Short Enantioselective Total Syntheses of Cheloviolenes A and B and Dendrillolide C via Convergent Fragment Coupling Using a Tertiary Carbon Radical.. The Journal of organic chemistry, 83(13), 6958-6976. doi: 10.1021/acs.joc.7b02458. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/6vh8n3kv
The development of a convergent fragment coupling strategy for the enantioselective total syntheses of a group of rearranged spongian diterpenoids that harbor the cis-2,8-dioxabicyclo[3.3.0]octan-3-one unit is described. The key bond disconnection re
Autor:
Yuriy Slutskyy, Juyeol Lee, Peng Zhao, Young Ho Rhee, Christopher R. Jamison, Larry E. Overman
Publikováno v:
Journal of the American Chemical Society. 139(21)
A short enantioselective synthesis of 6-substituted cis-2,8-dioxabicyclo[3.3.0]octan-3-ones is described. The pivotal step is coupling of a tertiary radical generated directly from a tertiary alcohol with a 3-chloro-5-alkoxybutenolide. This strategy
Publikováno v:
Jamison, Christopher R; & Overman, Larry E. (2016). Fragment Coupling with Tertiary Radicals Generated by Visible-Light Photocatalysis. ACCOUNTS OF CHEMICAL RESEARCH, 49(8), 1578-1586. doi: 10.1021/acs.accounts.6b00284. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/3vd5d52m
Accounts of chemical research, vol 49, iss 8
Accounts of chemical research, vol 49, iss 8
Convergent synthesis strategies in which a target molecule is prepared by a branched approach wherein two or more complex fragments are combined at a late stage are almost always preferred over a linear approach in which the overall yield of the targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2e268014efa4f1aa5d47d42886d2144
http://www.escholarship.org/uc/item/3vd5d52m
http://www.escholarship.org/uc/item/3vd5d52m
Autor:
Yuriy Slutskyy, Larry E. Overman, David W. C. MacMillan, Christopher R. Jamison, Christopher C. Nawrat
Publikováno v:
ChemInform. 47
Alkyl oxalates are new bench-stable alcohol-activating groups for radical generation under visible light photoredox conditions. Using these precursors, the first net redox-neutral coupling of tertiary and secondary alcohols with electron-deficient al
Autor:
Larry E. Overman, David W. C. MacMillan, Christopher C. Nawrat, Yuriy Slutskyy, Christopher R. Jamison
Publikováno v:
Journal of the American Chemical Society, vol 137, iss 35
Alkyl oxalates are new bench-stable alcohol-activating groups for radical generation under visible light photoredox conditions. Using these precursors, the first net redox-neutral coupling of tertiary and secondary alcohols with electron-deficient al
Publikováno v:
The Journal of Organic Chemistry. 74:405-407
Biphenylation using (Li(THF)(4))(2) x Zr(biphe)(3) of hexabromotriptycenes bearing H (1-H) or Bu (1-Bu) at the bridgeheads gave triptycenes with triphenylene blades. The blades extend both perpendicular and parallel to the 3-fold axis and generate a