Zobrazeno 1 - 10 of 27 pro vyhledávání: '"Christopher R. Harlow"'
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Akademický článek
Targeting lysyl oxidase reduces peritoneal fibrosis.
Autor: Christopher R Harlow, Xuan Wu, Marielle van Deemter, Fiona Gardiner, Craig Poland, Rebecca Green, Sana Sarvi, Pamela Brown, Karl E Kadler, Yinhui Lu, J Ian Mason, Hilary O D Critchley, Stephen G Hillier
Publikováno v: PLoS ONE, Vol 12, Iss 8, p e0183013 (2017)
Abdominal surgery and disease cause persistent abdominal adhesions, pelvic pain, infertility and occasionally, bowel obstruction. Current treatments are ineffective and the aetiology is unclear, although excessive collagen deposition is a consistent
Externí odkaz: https://doaj.org/article/e05ed63c7a5b49d6b351fb6517bf7a40
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2
Assessment of Reproductive Performance and Problems in Crossbred (Holstein Friesian X Zebu) Dairy Cattle in and Around Mekelle, Tigray, Ethiopia
Autor: Alemselam Birhanu Mekonnin, Desalew Tadesse, Simon C. Riley, Gidena Desta, Goitom Gidey, Christopher R. Harlow, Tadesse Gugssa
Publikováno v: Mekonnin, A B, Harlow, C, Gidey, G, Tadesse, D, Desta, G, Gugssa, T & Riley, S 2015, ' Assessment of Reproductive Performance and Problems in Crossbred (Holstein Friesian X Zebu) Dairy Cattle in and Around Mekelle, Tigray, Ethiopia ' vol. 3, no. 3, pp. 94-101 . DOI: 10.11648/j.avs.20150303.14
A cross sectional study was conducted in and around Mekelle, Tigray, Ethiopia from November 2013 to May 2014 with the aims to assess reproductive performance and prevalence of reproductive problems in crossbred (Holstein Friesian x Zebu) dairy cattle
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03ee7b5424fc084acfddc66c501c98e4
https://hdl.handle.net/20.500.11820/fbd52242-b718-428d-9ac5-d57220480c09
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3
Pre-ovulatory Granulosa Cells of Infertile Women with Endometriosis are Less Sensitive to Luteinizing Hormone
Autor: Christopher R. Harlow, David J. Cahill, Peter Wardle
Publikováno v: American Journal of Reproductive Immunology. 49:66-69
Cahill DJ, Harlow CR, Wardle PG. Pre-ovulatory granulosa cells of infertile women with endometriosis are less sensitive to luteinizing hormone. AJRI 2003; 49:66–69 © Blackwell Munksgaard, 2003 PROBLEM: Reduced fertilization rates in women with min
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::421babe7c7798c3a0da14f42240a8f31
https://doi.org/10.1034/j.1600-0897.2003.01156.x
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4
Lysyl Oxidase Gene Expression and Enzyme Activity in the Rat Ovary: Regulation by Follicle-Stimulating Hormone, Androgen, and Transforming Growth Factor-β Superfamily Members in Vitro
Autor: Mick T Rae, Christopher R. Harlow, Lindsay Davidson, Philip C. Trackman, Stephen G. Hillier
Publikováno v: Endocrinology. 144:154-162
Lysyl oxidase (LOX) catalyzes the final enzymatic reaction required for cross-linking of collagen and elastin fibers and therefore has a crucial role in regulating the formation and maintenance of extracellular matrix in the ovary. LOX mRNA is abunda
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c4aa247112a22292f8e0f819f4e15db
https://doi.org/10.1210/en.2002-220652
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5
FSH and TGF-β Superfamily Members Regulate Granulosa Cell Connective Tissue Growth Factor Gene Expressionin Vitroandin Vivo
Autor: Christopher R. Harlow, Lindsay Davidson, Kathleen H. Burns, Martin M. Matzuk, Stephen G. Hillier, Changning Yan
Publikováno v: Endocrinology. 143:3316-3325
Connective tissue growth factor (CTGF) is a heparin-binding growth factor implicated in diverse epithelial cell types as a paracrine regulator of mitosis, angiogenesis, cellular taxis, and remodeling of the extracellular matrix. To understand the pos
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::450e4b559f6aaa80332351ca4e48729b
https://doi.org/10.1210/en.2001-211389
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6
Higher cortisol:cortisone ratios in the preovulatory follicle of completely unstimulated IVF cycles indicate oocytes with increased pregnancy potential
Autor: Christopher R. Harlow, P.J. Wood, David J. Cahill, Julian M. Jenkins, Stephen D. Keay
Publikováno v: Human Reproduction. 17:2410-2414
BACKGROUND: Conception following gonadotrophin-stimulated IVF and embryo transfer has been associated with a higher intrafollicular cortisol:cortisone ratio and decreased metabolism of cortisol to cortisone. The role of glucocorticoids in human oocyt
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e1077b8b89d21df8f825d93d168b11
https://doi.org/10.1093/humrep/17.9.2410
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7
Local estrogen metabolism in epithelial ovarian cancer suggests novel targets for therapy
Autor: Xia, Ren, Xuan, Wu, Stephen G, Hillier, K Scott, Fegan, Hilary O D, Critchley, J Ian, Mason, Sana, Sarvi, Christopher R, Harlow
Publikováno v: The Journal of Steroid Biochemistry and Molecular Biology
Graphical abstract
Highlights • Human ovarian surface epithelium (OSE) and epithelial ovarian cancer (EOC) cells have the capacity for local metabolism of estrogen. • Estrogen is differentially metabolized in OSE and EOC cells, with E2 forma
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c8d953d6fc9916d1c466907d483f3419
https://pubmed.ncbi.nlm.nih.gov/25817828
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9
Thrombospondin-1 inhibits angiogenesis and promotes follicular atresia in a novel in vitro angiogenesis assay
Autor: Hamish M. Fraser, Stephen G. Hillier, Christopher R. Harlow, Samantha A. Garside, Fiona H. Thomas
Publikováno v: Endocrinology. 151(3)
Thrombospondin-1 (TSP-1) is a putative antiangiogenic factor, but its role in regulating physiological angiogenesis is unclear. We have developed a novel in vitro angiogenesis assay to study the effect of TSP-1 on follicular angiogenesis and developm
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8acb7ceef29974bbde651d7f292c86c
https://pubmed.ncbi.nlm.nih.gov/20080874
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10
Glucocorticoid receptor-mediated regulation of MMP9 gene expression in human ovarian surface epithelial cells
Autor: Hilary O. D. Critchley, Michael T. Rae, Stephen G. Hillier, Deborah Price, Christopher R. Harlow
Publikováno v: Fertility and sterility. 92(2)
Objective To obtain proof-of-concept that locally produced anti-inflammatory steroids suppress ovulation-associated extracellular matrix proteases in human ovarian surface epithelial (OSE) cells. Design Primary OSE cell cultures treated with interleu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::729adf2af191da708cc5fab20932637a
https://pubmed.ncbi.nlm.nih.gov/18722610
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