Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Christopher R Helps"'
Autor:
Francesca Genova, Simona Nonnis, Elisa Maffioli, Gabriella Tedeschi, Maria Giuseppina Strillacci, Michela Carisetti, Giuseppe Sironi, Francesca Anna Cupaioli, Noemi Di Nanni, Alessandra Mezzelani, Ettore Mosca, Christopher R. Helps, Peter A. J. Leegwater, Laetitia Dorso, Lives Consortium, Maria Longeri
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract The amyloidoses constitute a group of diseases occurring in humans and animals that are characterized by abnormal deposits of aggregated proteins in organs, affecting their structure and function. In the Abyssinian cat breed, a familial form
Externí odkaz:
https://doaj.org/article/7f545cc278954ca080efd477d079a003
Autor:
Alana R. Rodney, Reuben M. Buckley, Robert S. Fulton, Catrina Fronick, Todd Richmond, Christopher R. Helps, Peter Pantke, Dianne J. Trent, Karen M. Vernau, John S. Munday, Andrew C. Lewin, Rondo Middleton, Leslie A. Lyons, Wesley C. Warren
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Over 94 million domestic cats are susceptible to cancers and other common and rare diseases. Whole exome sequencing (WES) is a proven strategy to study these disease-causing variants. Presented is a 35.7 Mb exome capture design based on the
Externí odkaz:
https://doaj.org/article/e18ff08359a64385b50b033630e617e2
Autor:
Emi N. Barker, Philippa Lait, Lorenzo Ressel, Emily-Jayne Blackwell, Séverine Tasker, Helen Kedward-Dixon, Anja Kipar, Christopher R. Helps
Publikováno v:
Pathogens, Vol 9, Iss 7, p 535 (2020)
Feline infectious peritonitis (FIP) is a common infectious cause of death in cats, with heritable host factors associated with altered risk of disease. To assess the role of feline interferon-gamma gene (fIFNG) variants in this risk, the allele frequ
Externí odkaz:
https://doaj.org/article/f2b82b1b6cae46d79c939ac158e25227
Autor:
Kate James, Séverine Tasker, Sophie Keyte, Richard Wall, Swaid Abdullah, Hannah Newbury, Christopher R Helps
Publikováno v:
Keyte, S, Abdullah, S, James, K, Newbury, H, Helps, C, Tasker, S & Wall, R 2021, ' Prevalence and distribution of Anaplasma phagocytophilum in ticks collected from dogs in the United Kingdom ', Veterinary Record, vol. 188, no. 8, e12, pp. 1-7 . https://doi.org/10.1002/vetr.12
BACKGROUND: Anaplasma phagocytophilum is the etiological agent of canine granulocytic anaplasmosis in dogs and causes human granulocytic anaplasmosis (HGA). Tick-borne anaplasmosis has been recognised as an emerging zoonotic health concern worldwide.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8dccfcc9bd98ff2726a8fa6aad3f40
https://research-information.bris.ac.uk/en/publications/00b89027-f9f4-4374-9db1-f678b89e0664
https://research-information.bris.ac.uk/en/publications/00b89027-f9f4-4374-9db1-f678b89e0664
Autor:
Catrina Fronick, Todd Richmond, Dianne J. Trent, John S. Munday, Alana R. Rodney, Robert S. Fulton, Christopher R Helps, Andrew C. Lewin, Leslie A. Lyons, Karen M. Vernau, Rondo P. Middleton, Reuben M. Buckley, Wesley C. Warren, Peter Pantke
Publikováno v:
Scientific reports, vol 11, iss 1
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports
Over 94 million domestic cats are susceptible to cancers and other common and rare diseases. Whole exome sequencing (WES) is a proven strategy to study these disease-causing variants. Presented is a 35.7 Mb exome capture design based on the annotated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f88c385059d3e7b8eb74ffd58e9a405
https://escholarship.org/uc/item/3dk0k7tr
https://escholarship.org/uc/item/3dk0k7tr
Publikováno v:
BSAVA Congress 2021: Clinical abstract presentations ISBN: 9781913859039
BSAVA Congress Proceedings 2020 ISBN: 9781910443767
BSAVA Congress Proceedings 2020 ISBN: 9781910443767
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::890f62cf4de882cbc0a56b13f4d869aa
https://doi.org/10.22233/9781913859039.14
https://doi.org/10.22233/9781913859039.14
Autor:
