Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Christopher R. Gourley"'
Autor:
Nicholas M. Negretti, Christopher R. Gourley, Prabhat K. Talukdar, Geremy Clair, Courtney M. Klappenbach, Cody J. Lauritsen, Joshua N. Adkins, Michael E. Konkel
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
The pathogen Campylobacter jejuni invades intestinal cells after secreting protein effectors into the host cell cytosol via the flagellum. Here, Negretti et al. show that one of these effectors, CiaD, binds to host protein IQGAP1, thus leading to unc
Externí odkaz:
https://doaj.org/article/a8b8eb06bb7146fe925ceebb8d17162e
Autor:
Nicholas M. Negretti, Geremy Clair, Prabhat K. Talukdar, Christopher R. Gourley, Steven Huynh, Joshua N. Adkins, Craig T. Parker, Colby M. Corneau, Michael E. Konkel
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Major foodborne bacterial pathogens, such as Campylobacter jejuni, have devised complex strategies to establish and foster intestinal infections. For more than two decades, researchers have used immortalized cell lines derived from human intestinal t
Externí odkaz:
https://doaj.org/article/0694950675a1409ab044eba5f886533f
Autor:
Cody J. Lauritsen, Christopher R. Gourley, Geremy Clair, Joshua N. Adkins, Nicholas M. Negretti, Prabhat K. Talukdar, Michael E. Konkel, Courtney M. Klappenbach
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Nature Communications
Campylobacter jejuni is a foodborne pathogen that binds to and invades the epithelial cells lining the human intestinal tract. Maximal invasion of host cells by C. jejuni requires cell binding as well as delivery of the Cia proteins (Campylobacter in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74b2a70c5b011a8fd7facd7f81916e6f
https://doi.org/10.1038/s41467-021-21579-5
https://doi.org/10.1038/s41467-021-21579-5
Autor:
Craig T. Parker, Michael E. Konkel, Prabhat K. Talukdar, Colby M Corneau, Christopher R. Gourley, Steven Huynh, Joshua N. Adkins, Geremy Clair, Nicholas M. Negretti
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Frontiers in Microbiology
Frontiers in Microbiology
Major foodborne bacterial pathogens, such as Campylobacter jejuni, have devised complex strategies to establish and foster intestinal infections. For more than two decades, researchers have used immortalized cell lines derived from human intestinal t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e405b934d8cd7b385d3f41c2c9982f2c
https://doi.org/10.3389/fmicb.2019.00755
https://doi.org/10.3389/fmicb.2019.00755
Publikováno v:
Human Emerging and Re-emerging Infections
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4eea9a010d1ad3fa0ca90e2380cb7342
https://doi.org/10.1002/9781118644843.ch28
https://doi.org/10.1002/9781118644843.ch28
Autor:
Christopher R. Gourley, Joshua N. Adkins, Nicholas M. Negretti, Michael E. Konkel, Geremy Clair
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Bile plays an important role in digestion, absorption of fats, and the excretion of waste products, while concurrently providing a critical barrier against colonization by harmful bacteria. Previous studies have demonstrated that gut pathogens react
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e9d17b61a4b6b1d12ac1bfac30a7976
http://europepmc.org/articles/PMC5684402
http://europepmc.org/articles/PMC5684402
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports
Scientific Reports
Accurate repair of DNA damage is crucial to ensure genome stability and cell survival of all organisms. Bile functions as a defensive barrier against intestinal colonization by pathogenic microbes. Campylobacter jejuni, a leading bacterial cause of f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b604280771bf2d18f65ddcd5b732ebf
https://doi.org/10.1038/s41598-017-14646-9
https://doi.org/10.1038/s41598-017-14646-9
Publikováno v:
Trends in Microbiology. 17:371-377
Brucella is an important zoonotic pathogen for which no human vaccine exists. In an infected host, Brucella resides in macrophages but must coordinate expression of multiple virulence factors for successful cell entry and trafficking to acquire this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d15784fb4f0518e64be25d7d80170b2
https://doi.org/10.1016/j.tim.2009.05.006
https://doi.org/10.1016/j.tim.2009.05.006
Autor:
James E. Bruce, Michael E. Konkel, Derrick R. Samuelson, Jason L. O’Loughlin, Jason M. Neal-McKinney, Tyson P. Eucker, Juan D. Chavez, Christopher R. Gourley
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0118533 (2015)
PLoS ONE
PLoS ONE
Campylobacter jejuni is a leading bacterial cause of human gastroenteritis. The goal of this study was to analyze the C. jejuni F38011 strain, recovered from an individual with severe enteritis, at a genomic and proteomic level to gain insight into m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bcccd91b27cfc1760d7e2e010ff1574
http://europepmc.org/articles/PMC4335053?pdf=render
http://europepmc.org/articles/PMC4335053?pdf=render
Publikováno v:
Pathogens and disease. 73(2)
Brucella species utilize diverse virulence factors. Previously, Brucella abortus light-sensing histidine kinase was identified as important for cellular infection. Here, we demonstrate that a Brucella melitensis LOV-HK (BM-LOV-HK) mutant strain has s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45d423deeafdf13427ef07658d44bc6a
https://pubmed.ncbi.nlm.nih.gov/25132657
https://pubmed.ncbi.nlm.nih.gov/25132657