Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Christopher R, Bolen"'
Autor:
Lale Kostakoglu, Federico Dalmasso, Paola Berchialla, Larry A. Pierce, Umberto Vitolo, Maurizio Martelli, Laurie H. Sehn, Marek Trněný, Tina G. Nielsen, Christopher R. Bolen, Deniz Sahin, Calvin Lee, Tarec Christoffer El‐Galaly, Federico Mattiello, Paul E. Kinahan, Stephane Chauvie
Publikováno v:
eJHaem, Vol 3, Iss 2, Pp 406-414 (2022)
Abstract Image texture analysis (radiomics) uses radiographic images to quantify characteristics that may identify tumour heterogeneity and associated patient outcomes. Using fluoro‐deoxy‐glucose positron emission tomography/computed tomography (
Externí odkaz:
https://doaj.org/article/b8bbe56c53944bd0a888cd8d151c81e5
Autor:
Eugene Kim, Yanwen Jiang, Tao Xu, Alexandra Bazeos, Andrea Knapp, Christopher R. Bolen, Kathryn Humphrey, Tina G. Nielsen, Elicia Penuel, Joseph N. Paulson
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease defined using a number of well-established molecular subsets. Application of non-negative matrix factorization (NMF) to whole exome sequence data has previously been
Externí odkaz:
https://doaj.org/article/9441884b67174e7899c81ec15aa60785
Autor:
Laurie H. Sehn, Maurizio Martelli, Marek Trněný, Wenxin Liu, Christopher R. Bolen, Andrea Knapp, Deniz Sahin, Gila Sellam, Umberto Vitolo
Publikováno v:
Journal of Hematology & Oncology, Vol 13, Iss 1, Pp 1-9 (2020)
Abstract Background Rituximab (R) plus cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) is the current standard therapy for diffuse large B cell lymphoma (DLBCL). Obinutuzumab (G), a glycoengineered, type II anti-CD20 monoclonal anti
Externí odkaz:
https://doaj.org/article/071cf3f888fc49b89a4d025320426315
Autor:
Hussein A. Abbas, Vakul Mohanty, Ruiping Wang, Yuefan Huang, Shaoheng Liang, Feng Wang, Jianhua Zhang, Yihua Qiu, Chenyue W. Hu, Amina A. Qutub, Monique Dail, Christopher R. Bolen, Naval Daver, Marina Konopleva, Andrew Futreal, Ken Chen, Linghua Wang, Steven M. Kornblau
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Acute myeloid leukemia (AML) is a heterogeneous disease with variable responses to therapy. Cytogenetic and genomic features are used to classify AML patients into prognostic and treatment groups. However, these molecular characteristics harbor signi
Externí odkaz:
https://doaj.org/article/3fa0453989f444be9cf6786abeda8ff8
Autor:
Christopher R. Bolen, Ronald McCord, Sarah Huet, Garrett M. Frampton, Richard Bourgon, Fabrice Jardin, Peggy Dartigues, Elizabeth A. Punnoose, Edith Szafer-Glusman, Luc Xerri, Pierre Sujobert, Gilles Salles, Jeffrey M. Venstrom
Publikováno v:
Blood Advances, Vol 1, Iss 22, Pp 1884-1890 (2017)
Abstract: Identifying follicular lymphoma (FL) patients with preexisting antitumor immunity will inform precision medicine strategies for novel cancer immunotherapies. Using clinical and genomic data from 249 FL patients, we determined the clinical i
Externí odkaz:
https://doaj.org/article/077c0f2c08d74e3c89a954500baaa162
Autor:
Christopher R. Bolen, Magdalena Klanova, Marek Trneny, Laurie H. Sehn, Jie He, Jing Tong, Joseph N. Paulson, Eugene Kim, Umberto Vitolo, Alice Di Rocco, Günter Fingerle-Rowson, Tina Nielsen, Georg Lenz, Mikkel Z. Oestergaard
Publikováno v:
Haematologica, Vol 105, Iss 9 (2019)
Diffuse large B-cell lymphoma represents a biologically and clinically heterogeneous diagnostic category with well-defined cell-of-origin subtypes. Using data from the GOYA study (NCT01287741), we characterized the mutational profile of diffuse large
Externí odkaz:
https://doaj.org/article/777088f6dae24217ab48122ac29d0dd2
Increased T Cell Differentiation and Cytolytic Function in Bangladeshi Compared to American Children
Autor:
Lisa E. Wagar, Christopher R. Bolen, Natalia Sigal, Cesar J. Lopez Angel, Leying Guan, Beth D. Kirkpatrick, Rashidul Haque, Robert J. Tibshirani, Julie Parsonnet, William A. Petri, Mark M. Davis
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
During the first 5 years of life, children are especially vulnerable to infection-related morbidity and mortality. Conversely, the Hygiene Hypothesis suggests that a lack of exposure to infectious agents early in life could explain the increasing inc
Externí odkaz:
https://doaj.org/article/7eda52eb9d10465cbf66c63ae683fec5
Autor:
Shadi Toghi Eshghi, Amelia Au-Yeung, Chikara Takahashi, Christopher R. Bolen, Maclean N. Nyachienga, Sean P. Lear, Cherie Green, W. Rodney Mathews, William E. O'Gorman
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Dimensionality reduction using the t-Distributed Stochastic Neighbor Embedding (t-SNE) algorithm has emerged as a popular tool for visualizing high-parameter single-cell data. While this approach has obvious potential for data visualization it remain
Externí odkaz:
https://doaj.org/article/8d2df7532958427ba25ff952ae0e2d72
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 4, p e1006899 (2019)
Small sample sizes combined with high person-to-person variability can make it difficult to detect significant gene expression changes from transcriptional profiling studies. Subtle, but coordinated, gene expression changes may be detected using gene
Externí odkaz:
https://doaj.org/article/69bbfd50bb0c4462ae1130ade74fd442
Autor:
Camille Laurent, Maria Flores, Loïc Chartier, Sarah Huet, Christopher R. Bolen, Jeffrey M. Venstrom, Catherine Chassagne‐Clément, Peggy Dartigues‐Cuilléres, Fréderic Charlotte, Bruno Tesson, Gilles Salles, Franck Morschhauser, Luc Xerri
Publikováno v:
British Journal of Haematology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::652ac69aeb9aa6f55324085cdd3b9490
https://doi.org/10.1111/bjh.18881
https://doi.org/10.1111/bjh.18881