Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Christopher R. Clouser"'
Autor:
Michael O. Ports, Ruth A. Salmon, Blythe Sather, Heidi K. Jessup, Christopher R. Clouser, Lindsey Wimberly, Yue Jiang, Ronald J. Hause, David Kugler, Timothy G. Johnstone, Patrick Carlson, Wendy Curtis, Jon C. Jones, Alex Baturevych, Catherine Sierra, Collin Hauskins, Neha Soni, Melissa Works
Supplementary Figure 1 shows information about the differential effects of lenalidomide with additional scfvs and the selected scfv at an additional E:T ratio with OPM-2 and RPMI-8226 cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66d0afc0464e3243fd418c73786778cf
https://doi.org/10.1158/1535-7163.22506366
https://doi.org/10.1158/1535-7163.22506366
Autor:
Michael O. Ports, Ruth A. Salmon, Blythe Sather, Heidi K. Jessup, Christopher R. Clouser, Lindsey Wimberly, Yue Jiang, Ronald J. Hause, David Kugler, Timothy G. Johnstone, Patrick Carlson, Wendy Curtis, Jon C. Jones, Alex Baturevych, Catherine Sierra, Collin Hauskins, Neha Soni, Melissa Works
Anti–B-cell maturation antigen (BCMA) chimeric antigen receptor (CAR) T cells have shown promising clinical responses in patients with relapsed/refractory multiple myeloma. Lenalidomide, an immunomodulatory drug, potentiates T cell functionality, d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec1de428704b5d6bdfb9b182aec9e142
https://doi.org/10.1158/1535-7163.c.6538380.v1
https://doi.org/10.1158/1535-7163.c.6538380.v1
Autor:
Michael O. Ports, Ruth A. Salmon, Blythe Sather, Heidi K. Jessup, Christopher R. Clouser, Lindsey Wimberly, Yue Jiang, Ronald J. Hause, David Kugler, Timothy G. Johnstone, Patrick Carlson, Wendy Curtis, Jon C. Jones, Alex Baturevych, Catherine Sierra, Collin Hauskins, Neha Soni, Melissa Works
anti-BCMA CAR T amino acid sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b406a8728513acff0fe733a8adcb7e7
https://doi.org/10.1158/1535-7163.22506351.v1
https://doi.org/10.1158/1535-7163.22506351.v1
Autor:
Michael O. Ports, Ruth A. Salmon, Blythe Sather, Heidi K. Jessup, Christopher R. Clouser, Lindsey Wimberly, Yue Jiang, Ronald J. Hause, David Kugler, Timothy G. Johnstone, Patrick Carlson, Wendy Curtis, Jon C. Jones, Alex Baturevych, Catherine Sierra, Collin Hauskins, Neha Soni, Melissa Works
Supplementary Figure 4 shows the effects of lenalidomide on CD27, CCR7, CD45RA, and CAR positivity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1925681cdee8d90e38f67e48891705e4
https://doi.org/10.1158/1535-7163.22506357.v1
https://doi.org/10.1158/1535-7163.22506357.v1
Autor:
Michael O. Ports, Ruth A. Salmon, Blythe Sather, Heidi K. Jessup, Christopher R. Clouser, Lindsey Wimberly, Yue Jiang, Ronald J. Hause, David Kugler, Timothy G. Johnstone, Patrick Carlson, Wendy Curtis, Jon C. Jones, Alex Baturevych, Catherine Sierra, Collin Hauskins, Neha Soni, Melissa Works
Supplementary Figure 2 shows the effect of lenalidomide on BCMA expression of the cell lines used in the experiments in this manuscript.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03c42d08c0f6db0e0ef235edfd100324
https://doi.org/10.1158/1535-7163.22506363.v1
https://doi.org/10.1158/1535-7163.22506363.v1
Autor:
Michael O. Ports, Ruth A. Salmon, Blythe Sather, Heidi K. Jessup, Christopher R. Clouser, Lindsey Wimberly, Yue Jiang, Ronald J. Hause, David Kugler, Timothy G. Johnstone, Patrick Carlson, Wendy Curtis, Jon C. Jones, Alex Baturevych, Catherine Sierra, Collin Hauskins, Neha Soni, Melissa Works
