Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Christopher R, Paradise"'
Autor:
Ian T. McGraw, MD, Erin Elise Wilson, BS, Atta Behfar, MD, PhD, Christopher R. Paradise, PhD, Rod J. Rohrich, MD, Saranya P. Wyles, MD, PhD
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 12, Iss 8, p e6061 (2024)
Summary:. Exosomes, or extracellular vesicles, represent the latest cell-free addition to the regenerative medicine toolkit. In vitro preclinical studies have demonstrated the safety and efficacy of exosomes, which vary based on source and biomanufac
Externí odkaz:
https://doaj.org/article/43d3dc676d7c4d94bde9c24f72592afa
Autor:
Tyler J. Rolland, Timothy E. Peterson, Ramandeep Takhter, Skylar A. Rizzo, Soulmaz Boroumand, Ao Shi, Tyra A. Witt, Mary Nagel, Cassandra K. Kisby, Sungjo Park, Lois A. Rowe, Christopher R. Paradise, Laura R. E. Becher, Brooke D. Paradise, Paul G. Stalboerger, Emanuel C. Trabuco, Atta Behfar
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-17 (2022)
Abstract Urinary incontinence afflicts up to 40% of adult women in the United States. Stress urinary incontinence (SUI) accounts for approximately one-third of these cases, precipitating ~200,000 surgical procedures annually. Continence is maintained
Externí odkaz:
https://doaj.org/article/f302f092892549b692c321282915b005
Autor:
Amel Dudakovic, Sofia Jerez, Padmini J. Deosthale, Janet M. Denbeigh, Christopher R. Paradise, Martina Gluscevic, Pengfei Zan, Dana L. Begun, Emily T. Camilleri, Oksana Pichurin, Farzaneh Khani, Roman Thaler, Jane B. Lian, Gary S. Stein, Jennifer J. Westendorf, Lilian I. Plotkin, Andre J. van Wijnen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract High-throughput microRNA sequencing was performed during differentiation of MC3T3-E1 osteoblasts to develop working hypotheses for specific microRNAs that control osteogenesis. The expression data show that miR-101a, which targets the mRNAs
Externí odkaz:
https://doaj.org/article/f5c778c9a9e84a5d9acbf3c478897543
Autor:
Christopher R Paradise, Rodolfo E De La Vega, M Lizeth Galvan, Margarita E Carrasco, Roman Thaler, Andre J vanWijnen, Amel Dudakovic
Publikováno v:
JBMR Plus, Vol 5, Iss 10, Pp n/a-n/a (2021)
ABSTRACT Bromodomain (BRD) proteins are histone code interpreters that recognize acetylated lysines and link the dynamic state of chromatin with the transcriptional machinery. Here, we demonstrate that ablation of the Brd4 gene in primary mouse bone
Externí odkaz:
https://doaj.org/article/0f084c9fd5ba4ab08e548ed95f5d960f
Autor:
Tyler J. Rolland, Timothy E. Peterson, Raman Deep Singh, Skylar A. Rizzo, Soulmaz Boroumand, Ao Shi, Tyra A. Witt, Mary Nagel, Cassandra K. Kisby, Sungjo Park, Lois A. Rowe, Christopher R. Paradise, Laura R. E. Becher, Brooke D. Paradise, Paul G. Stalboerger, Emanuel C. Trabuco, Atta Behfar
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/cfa46d27f5aa475783881ef28822d402
Publikováno v:
Advances in Cosmetic Surgery. 6:31-41
Autor:
Sydney L Proffer, Christopher R Paradise, Emily DeGrazia, Yael Halaas, K Kay Durairaj, Michael Somenek, Angela Sivly, Andrea J Boon, Atta Behfar, Saranya P Wyles
Publikováno v:
Aesthetic Surgery Journal. 42:1185-1193
Background Exosomes are regenerative mediators for skin rejuvenation. Human platelet extract (HPE) is an allogeneic exosome product derived from US-sourced, leukocyte-reduced apheresed platelets with consistent purity and potency. Objectives The auth
Autor:
Parisa Dashti, Jeroen van de Peppel, Roman Thaler, Christopher R. Paradise, Gary S. Stein, Martin A. Montecino, Johannes P.T.M. van Leeuwen, Bram J. van der Eerden, Amel Dudakovic, Andre J. van Wijnen
Publikováno v:
Gene, 851:146928. Elsevier
Bone formation is controlled by histone modifying enzymes that regulate post-translational modifications on nucleosomal histone proteins and control accessibility of transcription factors to gene promoters required for osteogenesis. Enhancer of Zeste
Autor:
Dileep D. Monie, Fredric B. Meyer, Richard E. Hayden, Andre Terzic, Christopher R. Paradise, Saranya P. Wyles
Publikováno v:
Regenerative Medicine
The biology of regenerative medicine has steadily matured, providing the foundation for randomized clinical trials and translation into validated applications. Today, the growing regenerative armamentarium is poised to impact disease management, yet
Autor:
Afton K. Limberg, Christopher G. Salib, Andre J. van Wijnen, Eric A. Lewallen, Banu Bayram, Matthew P. Abdel, Daniel J. Berry, William H. Trousdale, Joaquin Sanchez-Sotelo, Mark E. Morrey, Jacob W. Bettencourt, Roman Thaler, Christopher R. Paradise, Nicolas Reina
Publikováno v:
Genomics
Arthrofibrosis is an abnormal histopathologic response, is debilitating for patients, and poses a substantial unsolved clinical challenge. This study characterizes molecular biomarkers and regulatory pathways associated with arthrofibrosis by compari