Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Christopher Piercy"'
Publikováno v:
Springer Seminars in Immunopathology. 18:51-56
Autoreactive T cells are part of the normal lymphocyte repertoire of healthy individuals [4]. In the immune system of healthy individuals, potent regulatory mechanisms control T and B cell tolerance to self antigens. While genetic factors influence s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bba8b43176a1b4a72e52762aa0931c98
https://doi.org/10.1007/bf00792608
https://doi.org/10.1007/bf00792608
Autor:
C. Garrison Fathman, Lawrence Steinman, Anand M. Gautam, Koenraad Gijbels, Stefan Brocke, Amitabh Gaur, Christopher Piercy
Publikováno v:
Nature. 365:642-644
THE role of infection in the pathogenesis of clinical relapses that occur in most autoimmune diseases, including multiple sclerosis, remains to be established1,2. Experimental autoimmune encephalomyelitis (EAE) serves as a model for multiple sclerosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cfc1d60950c42dbc8a30ba5cf13ab96
https://doi.org/10.1038/365642a0
https://doi.org/10.1038/365642a0
Autor:
Amy J. Perou, Kelly Sheppard, Eva Bajorek, Nu T. Vo, Michael Olivier, Amita Aggarwal, Tonya J. Jeffrey, Joseph P. Marquis, Wei-Lin Sun, Xia Liu, Tisha R. Chung, Saskia C. Lewis, Valerie I. Bustos, Nguyet M. Tran, Ellen M. Beasley, Ravi Sachidanandam, Barbara J. Trask, Angela Chu, Robert W. Freudenberg, Robert A. Martinez, Nedda S. Misherghi, Mirian Denys, Margaret K. Matsuura, Frederick Lopez, David Hadley, Tim Reif, Michelle R. Levy, Shaying Zhao, Brent Louie, Fawn Qin, Richard M. Myers, Vida Shokoohi, Tejeda, Annalisa A. Almendras, Jannette M. Bushard, Elizabeth A. Stewart, J. Fernando, Nicole Y. Fang, Libby R. Hamilton, Deborah L. Zierten, Tonatiuh Trejo, Laura C. Lazzeroni, Christopher Piercy, Adam B. Olshen, Shanti M. Perkins, Mark Piercy, Shannon D. Brady, David R. Cox, Geoff A. Smick, Brian D. Foster, Rakly Dominguez, Jolanna A. Norton, Simon C. M. Yan, Jennifer Allen, Libusha Kelly, Anniek de Witte
Publikováno v:
Science (New York, N.Y.). 291(5507)
We have constructed a physical map of the human genome by using a panel of 90 whole-genome radiation hybrids (the TNG panel) in conjunction with 40,322 sequence-tagged sites (STSs) derived from random genomic sequences as well as expressed sequences.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7db1cc212b9e6c44559377b04860881d
https://pubmed.ncbi.nlm.nih.gov/11181994
https://pubmed.ncbi.nlm.nih.gov/11181994
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 96(12)
The role of various adhesion molecules in lymphocyte homing to the brain and in inflammatory autoimmune disease of the central nervous system (CNS) was examined in mice. Activated T cell lines and clones expressed CD44 and integrin α4, but not L-sel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69d3bbff417b9707db1b03865fe7b181
https://pubmed.ncbi.nlm.nih.gov/10359810
https://pubmed.ncbi.nlm.nih.gov/10359810
Autor:
David C. Wraith, Lawrence Steinman, Timo Veromaa, C G Fathman, Paul J. Fairchild, I. Ferber, Anne O'Garra, Ursula Utz, Paul J. Conlon, Koenraad Gijbels, Stefan Brocke, Nathan Karin, Dennis J. Mitchell, Ari Waisman, Thomas Blankenstein, Mark Allegretta, Amitabh Gaur, Nick Ling, Roland Martin, Christopher Piercy
Publikováno v:
Nature. 379(6563)
Following induction of experimental encephalomyelitis with a T-cell clone, L10C1, that is specific for the myelin basic protein epitope p87-99, the inflammatory infiltrate in the central nervous system contains a diverse collection of T cells with he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::573d37d80bb04b6c88179247543385dc
https://pubmed.ncbi.nlm.nih.gov/8552189
https://pubmed.ncbi.nlm.nih.gov/8552189
Publikováno v:
Immunoneurology ISBN: 9783642647413
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae1e992b39de8e912bdab1de4e57734e
https://doi.org/10.1007/978-3-642-61191-9_13
https://doi.org/10.1007/978-3-642-61191-9_13
Autor:
R. Mehta, R. C. Siegel, T. Tram, Lawrence Steinman, Leslie J. Dorfman, Suzanne Hodgkinson, Mae Lim, J. W. Lindsey, Christopher Piercy, Dennis J. Mitchell, Dieter R. Enzmann
Publikováno v:
Neurology. 44(3 Pt 1)
We conducted an open trial of cM-T412, a chimeric monoclonal anti-CD4 antibody, in 29 patients with MS. This antibody caused a prompt and long-lasting depletion of circulating CD4 (helper/inducer) lymphocytes. The mean (±SE) CD4 count for the group
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8abec35a8f8f2e1c56aff009207ec01e
https://pubmed.ncbi.nlm.nih.gov/8145907
https://pubmed.ncbi.nlm.nih.gov/8145907
Erratum: Treatment of experimental encephalomyelitis with a peptide analogue of myelin basic protein
Autor:
Stefan Brocke, Koenraad Gijbels, Mark Allegretta, Iris Ferber, Christopher Piercy, Thomas Blankenstein, Roland Martin, Ursula Utz, Nathan Karin, Dennis Mitchell, Timo Veromaa, Ari Waisman, Amitabh Gaur, Paul Conlon, Nicholas Ling, Paul J. Fairchild, David C. Wraith, Anne O'Garra, C. Garrison Fathman, Lawrence Steinman
Publikováno v:
Nature. 392:630-630
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92937069bf86881e03bb7b38b93371dc
https://doi.org/10.1038/33465
https://doi.org/10.1038/33465