Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Christopher R. Heery"'
Autor:
Arun Rajan, Christopher R. Heery, Anish Thomas, Andrew L. Mammen, Susan Perry, Geraldine O’Sullivan Coyne, Udayan Guha, Arlene Berman, Eva Szabo, Ravi A. Madan, Leomar Y. Ballester, Stefania Pittaluga, Renee N. Donahue, Yo-Ting Tsai, Lauren M. Lepone, Kevin Chin, Fiona Ginty, Anup Sood, Stephen M. Hewitt, Jeffrey Schlom, Raffit Hassan, James L. Gulley
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-12 (2019)
Abstract Background Thymic epithelial tumors are PD-L1–expressing tumors of thymic epithelial origin characterized by varying degrees of lymphocytic infiltration and a predisposition towards development of paraneoplastic autoimmunity. PD-1–target
Externí odkaz:
https://doaj.org/article/b66a3a1a163041f19fe2d792850a4a64
Autor:
Marijo Bilusic, Christopher R. Heery, Julie M. Collins, Renee N. Donahue, Claudia Palena, Ravi A. Madan, Fatima Karzai, Jennifer L. Marté, Julius Strauss, Margaret E. Gatti-Mays, Jeffrey Schlom, James L. Gulley
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-8 (2019)
Abstract Background HuMax-IL8 (now known as BMS-986253) is a novel, fully human monoclonal antibody that inhibits interleukin-8 (IL-8), a chemokine that promotes tumor progression, immune escape, epithelial-mesenchymal transition, and recruitment of
Externí odkaz:
https://doaj.org/article/df02368d4e9e4af5bd803ce31f37897d
Autor:
Lauren M. Lepone, Renee N. Donahue, Italia Grenga, Simon Metenou, Jacob Richards, Christopher R. Heery, Ravi A. Madan, James L. Gulley, Jeffrey Schlom
Publikováno v:
Journal of Circulating Biomarkers, Vol 5 (2016)
Recent advances in human immunology have led to the identification of novel immune cell subsets and the biological function of many of these subsets has now been identified. The recent US Food and Drug Administration approval of several immunotherape
Externí odkaz:
https://doaj.org/article/23c30e00abff4bf7bf35e3c9d7b91d1e
Autor:
Christopher R Heery, Beatriz Walter-Rodriguez, Seth M Steinberg, Guinevere Chun, Stephanie A Harmon, Ismail Baris Turkbey, Peter L Choyke, William L Dahut, Peter A Pinto
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
BackgroundClinical trials have shown the ability of therapeutic vaccines to generate immune responses to tumor-associated antigens (TAAs). What is relatively less known is if this translates into immune-cell (IC) infiltration into the tumor microenvi
Externí odkaz:
https://doaj.org/article/8ceb7e3397a141ef99a929661525827a
Autor:
Christopher R Heery, Beatriz Walter-Rodriguez, Seth M Steinberg, Guinevere Chun, Stephanie A Harmon, Ismail Baris Turkbey, Peter L Choyke, William L Dahut, Peter A Pinto
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Externí odkaz:
https://doaj.org/article/973bc578749d4f0d9e9033517e474177
Autor:
Jeffrey Schlom, Christopher R. Heery, Seth M. Steinberg, David J. Liewehr, James W. Hodge, Jo A. Tucker, Benedetto Farsaci, Jennifer L. Marté, Caroline Jochems, Kwong Y. Tsang, Ravi A. Madan, James L. Gulley
PDF file - 43K, Antigen cascade.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3778a0c9ab8ab1bde99ea9a06daf0533
https://doi.org/10.1158/2326-6066.22536953
https://doi.org/10.1158/2326-6066.22536953
Autor:
Al B. Benson, Sharyn Worrall, Keavy McAbee, Anjelica Q. Davis, Nancy Roach, Jill O'Donnell-Tormey, Edward Cha, Rebecca A. Moss, Arvin Yang, Neil H. Segal, Cynthia L. Sears, Wells Messersmith, Christopher H. Lieu, Smitha S. Krishnamurthi, S. Peter Kang, Elizabeth M. Jaffee, Franck Housseau, Stanley R. Hamilton, Richard M. Goldberg, Wolf H. Fridman, Luis A. Diaz, Dustin A. Deming, Emily Chan, Arthur N. Brodsky, Thomas H. Marsilje, Andrea Dwyer, Christopher R. Heery, Michael A. Morse, Vanessa M. Hubbard-Lucey, Dung T. Le
Immunotherapy is rapidly becoming a standard of care for many cancers. However, colorectal cancer had been generally resistant to immunotherapy, despite features in common with sensitive tumors. Observations of substantial clinical activity for check
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fe819a9579ba657dff6e159f30b6a62
https://doi.org/10.1158/2326-6066.c.6548287.v1
https://doi.org/10.1158/2326-6066.c.6548287.v1
Autor:
Al B. Benson, Sharyn Worrall, Keavy McAbee, Anjelica Q. Davis, Nancy Roach, Jill O'Donnell-Tormey, Edward Cha, Rebecca A. Moss, Arvin Yang, Neil H. Segal, Cynthia L. Sears, Wells Messersmith, Christopher H. Lieu, Smitha S. Krishnamurthi, S. Peter Kang, Elizabeth M. Jaffee, Franck Housseau, Stanley R. Hamilton, Richard M. Goldberg, Wolf H. Fridman, Luis A. Diaz, Dustin A. Deming, Emily Chan, Arthur N. Brodsky, Thomas H. Marsilje, Andrea Dwyer, Christopher R. Heery, Michael A. Morse, Vanessa M. Hubbard-Lucey, Dung T. Le
Supplemental Tables 1 and 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::707eae64e6122a01edf458348b5685d3
https://doi.org/10.1158/2326-6066.22536955.v1
https://doi.org/10.1158/2326-6066.22536955.v1
Autor:
James L. Gulley, Jeffrey Schlom, Ravi A. Madan, Philip M. Arlen, William Dahut, Timothy C. Rodell, Italia Grenga, Renee N. Donahue, Jennifer L. Marté, Myrna Rauckhorst, B. Harpreet Singh, Christopher R. Heery
The nuclear transcription factor brachyury has previously been shown to be a strong mediator of the epithelial-to-mesenchymal transition (EMT) in human carcinoma cells and a strong negative prognostic factor in several tumor types. Brachyury is overe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0becb600fac999b1ab9b666f3a79d0d9
https://doi.org/10.1158/2326-6066.c.6548917.v1
https://doi.org/10.1158/2326-6066.c.6548917.v1
Autor:
Jeffrey Schlom, James L. Gulley, Christopher R. Heery, Ravi A. Madan, Nuhad K. Ibrahim, Janet C. Siebert, Brendan Dempsey, Peter S. Kim, Lauren M. Lepone, Italia Grenga, Renee N. Donahue, Benedetto Farsaci
Custom software for the calculation of the peripheral immunoscore.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::879118c8ea48bc0751f287a737d12660
https://doi.org/10.1158/2326-6066.22537612.v1
https://doi.org/10.1158/2326-6066.22537612.v1