Zobrazeno 1 - 10
of 163
pro vyhledávání: '"Christopher Parrish"'
Autor:
Thea Chandler, Christopher Parrish, Marina Karakantza, Jonathan Carmichael, David Pawson, Gordon Cook, Frances Seymour
Publikováno v:
eJHaem, Vol 4, Iss 3, Pp 625-630 (2023)
Abstract Collection of peripheral blood stem cells (PBSCs) for autologous stem cell transplant (ASCT) requires mobilization from the bone marrow. There is variation in mobilization choice; during the COVID‐19 pandemic BSBMT&CT guidelines recommende
Externí odkaz:
https://doaj.org/article/17ec11bee411472ab0b3f11ce50de116
Autor:
Matthew Holmes, Gina B. Scott, Samuel Heaton, Tyler Barr, Basem Askar, Louise M.E. Müller, Victoria A. Jennings, Christy Ralph, Cathy Burton, Alan Melcher, Peter Hillmen, Christopher Parrish, Fiona Errington-Mais
Publikováno v:
Molecular Therapy: Oncolytics, Vol 29, Iss , Pp 17-29 (2023)
Primary drug resistance and minimal residual disease are major challenges in the treatment of B cell neoplasms. Therefore, this study aimed to identify a novel treatment capable of eradicating malignant B cells and drug-resistant disease. Oncolytic v
Externí odkaz:
https://doaj.org/article/5203c050e9894f55a9405ad6fce9ab42
Autor:
Jonathan Carmichael, Frances Seymour, Graham McIlroy, Sarrah Tayabali, Rosie Amerikanou, Sylvia Feyler, Rakesh Popat, Guy Pratt, Christopher Parrish, A. John Ashcroft, Graham H. Jackson, Gordon Cook
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract The COVID-19 pandemic has had global healthcare impacts, including high mortality from SARS-CoV-2 infection in cancer patients; individuals with multiple myeloma (MM) are especially susceptible to poor outcomes. However, even for MM patients
Externí odkaz:
https://doaj.org/article/4261423c0dbc42d4ae909538097e3338
Autor:
Holger W. Auner, Sarah R. Brown, Katrina Walker, Jessica Kendall, Bryony Dawkins, David Meads, Gareth J. Morgan, Martin F. Kaiser, Mark Cook, Sadie Roberts, Christopher Parrish, Gordon Cook
Publikováno v:
Blood Cancer Journal, Vol 12, Iss 4, Pp 1-8 (2022)
Abstract The all-oral combination of ixazomib, cyclophosphamide, and dexamethasone (ICD) is well tolerated and effective in newly diagnosed and relapsed multiple myeloma (MM). We carried out MUKeight, a randomised, controlled, open, parallel group, m
Externí odkaz:
https://doaj.org/article/6f53ac33e4584ab790d1f18247c35ac3
Autor:
Roger Owen, Mark Cook, David Meads, David A Cairns, Christopher Parrish, Gordon Cook, Kwee Yong, Guy Pratt, Martin Kaiser, Karthik Ramasamy, Graham Jackson, Catherine Olivier, Amy Beth Coulson, Kara-Louise Royle, Anna Hockaday, Ruth de Tute, Bryony Dawkins, Mark Drayson, Jonathan Sive, Holger W Auner, Sergio Quezada, Lorna Barnard, Rhiannon Lambkin, Andrea Paterson, Mike Chapman, Rakesh Popat, Ceri Bygrave, Andrew Chantry, Samir Asher
Publikováno v:
BMJ Open, Vol 12, Iss 11 (2022)
Introduction Multiple myeloma is a plasma cell malignancy that accounts for 1%–2% of newly diagnosed cancers.At diagnosis, approximately 20% of patients can be identified, using cytogenetics, to have inferior survival (high-risk). Additionally, sta
Externí odkaz:
https://doaj.org/article/bf5f5424894a43a2927ade7759c778ff
Autor:
Roger Owen, John Jones, David Meads, David A Cairns, Christopher Parrish, Gordon Cook, Neil Rabin, Matthew Jenner, Martin Kaiser, Kevin Boyd, Graham Jackson, Catherine Olivier, Amy Beth Coulson, Kara-Louise Royle, Charlotte Pawlyn, Anna Hockaday, Jennifer Bird, Stella Bowcock, Ruth de Tute, Hayley Gardner, Bryony Dawkins, Rowena Henderson, Phillip Best, Bhuvan Kishore, Mark Drayson
Publikováno v:
BMJ Open, Vol 12, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/3d2818c0a21d4f5daf3843685e054b9c
Publikováno v:
Current Issues in Education, Vol 22, Iss 3 (2021)
The benefits of team learning include increased achievement, increased motivation, and greater retention of concepts learned. While team learning has been implemented since the early 20th century, instructors in higher education settings may still ex
Externí odkaz:
https://doaj.org/article/8ae612f388a443cf898953b00ded25f7
Autor:
Catherine S. Y. Lecat, Jessica B. Taube, William Wilson, Jonathan Carmichael, Christopher Parrish, Gabriel Wallis, Charalampia Kyriakou, Lydia Lee, Shameem Mahmood, Xenofon Papanikolaou, Neil K. Rabin, Jonathan Sive, Ashutosh D. Wechalekar, Kwee Yong, Gordon Cook, Rakesh Popat
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundThe treatment paradigm for multiple myeloma (MM) continues to evolve with the development of novel therapies and the earlier adoption of continuous treatments into the treatment pathway. Lenalidomide-refractory patients now represent a chal
Externí odkaz:
https://doaj.org/article/824d4c0c5b7c4fb48057514e0769e341
Autor:
Victoria Jennings, Christopher Parrish, Christy Ralph, Alan Melcher, Adel Samson, Gordon Cook, Fiona Errington-Mais, Matt Coffey, Munitta Muthana, Gemma Migneco, Louise M E Müller, Gina B Scott, Jenny Down, Sancha King, Basem Askar, Babatunde Oyajobi, Karen Scott, Emma West, Elizabeth J Ilett, Michelle Lawson
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
Background Multiple myeloma (MM) remains an incurable disease and oncolytic viruses offer a well-tolerated addition to the therapeutic arsenal. Oncolytic reovirus has progressed to phase I clinical trials and its direct lytic potential has been exten
Externí odkaz:
https://doaj.org/article/db50054d7a414d2980de99757b9e839e
Autor:
Louise M. E. Müller, Matthew Holmes, Joanne L. Michael, Gina B. Scott, Emma J. West, Karen J. Scott, Christopher Parrish, Kathryn Hall, Sina Stäble, Victoria A. Jennings, Matthew Cullen, Stewart McConnell, Catherine Langton, Emma L. Tidswell, Darren Shafren, Adel Samson, Kevin J. Harrington, Hardev Pandha, Christy Ralph, Richard J. Kelly, Gordon Cook, Alan A. Melcher, Fiona Errington-Mais
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-16 (2019)
Abstract Background The oncolytic virus, coxsackievirus A21 (CVA21), has shown promise as a single agent in several clinical trials and is now being tested in combination with immune checkpoint blockade. Combination therapies offer the best chance of
Externí odkaz:
https://doaj.org/article/45333d28906e4c79a697ecb02c401857