Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Christopher R Schmidt"'
Autor:
Christoph Plass, Thorsten Zenz, John C. Byrd, Stephan Stilgenbauer, Hartmut Döhner, Peter Lichter, Daniel Mertens, Thomas J. Kipps, Laura Rassenti, Christopher R. Schmidt, Olga Bogatyrova, David Brocks, Matthias Bieg, Manuela Zucknick, Jennifer Hüllein, Yassen Assenov, Lei Gu, Rainer Claus, Christopher C. Oakes
XLSX file 47K, Supplementary table 1: Clinical and biological features of all samples and timepoints used in the study including all genetic alterations found per sample
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::508ce1f0884cea31471d7bc1c4d3d9cc
https://doi.org/10.1158/2159-8290.22530033.v1
https://doi.org/10.1158/2159-8290.22530033.v1
Autor:
Christoph Plass, Thorsten Zenz, John C. Byrd, Stephan Stilgenbauer, Hartmut Döhner, Peter Lichter, Daniel Mertens, Thomas J. Kipps, Laura Rassenti, Christopher R. Schmidt, Olga Bogatyrova, David Brocks, Matthias Bieg, Manuela Zucknick, Jennifer Hüllein, Yassen Assenov, Lei Gu, Rainer Claus, Christopher C. Oakes
XLSX file 15K, Supplementary table 2: Primer sequences used for targeted bisulfite-sequencing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53d90973ebf8445075d122508642fbea
https://doi.org/10.1158/2159-8290.22530030.v1
https://doi.org/10.1158/2159-8290.22530030.v1
Autor:
Christoph Plass, Thorsten Zenz, John C. Byrd, Stephan Stilgenbauer, Hartmut Döhner, Peter Lichter, Daniel Mertens, Thomas J. Kipps, Laura Rassenti, Christopher R. Schmidt, Olga Bogatyrova, David Brocks, Matthias Bieg, Manuela Zucknick, Jennifer Hüllein, Yassen Assenov, Lei Gu, Rainer Claus, Christopher C. Oakes
PDF file 1498K, Supplemental figures 1-10: Methylation analysis of CLL and healthy donor samples using 450k arrays, WGBS and targeted BS-seq, including technical evaluations of the methods used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a44bcce678c83aecf1cbcf1807266c58
https://doi.org/10.1158/2159-8290.22530036.v1
https://doi.org/10.1158/2159-8290.22530036.v1
Autor:
Christopher R. Schmidt
Publikováno v:
Problems of Management in the 21st Century, Vol 11, Iss 1, Pp 43-56 (2016)
State level mechanisms for soliciting, validating, and learning from whistleblower claims of fraud, theft, or misconduct against public colleges and universities are explored in four US states: California, Massachusetts, Michigan, and Ohio. Sequentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc54ae1b61cc28daf9cc1a52ae8ed046
https://doi.org/10.33225/pmc/16.11.43
https://doi.org/10.33225/pmc/16.11.43
Autor:
Christopher R. Schmidt
Publikováno v:
Problems of Management in the 21st Century, Vol 10, Iss 2, Pp 110-120 (2015)
The types of whistleblowing claims made against institutions of higher education are not well understood nor are the various mechanisms used to solicit, investigate, and learn from such claims at the institutional and state levels. This research obta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4972849db1817975ed7a70c8af70b20
https://doi.org/10.33225/pmc/15.10.110
https://doi.org/10.33225/pmc/15.10.110
Autor:
Christopher R. Schmidt, Florian Haller, Joo Hyun Park, Christoph Plass, Jong Bae Park, Yeongran Yoo, Anders Lindroth, Yeon Kyu Lee, Annika Baude, Josef Zustin, Hyun Guy Kang, Irene Krücken, Jörg Fellenberg, Jinyeong Lim, Yoon Jung Park
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