Julia H. Wildschutte, Marta G. Castelhano, Max F. Rothschild, Maria Kaukonen, Georgios Kellaris, Joshua A. Stern, Stéphane Bézieau, Laurence Legeai-Mallet, Shrinivas P. Mane, Dominique Debray, Hannes Lohi, Ottmar Distl, Laurence M. Occelli, Kinga M. Bujakowska, Marjo K. Hytönen, Oliver P. Forman, Elizabeth A. Wilcox, Richard Malik, Tosso Leeb, Ronald H.L. Li, Elizabeth L. Cadena, William F. Swanson, Teri L. Lear, Yoshihiko Yu, Robert J. Harvey, Dominique Caldari, Erica E. Davis, Bianca Haase, Eric A. Pierce, Reuben M. Buckley, Stephen P. Daiger, L. Martin, D. Aberdein, Clare Rusbridge, Simon M. Petersen-Jones, Edward I. Ginns, Daniel C. Koboldt, Benjamin Cogné, Lokuliyanage Dona Samudita Senaratne, Michael B. Gorin, Niels C Pedersen, Margret L. Casal, Xenia Latypova, Adam R. Boyko, Isabel Hernandez, Tomoki Kosho, Sara J. Bowne, Nicholas H. Dodman, Tomas F. Bergström, Nicholas Katsanis, Rebecca R. Bellone, Guylène Le Meur, Bertrand Isidor, Daisuke Hasegawa, Christopher B. Kaelin, Mathilde Nizon, Karen A. Terio, Paulo C. Alves, Leslie A. Lyons, Christopher R Helps, Eirik Frengen, Emilie Leclerc, William J. Murphy, Beth Shapiro, Mark A. Magnuson, Lorraine Fievet, Maria Longeri, Rory J. Todhunter, Jeffrey A. Brockman, Lori S. Sullivan, Dorian J. Garrick, Jens Häggström, Jonathan E. Fogle, N. Matthew Ellinwood, Wesley C. Warren, John S. Munday, Gregory S. Barsh
Publikováno v:
American Journal of Human Genetics
American Journal of Human Genetics, Elsevier (Cell Press), 2020, 106, pp.893-904. ⟨10.1016/j.ajhg.2020.04.005⟩
Am J Hum Genet
American Journal of Human Genetics, Elsevier (Cell Press), 2020, 106, pp.893-904. ⟨10.1016/j.ajhg.2020.04.005⟩
Am J Hum Genet
Kinesin-2 enables ciliary assembly and maintenance as an anterograde intraflagellar transport (IFT) motor. Molecular motor activity is driven by a heterotrimeric complex comprised of KIF3A and KIF3B or KIF3C plus one non-motor subunit, KIFAP3. Using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a48a8e4787ee74d7e392a0a9500b3f4d
https://hal.archives-ouvertes.fr/hal-03490699
https://hal.archives-ouvertes.fr/hal-03490699
Autor:
Catrina Fronick, Dianne J. Trent, Reuben M. Buckley, Robert S. Fulton, Peter Pantke, Todd Richmond, Leslie A. Lyons, Alana R. Rodney, Christopher R Helps, Wesley C. Warren
Over 94 million domestic cats are considered pets, who, as our companions, are also susceptible to cancers, common and rare diseases. Whole exome sequencing (WES) is a cost-effective strategy to study their putative disease-causing variants. Presente
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::375b3cc67508f2aae60c1f7e688381cc
https://doi.org/10.1101/2020.06.01.128405
https://doi.org/10.1101/2020.06.01.128405
Publikováno v:
Kedward-Dixon, H, Barker, E N, Tasker, S, Kipar, A & Helps, C 2019, ' Evaluation of polymorphisms in inflammatory mediator and cellular adhesion genes as risk factors for feline infectious peritonitis ', Journal of Feline Medicine and Surgery . https://doi.org/10.1177/1098612X19865637
Objectives Feline infectious peritonitis (FIP) is a high mortality infectious disease. Single nucleotide polymorphisms (SNPs) in the genes encoding interferon gamma ( IFNG), tumour necrosis factor alpha ( TNFA) and dendritic cell-specific intercellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdf49669b00b5d5b9de831f3403e335e
https://doi.org/10.5167/uzh-175812
https://doi.org/10.5167/uzh-175812
Publikováno v:
Abdullah, S, Lait, P, Helps, C, Newbury, H & Wall, R 2020, ' The prevalence of Rickettsia felis DNA in fleas collected from cats and dogs in the UK ', Veterinary Parasitology, vol. 282, 109143 . https://doi.org/10.1016/j.vetpar.2020.109143
In a large-scale survey in the UK, recruited veterinary practices were asked to inspect client-owned cats and dogs, selected at random between April and June 2018, following a standardised flea inspection protocol. A total of 326 veterinary practices
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d6e649b291a68111fbb192a9f692b7
https://research-information.bris.ac.uk/en/publications/828b4417-1af1-4ffb-a49a-61b9eedfd0db
https://research-information.bris.ac.uk/en/publications/828b4417-1af1-4ffb-a49a-61b9eedfd0db