Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Christopher R McMaster"'
Autor:
Christopher J. Barden, Fan Wu, J. Pedro Fernandez-Murray, Erhu Lu, Shengguo Sun, Marcia M. Taylor, Annette L. Rushton, Jason Williams, Mahtab Tavasoli, Autumn Meek, Alla Siva Reddy, Lisa M. Doyle, Irina Sagamanova, Kovilpitchai Sivamuthuraman, Robert T. M. Boudreau, David M. Byers, Donald F. Weaver, Christopher R. McMaster
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract The World Health Organization has identified antibiotic resistance as one of the three greatest threats to human health. The need for antibiotics is a pressing matter that requires immediate attention. Here, computer-aided drug design is use
Externí odkaz:
https://doaj.org/article/d68ded4d00cb4c5f9f17aa749d95ef6c
Autor:
J Pedro Fernández-Murray, Sergey V Prykhozhij, J Noelia Dufay, Shelby L Steele, Daniel Gaston, Gheyath K Nasrallah, Andrew J Coombs, Robert S Liwski, Conrad V Fernandez, Jason N Berman, Christopher R McMaster
Publikováno v:
PLoS Genetics, Vol 12, Iss 1, p e1005783 (2016)
Sideroblastic anemias are acquired or inherited anemias that result in a decreased ability to synthesize hemoglobin in red blood cells and result in the presence of iron deposits in the mitochondria of red blood cell precursors. A common subtype of c
Externí odkaz:
https://doaj.org/article/8a4c7a287d044ee8b2967e4581066e2d
Autor:
Michael H Ngo, Joanna Borowska-Fielding, Godfrey Heathcote, Sara Nejat, Melanie E Kelly, Christopher R McMaster, Johane M Robitaille
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0158320 (2016)
Mutations in genes that code for components of the Norrin-FZD4 ligand-receptor complex cause the inherited childhood blinding disorder familial exudative vitreoretinopathy (FEVR). Statistical evidence from studies of patients at risk for the acquired
Externí odkaz:
https://doaj.org/article/2c02dad2af0b47a1b2910246e0a0dc0e
Autor:
Daniel Gaston, Samantha Hansford, Carla Oliveira, Mathew Nightingale, Hugo Pinheiro, Christine Macgillivray, Pardeep Kaurah, Andrea L Rideout, Patricia Steele, Gabriela Soares, Weei-Yuarn Huang, Scott Whitehouse, Sarah Blowers, Marissa A LeBlanc, Haiyan Jiang, Wenda Greer, Mark E Samuels, Andrew Orr, Conrad V Fernandez, Jacek Majewski, Mark Ludman, Sarah Dyack, Lynette S Penney, Christopher R McMaster, David Huntsman, Karen Bedard
Publikováno v:
PLoS Genetics, Vol 10, Iss 10, p e1004669 (2014)
Gastric cancer is among the leading causes of cancer-related deaths worldwide. While heritable forms of gastric cancer are relatively rare, identifying the genes responsible for such cases can inform diagnosis and treatment for both hereditary and sp
Externí odkaz:
https://doaj.org/article/218c6627cf0742139b00ee32b9763ae2
Autor:
Liam D. Redden, Douglas S.M. Iaboni, Sarah van der Ende, Mathew Nightingale, Daniel Gaston, Christopher R. McMaster, Johane M. Robitaille, R. Rishi Gupta
Publikováno v:
American Journal of Ophthalmology Case Reports, Vol 34, Iss , Pp 102051- (2024)
Purpose: To report a rare clinical finding of preretinal granules associated with atypical familial exudative vitreoretinopathy (FEVR) and perform a review of the literature. Observations: An asymptomatic 18-year-old male was referred for unilateral
Externí odkaz:
https://doaj.org/article/f431d01d49954f5086b1f69028654a4a
Autor:
Marissa A LeBlanc, Gregory D Fairn, Sarah B Russo, Ola Czyz, Vanina Zaremberg, L Ashley Cowart, Christopher R McMaster
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60485 (2013)
The oxysterol binding protein family are amphitropic proteins that bind oxysterols, sterols, and possibly phosphoinositides, in a conserved binding pocket. The Saccharomyces cerevisiae oxysterol binding protein family member Kes1 (also known as Osh4)
Externí odkaz:
https://doaj.org/article/f55bddbbe31541aca1f7adcaee85a951
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e55388 (2013)
The Sec14 protein domain is a conserved tertiary structure that binds hydrophobic ligands. The Sec14 protein from Saccharomyces cerevisiae is essential with studies of S. cerevisiae Sec14 cellular function facilitated by a sole temperature sensitive
Externí odkaz:
https://doaj.org/article/a3cc255ebcd948818cf91b34c3ed5e17
Autor:
Abhishek Mishra, Mahtab Tavasoli, Stanislav Sokolenko, Christopher R. McMaster, Kishore B.S. Pasumarthi
Publikováno v:
iScience, Vol 27, Iss 1, Pp 108748- (2024)
Summary: It has been shown that atrial natriuretic peptide (ANP) and its high affinity receptor (NPRA) are involved in the formation of ventricular conduction system (VCS). Inherited genetic variants in fatty acid oxidation (FAO) genes are known to c
Externí odkaz:
https://doaj.org/article/2965de36686d4d4da3c2a89e3625fde5
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 8, Pp 100213- (2022)
Externí odkaz:
https://doaj.org/article/b9b4115644d042e48c4c9ee5abfdfe34
Autor:
Carla S. D'Angelo, Azure Hermes, Christopher R. McMaster, Elissa Prichep, Étienne Richer, Francois H. van der Westhuizen, Gabriela M. Repetto, Gong Mengchun, Helen Malherbe, Juergen K. V. Reichardt, Laura Arbour, Maui Hudson, Kelly du Plessis, Melissa Haendel, Phillip Wilcox, Sally Ann Lynch, Shamir Rind, Simon Easteal, Xavier Estivill, Yarlalu Thomas, Gareth Baynam
Publikováno v:
Frontiers in Pediatrics, Vol 8 (2020)
Advances in omics and specifically genomic technologies are increasingly transforming rare disease diagnosis. However, the benefits of these advances are disproportionately experienced within and between populations, with Indigenous populations frequ
Externí odkaz:
https://doaj.org/article/fd0e65b495e942c6b66615fabcd72740