While transcription as regulated by histones and their post-translational modifications has been well described, the function of histone variants in this process remains poorly characterized. Potentially important insight into this process pertain to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df564fe5612dc7b24bdadfbf7ff4c529
https://doi.org/10.1038/s41598-017-13887-y
https://doi.org/10.1038/s41598-017-13887-y
Autor:
Dieter Weichenhan, Daofeng Li, Benedikt Brors, Nakul M. Shah, Christopher R. Schmidt, Simon Haas, Marieke A.G. Essers, Yassen Assenov, Monika Helf, Jing Li, Ting Wang, Olaf Witt, Daniel B. Lipka, Holger Bierhoff, Saiful Islam, Clarissa Gerhäuser, Rainer Will, Johanna Schott, David Brocks, Christopher C. Oakes, Anders Lindroth, Michael Lübbert, Yiran Hou, Ina Oehme, Jan-Philipp Mallm, Georg Stoecklin, Bo Zhang, Karsten Rippe, Michael Daskalakis, Alzbeta Ressnerova, Christoph Plass, Hyo Sik Jang, Sara Laudato, Charles D. Imbusch
Several mechanisms of action have been proposed for DNA methyltransferase and histone deacetylase inhibitors (DNMTi and HDACi), primarily based on candidate-gene approaches. However, less is known about their genome-wide transcriptional and epigenomi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81fac4881bbca39054f4058d021f81ad
https://europepmc.org/articles/PMC6005702/
https://europepmc.org/articles/PMC6005702/
Autor:
Marcus Renner, Carolin Konermann, Lea Geiselhart, Lei Gu, Dieter Weichenhan, Peter Schirmacher, Natalia Becker, Benjamin Goeppert, Arne Warth, Christina Ernst, Olga Bogatyrova, Christoph Plass, Frederick Klauschen, Albrecht Stenzinger, M Hafezi, Manuela Zucknick, Kai Breuhahn, Christopher R. Schmidt, Wilko Weichert, Arianeb Mehrabi
Publikováno v:
Hepatology. 59:544-554
The molecular mechanisms underlying the genesis of cholangiocarcinomas (CCs) are poorly understood. Epigenetic changes such as aberrant hypermethylation and subsequent atypical gene expression are characteristic features of most human cancers. In CC,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6aa6cbfc3900231f4aef37719d07d78f
https://doi.org/10.1002/hep.26721
https://doi.org/10.1002/hep.26721
Autor:
David Brocks, Christopher R Schmidt, Michael Daskalakis, Hyo Sik Jang, Nakul M Shah, Daofeng Li, Jing Li, Bo Zhang, Yiran Hou, Sara Laudato, Daniel B Lipka, Johanna Schott, Holger Bierhoff, Yassen Assenov, Monika Helf, Alzbeta Ressnerova, Md Saiful Islam, Anders M Lindroth, Simon Haas, Marieke Essers, Charles D Imbusch, Benedikt Brors, Ina Oehme, Olaf Witt, Michael Lübbert, Jan-Philipp Mallm, Karsten Rippe, Rainer Will, Dieter Weichenhan, Georg Stoecklin, Clarissa Gerhäuser, Christopher C Oakes, Ting Wang, Christoph Plass
Publikováno v:
Nature Genetics. 49:1661-1661
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9041cf903232dfb907d955cd1396dce
https://doi.org/10.1038/ng1117-1661c
https://doi.org/10.1038/ng1117-1661c
Autor:
Manuela Zucknick, Yassen Assenov, Christoph Plass, Rainer Claus, Olga Bogatyrova, Hartmut Döhner, Lei Gu, John C. Byrd, Peter Lichter, Stephan Stilgenbauer, Christopher C. Oakes, Matthias Bieg, Laura Z. Rassenti, Jennifer Hüllein, Thorsten Zenz, David Brocks, Thomas J. Kipps, Christopher R. Schmidt, Daniel Mertens
Publikováno v:
Cancer discovery, vol 4, iss 3
Although clonal selection by genetic driver aberrations in cancer is well documented, the ability of epigenetic alterations to promote tumor evolution is undefined. We used 450k arrays and next-generation sequencing to evaluate intratumor heterogenei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9c94c581d3e3c827af973654f1a7a2a
https://pubmed.ncbi.nlm.nih.gov/24356097
https://pubmed.ncbi.nlm.nih.gov/24356097