Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Christopher R Jenkins"'
Autor:
Connie J. Eaves, Hongfang Wang, Jon C. Aster, Oksana Nemirovsky, R. Keith Humphries, Andrew P. Weng, Christopher R Jenkins, Carol Wai, Sonya H Lam, Sam Gusscott, Mark Y. Chiang, Olena O Shevchuk, Vincenzo Giambra
Publikováno v:
Nature Medicine. 18:1693-1698
Reactive oxygen species (ROS), a byproduct of cellular metabolism, damage intracellular macromolecules and, when present in excess, can promote normal hematopoietic stem cell differentiation and exhaustion. However, mechanisms that regulate the amoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fda44a27f4c7f84388732e2bf0ce37e0
https://doi.org/10.1038/nm.2960
https://doi.org/10.1038/nm.2960
Autor:
Marco M. Gottardis, Christopher R Jenkins, Olena O Shevchuk, Andrew P. Weng, Michael Pollak, Vincenzo Giambra, Martin Holzenberger, Sonya H Lam, Joan M. Carboni, R. Keith Humphries
Publikováno v:
Experimental hematology. 40(9)
Malignanttransformationofnormalhematopoieticprogenitorsisamultistepprocessthatlikely requires interaction between collaborating oncogenic signals at critical junctures. For instance, the MLL-AF9 fusion oncogene is thought to contribute to myeloid leu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1f92edfda7a030a3a5722bba35af4aa
https://pubmed.ncbi.nlm.nih.gov/22613471
https://pubmed.ncbi.nlm.nih.gov/22613471
Autor:
Christopher R Jenkins, Bruce Woolcock, Joseph M. Connors, Andrew P. Weng, Chris Cochrane, Merrill Boyle, Marco A. Marra, Christian Steidl, Randy D. Gascoyne, Susana Ben-Neriah, Robert Kridel, Barbara Meissner, Adele Telenius, Sanja Rogic, Stephen Opat, Jay Gunawardana, Laurie H. Sehn, Ryan D. Morin, King Tan
Publikováno v:
Blood. 119(9)
Mantle cell lymphoma (MCL), an aggressive subtype of non-Hodgkin lymphoma, is characterized by the hallmark translocation t(11;14)(q13;q32) and the resulting overexpression of cyclin D1 (CCND1). Our current knowledge of this disease encompasses frequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01a5567703bfd69014180c838b448ecb
https://pubmed.ncbi.nlm.nih.gov/22383787
https://pubmed.ncbi.nlm.nih.gov/22383787
Publikováno v:
Stem Cells and Human Diseases ISBN: 9789400728004
In the last few years, the concepts governing our understanding of cancer have changed. In particular, the point of view that many leukemias are developmentally well-defined and, like in normal hematopoiesis, driven by a relatively small subset of ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32d499740d60732ca2d15d33a5f56326
https://doi.org/10.1007/978-94-007-2801-1_13
https://doi.org/10.1007/978-94-007-2801-1_13
Autor:
Susan Buchanan, Christopher R. Jenkins
Publikováno v:
Australian dental journal. 42(4)
A case of natal teeth associated with traumatic ulceration to the ventral surface of the tongue (Riga-Fedes syndrome) in a four week old boy is presented. On radiographic examination, two teeth, present at birth, were found to be early erupted decidu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ed97d8a46baa581a817a002290d0dbd
https://pubmed.ncbi.nlm.nih.gov/9316308
https://pubmed.ncbi.nlm.nih.gov/9316308
Autor:
Sonya Lam, Vincenzo Giambra, R. Keith Humphries, Carol Wai, Oksana Nemirovsky, Andrew P. Weng, Connie J. Eaves, Christopher R Jenkins, Hind Medyouf
Publikováno v:
Blood. 116:12-12
Abstract 12 T-cell acute lymphoblastic leukemia (T-ALL) is a malignancy of immature T cell progenitors which affects both children and adults. Current therapies achieve cure in about 80% of pediatric patients, but only 40% of adults survive beyond 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbf8d7f0f44b81e3109548962684b87d
https://doi.org/10.1182/blood.v116.21.12.12
https://doi.org/10.1182/blood.v116.21.12.12