Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Christopher Petucci"'
Autor:
Jae-Ho Lee, Younghoon Go, Do-Young Kim, Sun Hee Lee, Ok-Hee Kim, Yong Hyun Jeon, Taeg Kyu Kwon, Jae-Hoon Bae, Dae-Kyu Song, Im Joo Rhyu, In-Kyu Lee, Minho Shong, Byung-Chul Oh, Christopher Petucci, Jeen-Woo Park, Timothy F. Osborne, Seung-Soon Im
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 2, Pp 238-252 (2020)
Obesity: Possible protective enzyme identified An enzyme that limits the build-up of reactive oxygen species (ROS) in fat cells protects mice against metabolic stress during a high-fat diet. Calorie overload leads to high levels of damaging ROS in th
Externí odkaz:
https://doaj.org/article/106facf445dc4fc98d23964a4547c840
Autor:
Jae-Ho Lee, Younghoon Go, Do-Young Kim, Sun Hee Lee, Ok-Hee Kim, Yong Hyun Jeon, Taeg Kyu Kwon, Jae-Hoon Bae, Dae-Kyu Song, Im Joo Rhyu, In-Kyu Lee, Minho Shong, Byung-Chul Oh, Christopher Petucci, Jeen-Woo Park, Timothy F. Osborne, Seung-Soon Im
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 6, Pp 988-988 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/4e7ee20877a342bb9f13fecc98edcca4
Autor:
Virginia S. Hahn, Christopher Petucci, Min-Soo Kim, Kenneth C. Bedi, Hanghang Wang, Sumita Mishra, Navid Koleini, Edwin J. Yoo, Kenneth B. Margulies, Zoltan Arany, Daniel P. Kelly, David A. Kass, Kavita Sharma
Publikováno v:
Circulation. 147:1147-1161
Background: The human heart primarily metabolizes fatty acids, and this decreases as alternative fuel use rises in heart failure with reduced ejection fraction (HFrEF). Patients with severe obesity and diabetes are thought to have increased myocardia
Autor:
David C. Schultz, Robert M. Johnson, Kasirajan Ayyanathan, Jesse Miller, Kanupriya Whig, Brinda Kamalia, Mark Dittmar, Stuart Weston, Holly L. Hammond, Carly Dillen, Jeremy Ardanuy, Louis Taylor, Jae Seung Lee, Minghua Li, Emily Lee, Clarissa Shoffler, Christopher Petucci, Samuel Constant, Marc Ferrer, Christoph A. Thaiss, Matthew B. Frieman, Sara Cherry
Publikováno v:
Nature. 604:134-140
The SARS-CoV-2 virus has infected more than 261 million people and has led to more than 5 million deaths in the past year and a half
Autor:
Steven R. Smith, Christopher Bock, Alok Pachori, Joshua S Smith, Stephanie A. Parsons, Stephen J. Gardell, Fanchao Yi, Christopher Petucci, Karen P. Jones, Katie L Whytock, Hui Xie, Karen D. Corbin
Publikováno v:
The American Journal of Clinical Nutrition. 114:267-280
BACKGROUND Low-calorie diet (LCD)-induced weight loss demonstrates response heterogeneity. Physiologically, a decrease in energy expenditure lower than what is predicted based on body composition (metabolic adaptation) and/or an impaired capacity to
Autor:
Kunho Chung, Jie Xu, Yaroslav Kaminskiy, Hongxing Sun, Min-Soo Kim, Christopher Petucci, Tong Wang, Rahul M Kohli, J. Joseph Melenhorst
Publikováno v:
Blood. 140:628-629
Autor:
Michael J. Previs, Thomas S. O’Leary, Michael P. Morley, Bradley M. Palmer, Martin LeWinter, Jaime M. Yob, Francis D. Pagani, Christopher Petucci, Min-Soo Kim, Kenneth B. Margulies, Zoltan Arany, Daniel P. Kelly, Sharlene M. Day
Publikováno v:
Circ Heart Fail
Background: Defects in energetics are thought to be central to the pathophysiology of hypertrophic cardiomyopathy (HCM); yet, the determinants of ATP availability are not known. The purpose of this study is to ascertain the nature and extent of metab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8b1ef40680e48687276cd37d394a34e
https://europepmc.org/articles/PMC9708114/
https://europepmc.org/articles/PMC9708114/
Autor:
Timothy F. Osborne, Minho Shong, Inkyu Lee, Dae Kyu Song, Jae-Ho Lee, Younghoon Go, Do Young Kim, Ok Hee Kim, Yong Hyun Jeon, Jeen Woo Park, Byung-Chul Oh, Im Joo Rhyu, Taeg Kyu Kwon, Jae-Hoon Bae, Sun Hee Lee, Christopher Petucci, Seung Soon Im
Publikováno v:
Experimental & Molecular Medicine
Experimental and Molecular Medicine, Vol 52, Iss 2, Pp 238-252 (2020)
Experimental and Molecular Medicine, Vol 52, Iss 2, Pp 238-252 (2020)
Isocitrate dehydrogenase 2 (IDH2) is an NADP+-dependent enzyme that catalyzes the oxidative decarboxylation of isocitrate to α-ketoglutarate in the mitochondrial matrix, and is critical for the production of NADPH to limit the accumulation of mitoch
Autor:
Virginia S Hahn, Zoltan Arany, Min-Soo Kim, Christopher Petucci, Kenneth Bedi, Kenneth B Margulies, Daniel P Kelly, David A Kass, Kavita Sharma
Publikováno v:
Circulation. 144
Introduction: Myocardial fatty acid oxidation is impaired in heart failure with reduced ejection fraction (HFrEF) but increases with obesity with diabetes. HF with preserved EF (HFpEF) patients are often obese, but their myocardial metabolomic profil
Autor:
Daniel P. Kelly, Christopher Petucci, Neil B. Wood, Michael Morley, Brad Palmer, Jaime Yob, Martin M. LeWinter, Kenneth B. Margulies, Sharlene M. Day, Thomas S. O’Leary, Minsoo Kim, Zoltan Arany, Michael J. Previs, Francis D. Pagani
RationaleImpaired cardiac energetics in hypertrophic cardiomyopathy (HCM) is thought to result from increased ATP utilization at the sarcomere and is believed to be central to pathophysiology. However, the precise defects in cardiac metabolism and su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::226b3efc6e4e0baaa9d2523e11348a8a
https://doi.org/10.1101/2021.08.18.455967
https://doi.org/10.1101/2021.08.18.455967