Supplementary Figure 3 shows the effect of lenalidomide on cytokine production by anti-BCMA CAR T cells stimulated with BCMA beads for 24 hours.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e7b4172afe6d412aa4e8eaacba36b43
https://doi.org/10.1158/1535-7163.22506360.v1
https://doi.org/10.1158/1535-7163.22506360.v1
Autor:
Michael O. Ports, Ruth A. Salmon, Blythe Sather, Heidi K. Jessup, Christopher R. Clouser, Lindsey Wimberly, Yue Jiang, Ronald J. Hause, David Kugler, Timothy G. Johnstone, Patrick Carlson, Wendy Curtis, Jon C. Jones, Alex Baturevych, Catherine Sierra, Collin Hauskins, Neha Soni, Melissa Works
Supplementary Methods and Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ed1b249766c63e611f54d59f8c8051
https://doi.org/10.1158/1535-7163.22506354.v1
https://doi.org/10.1158/1535-7163.22506354.v1
Autor:
Michael Ports, Jon C. Jones, Timothy G. Johnstone, Jim Qin, Seamus P. Ragan, Ruth Salmon, Ronald J. Hause, Alex Baturevych, Cecile M. Krejsa, Christopher R. Clouser, Rafael Angel Ponce
Publikováno v:
Journal of Immunotherapy (Hagerstown, Md. : 1997)
Supplemental Digital Content is available in the text.
Chimeric antigen receptor (CAR) T-cell therapy is a promising treatment for patients with CD19+ B-cell malignancies. Combination strategies that improve CAR T-cell potency, limit tumor envir
Chimeric antigen receptor (CAR) T-cell therapy is a promising treatment for patients with CD19+ B-cell malignancies. Combination strategies that improve CAR T-cell potency, limit tumor envir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47988262cbbdd3e4f3972b57fc6a833b
http://europepmc.org/articles/PMC7144752
http://europepmc.org/articles/PMC7144752
Autor:
Bianca Weißbrich, Georg Dössinger, Simon Grassmann, Philipp Lückemeier, Dirk H. Busch, Michael Neuenhahn, Patrick Hoffmann, Sebastian Jarosch, Justin Leube, Kilian Schober, Ludger Klein, Jennifer D. Oduro, Lorenzo Fanchi, Aditya Radhakrishnan, Joel Eggert, Veit R. Buchholz, Florian Voit, Luka Cicin-Sain, Lisa Borkner, Lorenz Mihatsch, Christopher R. Clouser, Enzo Nio, T. Müller
Publikováno v:
Nature immunology. 21(4)
Adaptive evolution is a key feature of T cell immunity. During acute immune responses, T cells harboring high-affinity T cell antigen receptors (TCRs) are preferentially expanded, but whether affinity maturation by clonal selection continues through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b3fb4f4e1359abf78d13c29aaa1fc81
https://pubmed.ncbi.nlm.nih.gov/32205884
https://pubmed.ncbi.nlm.nih.gov/32205884
Autor:
Alex Baturevych, Yue Jiang, Michael Ports, Patrick Carlson, Heidi K. Jessup, David G. Kugler, Neha Soni, Ronald J. Hause, Catherine Sierra, Christopher R. Clouser, Collin Hauskins, Jon C. Jones, Timothy G. Johnstone, Lindsey Wimberly, Melissa Works, Ruth Salmon, Wendy Curtis, Blythe D. Sather
Publikováno v:
Molecular cancer therapeutics. 18(12)
Anti–B-cell maturation antigen (BCMA) chimeric antigen receptor (CAR) T cells have shown promising clinical responses in patients with relapsed/refractory multiple myeloma. Lenalidomide, an immunomodulatory drug, potentiates T cell functionality, d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9caecea46418a9d2776b32c8698555d3
https://pubmed.ncbi.nlm.nih.gov/31395689
https://pubmed.ncbi.nlm.nih.gov/31395689